H. Llewelyn (Llew) Roderick B.Sc., Ph.D.

MR5 Room 3005

Targeting the epigenome to increase cardiomyocyte proliferation and cardiac regeneration Epigenomic remodelling during cardiomyocyte maturation serves to suppress fetally expressed genes and promote the expression of genes necessary for adult function. Genes involved in cell cycle activity that are expressed … Read More

Muge Kuyumcu-Martinez, PhD

MR5 Room 3005

RNA binding proteins: Wizards of gene regulation in the heart Mutations in RNA binding proteins are associated with adult and congenital heart diseases. It is unclear how these RNA binding proteins alter gene expression in the heart and cause heart … Read More

Nick Chavkin, PhD

Location - Room 3005 MR5

Mechanisms of Endothelial Cell Fate Determination – Applications to Cardiac Tissue Regeneration Endothelial cell specification into arterial and venous phenotypes is critical for the development of a circulatory network, and requires coordination between extrinsic and intrinsic signaling. These maturation events … Read More

Jiliang Zhou, M.D., PhD

MR5 Room 3005

The Dark That Matters: Essential Role of the Long Non-coding RNA CARMN in Regulating Smooth Muscle Phenotype Professor, Department of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, GA

Edward Moreira Bahnson, PhD

MR5 Room 3005

Redox Modulation and Targeted Drug Delivery for Cardiovascular Disease and Beyond Redox dysfunction is causally associated with a wide array of human pathologies. Particularly, redox dysfunction promotes the development of cardiovascular disease. However, clinical translation of antioxidant-therapy has yielded underwhelming … Read More

Jose Lopez, MD

MR5 Room 3005

Functional interactions between von Willebrand factor and lipoproteins: Implications for microvascular function and atherosclerosis In this lecture, I will describe the biochemistry and physics of VWF self-association, a process that produces strands and fibers with high adhesive capacity for platelets. … Read More

Zhiyu Dai, PhD, FAHA

MR5 Room 3005

Role of Endothelial Dysfunction in the Pathogenesis of Pulmonary Arterial Hypertension. The endothelial cell-specific role in PAH is multi-faceted and impacts upon numerous pathophysiological processes including vasoconstriction, inflammation, metabolism, and oxidative/nitrative stress, as well as cell viability, growth.I will describe … Read More

Amreen Mughal, PhD

MR5 Room 3005

ElectroCalcium Coupling and Alzheimer’s Disease This talk will focus on the neurovascular coupling mechanisms involved in the control of blood flow in the brain. The talk will also describe how neurovascular coupling mechanisms get altered in a mouse model of … Read More

Valentina Lo Sardo, PhD

MR5 Room 3005

TAKING THE RISK: Stem cell-based functional genomics to uncover cardiovascular risk The Lo Sardo laboratory combines pluripotent stem cell potential and functional genomics to understand how common genetic variants among individuals, including those in non-coding portions of the genome, contribute … Read More

Natasha Sheybani, Phd

MR5 Room 3005

Immunoengineering Next-Generation Cancer Therapies with Focused Ultrasound Despite the remarkable promise of cancer immunotherapy, a significant fraction of patients with solid tumors are yet unable to realize its unparalleled benefits. In this talk, I will introduce focused ultrasound (FUS) - … Read More

Vlad Serbulea, PhD

MR5 Room 3005

Rerouting Smooth Muscle Glycolysis Rescues Atherosclerosis-associated Mortality in Mice Heart attacks or strokes stemming from rupture or erosion of unstable atherosclerotic plaques lead to over half a million deaths annually. Postmortem studies of human coronary arteries correlated stable atherosclerotic lesions … Read More

Javid Moslehi, M.D.

MR5 Room 3005

Immune checkpoint inhibitor (ICI)-Myocarditis: Insights into cardiac-immune regulation Cardio-oncology (the cardiovascular care of cancer patients) has developed as a new translational and clinical field based on the expanding repertoire of mechanism-based cancer therapies. Cardio-oncology can also serve as a novel … Read More