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Valentina Lo Sardo, PhD
November 16, 2023 @ 11:00 am – 12:00 pm
TAKING THE RISK: Stem cell-based functional genomics to uncover cardiovascular risk
The Lo Sardo laboratory combines pluripotent stem cell potential and functional genomics to understand how common genetic variants among individuals, including those in non-coding portions of the genome, contribute to altering cell physiology, cell state, and fate commitment.
Emphasis is posed on understanding non-coding risk factors, cell-type vulnerability, as well as ethnicity-based vulnerability to complex human diseases. Using multidisciplinary approaches, including pluripotent stem cell differentiation, genome editing, transcriptomics, imaging, and proteomics, my lab aims to identify new molecular mechanisms triggering cardiovascular disease and cancer.
Assistant Professor, Department of Cell and Regenerative Biology, University of Wisconsin-Madison, School of Medicine and Public Health, WI