Jiliang Zhou, M.D., PhD

The Dark That Matters: Essential Role of the Long Non-coding RNA CARMN in Regulating Smooth Muscle Phenotype

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1. Gain information about the underappreciated role of non-coding RNAs in smooth muscle biology and the discovery of long non-coding RNA CARMN.
2. The long non-coding RNA CARMN is specifically expressed in smooth muscle cells and is the first lncRNA identified indispensable for smooth muscle contractility.
3. Loss-of-function mutation of CARMN in humans may cause visceral myopathy and aortic aneurysm.

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Professor, Department of Pharmacology & Toxicology, Medical College of Georgia, Augusta University, Augusta, GA