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X-WR-CALNAME:Robert M. Berne Cardiovascular Research Center
X-ORIGINAL-URL:https://www.cvrc.virginia.edu
X-WR-CALDESC:Events for Robert M. Berne Cardiovascular Research Center
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20260924T110000
DTEND;TZID=America/New_York:20260924T120000
DTSTAMP:20260721T193947Z
CREATED:20260630T180111Z
LAST-MODIFIED:20260721T193947Z
UID:6393-1790247600-1790251200@www.cvrc.virginia.edu
SUMMARY:Elisa Boscolo\, PhD
DESCRIPTION:Cellular and molecular mechanisms driving aberrant development in a novel model of Venous Malformation \n\n\n\n Patients with venous malformation (VM) develop vascular lesions consisting of massively enlarged and dysmorphic veins. These lesions cause significant disfigurement\, chronic pain\, and complications such as bleeding and coagulopathy. VMs are associated with somatic\, gain-of-function mutations in the endothelial cell receptor kinase TIE2. The cellular and molecular mechanisms by which TIE2 mutations drives formation of VM are still not fully understood. To unravel these mechanisms\, we have developed the first-to-date murine model of TIE2 p.L914F-driven VM. \n\n\n\n\n\n\n\nAssociate Professor of Pediatrics\, University of Cincinnati College of Medicine\, Division of Experimental Hematology and Cancer Biology\, Cancer and Blood Diseases Institute\, Cincinnati Children’s Hospital Medical Center\, Cincinnati\, OH \n\n\n\n\n\n\n\nBoscolo CV July 2026Download\n\n\n\nBoscolo FlyerDownload
URL:https://www.cvrc.virginia.edu/event/elisa-boscolo-phd/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
ATTACH;FMTTYPE=image/jpeg:https://www.cvrc.virginia.edu/wp-content/uploads/2026/06/Elisa_Boscolo-photo.jpeg
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261001T110000
DTEND;TZID=America/New_York:20261001T120000
DTSTAMP:20260917T192823Z
CREATED:20260630T180439Z
LAST-MODIFIED:20260917T192823Z
UID:6395-1790852400-1790856000@www.cvrc.virginia.edu
SUMMARY:Maddie Jackson\, PhD Candidate
DESCRIPTION:Lymphatic endothelial cell cycle control enables lymphatic valve formation \n\n\n\nThe lymphatic vasculature relies on intraluminal valves to maintain unidirectional lymph flow and tissue fluid homeostasis. Disruption to their formation during embryonic development leads to congenital lymphedema\, or aberrant pooling of lymph in the tissues leading to tissue swelling\, fibrosis\, and localized immune dysfunction. Despite this\, our understanding of the mechanisms that regulate lymphatic valve formation is not complete. In my talk I will discuss how a Cx37-p27 signaling axis enables lymphatic valve formation through promoting a late G1 state in valve-forming lymphatic endothelial cells\, and how that late G1 state enables valve cell migration and valve leaflet formation. \n\n\n\n\n\n\n\nPhD Candidate\, Hirschi Lab\, University of Virginia\, Charlottesville VA \n\n\n\n\n\n\n\nMadeline Jackson_CV2026Download\n\n\n\nJackson Flyer
URL:https://www.cvrc.virginia.edu/event/maddie-jackson-phd-candidate/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
ATTACH;FMTTYPE=image/jpeg:https://www.cvrc.virginia.edu/wp-content/uploads/2026/06/Madeline-Jackson-Headshot3.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261008T110000
DTEND;TZID=America/New_York:20261008T120000
DTSTAMP:20260917T193348Z
CREATED:20260917T191029Z
LAST-MODIFIED:20260917T193348Z
UID:6534-1791457200-1791460800@www.cvrc.virginia.edu
