Events

Microglial cyclooxygenase-1 modulates cerebral basal capillary tone in vivo Microglia and border associated macrophages have been implicated in hypercapnia, but it is unknown which myeloid cell modulates which vessel type. Previously, we documented in mice myeloid cell association with the brain … Read More

The New Modern Medicine In this talk, Jonathan Fuller will share research from his book The New Modern Medicine about how epidemiology transformed scientific medicine during the previous century, including in areas such as cardiovascular and cancer care, right down to its … Read More

Vascular inflammation in obesity and lung injury Endothelial signaling microdomains precisely regulate vascular homeostasis. However, the mechanism by which the abnormalities at these microdomains increase vascular tone and permeability is poorly understood. My work has defined a novel paracrine signaling … Read More

Intersecting pathways: Immune mechanisms linking cardiovascular disease and cancer Cardiovascular disease and cancer, while distinct, exhibit cross-disease communication that exacerbates morbidity. Cancer patients are at significantly increased risk for CVD and ischemic cardiovascular events can in turn accelerate tumor growth. Immune … Read More

Beyond Neurons: Vascular Pathways in Autism Dr. Lacoste and his team have established a unique research niche bridging basic and translational neurovascular biology. The Lacoste Lab, established in 2016, has discovered novel mechanisms regulating cerebrovascular maturation1, and the vascular contributions … Read More

Mechanisms of Reduced Exercise Capacity: Insights from Novel MRI Methods Reduced exercise capacity (reduced VO2max, oxygen consumption) is a hallmark feature of heart failure, affecting quality of life and reflecting disease severity and outcomes.  Survivors of breast cancer therapy are at increased … Read More