ElectroCalcium Coupling and Alzheimer’s Disease This talk will focus on the neurovascular coupling mechanisms involved in the control of blood flow in the brain. The talk will also describe how neurovascular coupling mechanisms get altered in a mouse model of … Read More
TAKING THE RISK: Stem cell-based functional genomics to uncover cardiovascular risk The Lo Sardo laboratory combines pluripotent stem cell potential and functional genomics to understand how common genetic variants among individuals, including those in non-coding portions of the genome, contribute … Read More
Victoria Milosek, Nareen Anwar, & Kelsey Watts Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease https://www.nature.com/articles/s44161-021-00002-8
Immunoengineering Next-Generation Cancer Therapies with Focused Ultrasound Despite the remarkable promise of cancer immunotherapy, a significant fraction of patients with solid tumors are yet unable to realize its unparalleled benefits. In this talk, I will introduce focused ultrasound (FUS) - … Read More
Luke - Endothelial Hemoglobin Alpha Mediates Iron Regulation of Endothelial Nitric Oxide Alex - Network analysis of the healthy mouse transcriptome identifies genes modulating cardiac development
Maddie Jackson - The role of Cx37 in lymphatic valve formation Jennifer Korchak - Mass spectrometry-based proteogenomics approach for detection of protein isoforms colocalized with coronary artery disease Kelsey Watts - Impact of sodium-glucose cotransporter 2 inhibitors on macrophage polarization … Read More
Rerouting Smooth Muscle Glycolysis Rescues Atherosclerosis-associated Mortality in Mice Heart attacks or strokes stemming from rupture or erosion of unstable atherosclerotic plaques lead to over half a million deaths annually. Postmortem studies of human coronary arteries correlated stable atherosclerotic lesions … Read More
Immune checkpoint inhibitor (ICI)-Myocarditis: Insights into cardiac-immune regulation Cardio-oncology (the cardiovascular care of cancer patients) has developed as a new translational and clinical field based on the expanding repertoire of mechanism-based cancer therapies. Cardio-oncology can also serve as a novel … Read More
Noah Perry - 5th Year PhD Candidate Biomedical Engineering, Civelek Lab Ian Liyayi - 5th Year PhD Candidate MIC, Criss Lab Deborah Powers - 5th Year PhD Candidate Biochemistry and Molecular Genetics, Papin Lab Mike Lemke - 4th Year PhD … Read More
Kaitlyn - Systems-enabled drug repurposing for cardiomyocyte proliferation Wyatt - Novel roles for hydrogen peroxide in vascular function and immunology Skylar - Anti-Inflammatory Therapeutic Loading of Atherosclerotic Plaque-Targeted Nanofibers
Endothelium at the Interface of Lipid Metabolism, Vascular Function and Disease The endothelium is the key cell type at the interface of circulating lipids and the vessels wall. New insights into how lipids and inflammatory signaling impacts endothelial cell functions … Read More
Nicholas Chavkin, PhD - Postdoctoral Researcher University of Virginia Matthew DeWitt, PhD - Senior Scientist University of Virginia
