Pulmonary vascular dynamics: rise and fall of SMC clones The presentation will discuss vascular remodeling in the context of pulmonary hypertension. It will focus on cellular and molecular mechanisms that regulate expansion of smooth muscle cells down the pulmonary arteriole … Read More
Tammi Pavelec, PhD – Professor of Math and Physical Sciences, University of St. Francis Maurits Jansen, PhD – Director Molecular Imaging Core and Professor in Department of Radiology and Molecular Imaging, UVa Jeff Smith, PhD – Professor Biochemistry and Molecular … Read More
Dr. Kimberly Kelly Professor of Biomedical Engineering, University of Virginia, Founder of ZielBio, Editor in Chief of Molecular Imaging and Biology
Translational Tales of the Human Microvasculature This presentation will provide an overview of the translational projects beingconducted in the Freed laboratory with particular focus on the importance of studyingthe microvasculature, mechanisms of human microvascular dysfunction, andstrategies in which to increase … Read More
Joelle Martin, PhD Director, Medical Information and Scientific Communication 4D Molecular Therapeutics
TGF-beta signaling cascades in cardiac repair and fibrosis Myocardial fibrosis is a common pathophysiological feature of most cardiac diseases and may be either reparative or maladaptive. This presentation will address: (a) the cellular mediators of cardiac fibrosis; (b) the molecular … Read More
Impaired Clearance of Amyloid Fibrils in Men With Loss of the Y Chromosome Condition.
Hypertension Compromises Tissue-Resident Endothelial Progenitor Cells, Driving Impaired Vascular Regeneration and Highlighting Partial Reprogramming as a Therapeutic Strategy I will present some preliminary data demonstrating a reduction in tissue-resident endothelial progenitor cells (EPCs) in hypertensive animals. I will show that … Read More
Dichotomous Roles of Inflammation in Atherosclerosis Thromboembolic events secondary to rupture or erosion of advanced atherosclerotic lesions are the underlying cause of heart attacks and stroke which are the leading cause of death in the United States and worldwide. Whereas … Read More
