GPR126 is a mechanoreceptor by which the endocardium senses cardiac load We have combined the use of genetic and physiologic approaches in mice to define how the adhesion GPCR GPR126 functions in vivo. Our findings reveal that GPR126 is activated by … Read More

Epigenetic Control of Smooth Muscle Differentiation: Insights from Smooth Muscle Dysfunction Syndrome Heterozygous ACTA2 p.R179 pathogenic variants cause Smooth Muscle Dysfunction Syndrome. ACTA2 encodes smooth muscle α-actin (SMA), and the p.R179 variant disrupts nuclear localization of SMA, leading to incomplete differentiation of smooth muscle … Read More

TBD Associate Professor of Medicine, University of Texas at Houston, McGovern Medical School Houston, Texas

Nutrition, Obesity, and Metabolism in Heart Failure: Mechanistic Insights and Translational Opportunities The presentation will discuss the metabolic and physiological effects of diet and obesity on cardiometabolic health, with a focus on heart failure. The talk will bridge basic and … Read More

TBD Assistant Professor of Physiology, Medical College of Wisconsin, Milwaukee, WI