Robert M. Carey


Primary Appointment

Dean Emeritus and Professor, Medicine- Endocrinology and Metabolism


  • Clinical Fellowship, Endocrinology, Vanderbilt Medical Center
  • Clinical Fellowship, Hypertension, St. Mary's Hospital Medical School
  • MD, Vanderbilt University
  • Residency, Internal Medicine, New York Hospital-Cornell Medical Center

Research Interests

Hormonal control of blood pressure and kidney function; renin-angiotensin-aldosterone system; dopominergic system; renal and vascular paracrine systems; cell and molecular biology of vascular hormones.

Research Description

Dr. Carey's research is focused on understanding the pathophysiologic mechanisms of hypertension. He is studying the function of dopamine and angiotensin receptors in the kidney , heart and peripheral blood vessels. His laboratory has pioneered the discovery of the function of renal D1-like receptors and angiotensin AT-2 receptors. Current projects involve the role of AT-2 receptors in sodium excretion and hypertension; the interaction of dopamine receptors with angiotensin receptors within the kidney, the role of extracellular renal cyclic GMP in pressure-natriuresis and the role of urinary angiotensinogen as a marker for activation of the intrarenal renin-angiotensin system.

Personal Statement

Dr. Carey is a world renowned cardiovascular endocrinologist and a past president of The Endocrine Society.


  • Basic Cardiovascular Research Training Grant

Selected Publications

Kemp BA, Howell NL, Keller SR, Gildea JJ, Padia SH, Carey RM, AT2 Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II-Dependent Hypertension., 2016; Circulation research. () . PMID: 27323774 | PMCID: PMC4975636

Manichaikul A, Rich SS, Allison MA, Guagliardo NA, Bayliss DA, Carey RM, Barrett PQ, KCNK3 Variants Are Associated With Hyperaldosteronism and Hypertension., 2016; Hypertension (Dallas, Tex. : 1979). 68(2) 356-64. PMID: 27296998 | PMCID: PMC4945430

Funder JW, Carey RM, Mantero F, Murad MH, Reincke M, Shibata H, Stowasser M, Young WF, The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline., 2016; The Journal of clinical endocrinology and metabolism. 101(5) 1889-916. PMID: 26934393

Gasparetto A, Angle JF, Darvishi P, Freeman CW, Norby RG, Carey RM, Clinical impact of strict criteria for selectivity and lateralization in adrenal vein sampling., 2016; Hormones (Athens, Greece). 15(2) 264-70. PMID: 27376419

Carey RM, Resistant Hypertension: Mineralocorticoid Receptor Antagonist or Renal Denervation?, 2015; Hypertension (Dallas, Tex. : 1979). 67(2) 278-80. PMID: 26693820 | PMCID: PMC4713293

Gildea JJ, Xu P, Carlson JM, Gaglione RT, Bigler Wang D, Kemp BA, Reyes CM, McGrath HE, Carey RM, Jose PA, Felder RA, The sodium-bicarbonate cotransporter NBCe2 (slc4a5) expressed in human renal proximal tubules shows increased apical expression under high-salt conditions., 2015; American journal of physiology. Regulatory, integrative and comparative physiology. 309(11) R1447-59. PMID: 26447209 | PMCID: PMC4698408

Natarajan AR, Eisner GM, Armando I, Browning S, Pezzullo JC, Rhee L, Dajani M, Carey RM, Jose PA, The Renin-Angiotensin and Renal Dopaminergic Systems Interact in Normotensive Humans., 2015; Journal of the American Society of Nephrology : JASN. 27(1) 265-79. PMID: 25977313 | PMCID: PMC4696568

Carey RM, The intrarenal renin-angiotensin system in hypertension., 2015; Advances in chronic kidney disease. 22(3) 204-10. PMID: 25908469

Kemp BA, Howell NL, Gildea JJ, Keller SR, Padia SH, Carey RM, Response to letter regarding article, "AT2 receptor activation induces natriuresis and lowers blood pressure"., 2014; Circulation research. 115(9) e26-7. PMID: 25301825 | PMCID: PMC4296969

Shada AL, Stokes JB, Turrentine FE, Simpson VB, Padia SH, Carey RM, Hanks JB, Smith PW, Adrenalectomy for adrenal-mediated hypertension: National Surgical Quality Improvement Program analysis of an institutional experience., 2014; The American surgeon. 80(11) 1152-8. PMID: 25347508