SUMMARY:Nick Tsihlis\, PhD
DESCRIPTION:Nanoscale Materials to Target Diseases in the Vasculature \n\n\n\nCardiovascular disease is the leading cause of mortality globally\, with inflammation-inducing atherosclerotic plaque being the main contributing factor. The CANTOS trial showed that decreasing inflammation reduced cardiovascular events without lowering lipids\, but systemic anti-inflammatory administration was limited by off-target effects. Thus\, there is a great need for a new therapeutic that actively prevents progression of atherosclerotic plaques by modulating inflammatory pathways. Nanotechnology offers a noninvasive approach for the management of cardiovascular disease via targeted delivery of therapeutic agents that are otherwise limited by pharmacokinetics or toxicity from systemic administration. We have engineered a peptide amphiphile (PA) specifically targeted to sites of atherosclerosis by covalently incorporating an apolipoprotein A1 (ApoA1)-mimetic peptide. We showed that these PAs self-assemble into supramolecular nanofibers that localize to sites of atherosclerosis when intravenously administered to low-density lipoprotein receptor knock out (LDLR-/-) mice. Thus\, we seek to develop a multimodal\, targeted anti-inflammatory nanotherapeutic to prevent plaque progression. \n\n\n\n\n\n\n\nProfessor Department of Surgery and Biomedical Engineering\, University of Virginia\, Charlottesville VA. \n\n\n\n\n\n\n\nTsihlis CV 2026-09-11\n\n\n\nTsihlis Flyer
URL:https://www.cvrc.virginia.edu/event/nick-tsihlis-phd/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
ATTACH;FMTTYPE=image/jpeg:https://www.cvrc.virginia.edu/wp-content/uploads/2026/09/TsihlisNick-headshot-Aug2022.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261015T110000
DTEND;TZID=America/New_York:20261015T120000
DTSTAMP:20260630T185936Z
CREATED:20260630T185935Z
LAST-MODIFIED:20260630T185936Z
UID:6405-1792062000-1792065600@www.cvrc.virginia.edu
SUMMARY:Nick Leeper\, M.D.
DESCRIPTION:TBD \n\n\n\n\n\n\n\nProfessor of Medicine & Surgery\, Director of Vascular Research\, and Chief of Vascular Medicine\, Stanford University Medical Center\, CA
URL:https://www.cvrc.virginia.edu/event/nick-leeper-m-d/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261015T163000
DTEND;TZID=America/New_York:20261015T170000
DTSTAMP:20260709T123226Z
CREATED:20260630T190228Z
LAST-MODIFIED:20260709T123226Z
UID:6407-1792081800-1792083600@www.cvrc.virginia.edu
SUMMARY:CVTG RIP - Katie Pavelec\, AJ McKamy\, & Madison Doceti
DESCRIPTION:
URL:https://www.cvrc.virginia.edu/event/cvtg-rip-katie-pavelec-aj-mckamy-leigh-fremuth/
LOCATION:MR6 Room 2502
CATEGORIES:Research in Progress
ATTACH;FMTTYPE=image/jpeg:https://www.cvrc.virginia.edu/wp-content/uploads/2021/02/10R-lacZ20-web.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261022T110000
DTEND;TZID=America/New_York:20261022T120000
DTSTAMP:20260914T145715Z
CREATED:20260630T190534Z
LAST-MODIFIED:20260914T145715Z
UID:6409-1792666800-1792670400@www.cvrc.virginia.edu
SUMMARY:Esther Lutgens\, M.D.\, PhD
DESCRIPTION:Immune checkpoints in atherosclerosis: a new VISTA \n\n\n\nI will talk about the role of co-stimulatory and coinhibitory immune checkpoints in atherosclerosis. Not only will I highlight the dangers of immune checkpoint inhibition in cancer treatment on the vasculature\, I will also address the potential of targeting co-stimulatory and co-inhibitory immune checkpoints as therapy for atherosclerosis. \n\n\n\n\n\n\n\nProf. of Medicine\, Mayo Clinic\, Dept of Cardiovascular Medicine & Immunology\, Rochester\, MN \n\n\n\n\n\n\n\n120225Lutgens_Biosketch
