Our Mission

The Robert M. Berne Cardiovascular Research Center was established to expand basic, translational, and clinical research of cardiovascular diseases. Cardiovascular diseases, including congestive heart failure, hypertension, atherosclerosis, stroke, aneurysms, and vascular auto-immune diseases are the most common cause of death and disability in the United States, and account for approximately 30% of deaths and health care costs annually in this country and developed societies.

The mission of the Robert M. Berne Cardiovascular Research Center is to support interdisciplinary research in basic, translational and clinical cardiovascular sciences, including cardiovascular development, function, pathophysiology, pharmacology, genetics, genomics, and proteomics, and to apply this knowledge to better understand the causes of cardiovascular diseases and to pioneer development of new innovative therapies and approaches to prevent or treat them.

Goals and Objectives

  • To support basic, translational, and clinical research that can be translated into therapies and improve patient care
  • To provide resources that enhance research in cardiovascular related diseases
  • To disseminate knowledge by lectures, seminars and other educational opportunities
  • To support training of pre- and postgraduate students, residents and fellows in the cardiovascular sciences and cardiovascular medicine
  • To help integrate cardiovascular research across labs, departments, and schools at UVA as well as with outside institutions including facilitating collaborative studies
  • To assist CVRC investigators in developing a plan for translating research findings into products or procedures that benefit patients including providing advice on protecting intellectual property, establishing biotech startup companies, and licensing technology to companies


Career Development-The Editorial Perspective

Dr. Andrew Dudley, PhDHarrison Distinguished Professor of Microbiology, Immunology, & Cancer BiologyUniversity of Virginia

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MR5 Room 1005,

Iris Jaffe, M.D., PhD

Endothelial Inflammation as a Mechanism of Plaque Rupture and Cardiovascular Ischemic Events: Explaining Clinical Observations The Jaffe lab brings clinical observations to the bench to explore mechanisms with the goal of enhancing understanding and ultimately improving treatment of human vascular … Read More

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MR5 Room 3005,

Career Development-Resilience and Difficult Conversations

Rachel Letteri, PhD; Associate Professor Chemical Engineering Lorelei Stoica, PhD; Executive Director, Nonclinical research at Ultragenyx Pharmaceuticals

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MR5 Room 1005,

Monica Lee, PhD

Deciphering the role of nucleoporin93 (Nup93) in endothelial and vascular function The vascular network is uniquely subject to mechanical changes and hence capable of perceiving various biophysical forces. While emerging studies identify nucleoskeletal elements (i.e. nuclear lamina) and linker of … Read More

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MR5 Room 3005,
MR6 Room 2502,