URL:https://www.cvrc.virginia.edu/event/esther-lutgens-m-d-phd/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
ATTACH;FMTTYPE=image/png:https://www.cvrc.virginia.edu/wp-content/uploads/2026/06/headshot-Lutgens.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261029T110000
DTEND;TZID=America/New_York:20261029T120000
DTSTAMP:20260630T190739Z
CREATED:20260630T190706Z
LAST-MODIFIED:20260630T190739Z
UID:6411-1793271600-1793275200@www.cvrc.virginia.edu
SUMMARY:Pearl Quijada\, PhD
DESCRIPTION:TBD \n\n\n\n\n\n\n\n Assistant Professor\, Department of Integrative Biology and Physiology\, University of California\, Los Angeles
URL:https://www.cvrc.virginia.edu/event/pearl-quijada-phd/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261112T110000
DTEND;TZID=America/New_York:20261112T120000
DTSTAMP:20260630T191129Z
CREATED:20260630T191127Z
LAST-MODIFIED:20260630T191129Z
UID:6413-1794481200-1794484800@www.cvrc.virginia.edu
SUMMARY:Robert Baur\, PhD
DESCRIPTION:TBD \n\n\n\n\n\n\n\nFlorence Irving Assistant Professor of Medical Sciences\, Cardiometabolic Genomics Program\, Div. of Cardiology\, Dept. of Medicine\, Columbia University Irving Medical Center\, New York\, NY
URL:https://www.cvrc.virginia.edu/event/robert-baur-phd/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261119T110000
DTEND;TZID=America/New_York:20261119T120000
DTSTAMP:20260630T191454Z
CREATED:20260630T191453Z
LAST-MODIFIED:20260630T191454Z
UID:6415-1795086000-1795089600@www.cvrc.virginia.edu
SUMMARY:Katie Pavelec\, PhD
DESCRIPTION:TBD \n\n\n\n\n\n\n\nPostdoctoral Research Fellow\, Wolf Lab\, University of Virginia\, Charlottesville\, VA
URL:https://www.cvrc.virginia.edu/event/katie-pavelec-phd/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261119T160000
DTEND;TZID=America/New_York:20261119T173000
DTSTAMP:20260630T192145Z
CREATED:20260630T191632Z
LAST-MODIFIED:20260630T192145Z
UID:6417-1795104000-1795109400@www.cvrc.virginia.edu
SUMMARY:CVTG RIP - Journal Club
DESCRIPTION:
URL:https://www.cvrc.virginia.edu/event/cvtg-rip-journal-club-4/
LOCATION:MR6 Room 2502
CATEGORIES:Research in Progress
ATTACH;FMTTYPE=image/jpeg:https://www.cvrc.virginia.edu/wp-content/uploads/2021/03/In-vivo-cell-cycling-cardiomyocytes-in-the-post-natal-mouse-heart-rotate-2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261203T110000
DTEND;TZID=America/New_York:20261203T120000
DTSTAMP:20260630T191919Z
CREATED:20260630T191917Z
LAST-MODIFIED:20260630T191919Z
UID:6419-1796295600-1796299200@www.cvrc.virginia.edu
SUMMARY:Sarah Sheppard\, M.D.\,M.S.\,PhD
DESCRIPTION:TBD
URL:https://www.cvrc.virginia.edu/event/sarah-sheppard-m-d-m-s-phd/
LOCATION:MR5 Room 3005
CATEGORIES:CVRC Seminar Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20261217T160000
DTEND;TZID=America/New_York:20261217T173000
DTSTAMP:20260709T123153Z
CREATED:20260630T192104Z
LAST-MODIFIED:20260709T123153Z
UID:6421-1797523200-1797528600@www.cvrc.virginia.edu
SUMMARY:CVTG RIP - Sarah Duclos\, Jeevan Tewari\, & Leigh Fremuth
DESCRIPTION:
URL:https://www.cvrc.virginia.edu/event/cvtg-rip-sarah-duclos-jeevan-tewari-madison-doceti/
LOCATION:MR6 Room 2502
CATEGORIES:Research in Progress
ATTACH;FMTTYPE=image/jpeg:https://www.cvrc.virginia.edu/wp-content/uploads/2021/03/Glass_slide_dual_image_1_merge-web.jpg
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