Cavitation Facilitated AAV Transduction This presentation will focus on multidisciplinary collaborative studies between CVRC and BME that investigating how ultrasound cavitation of microbubble contrast agents can produce site-targeted augmentation of AAV to the heart. These studies are intended to optimize … Read More
Follistatin mediates MASLD and MASH during hepatic insulin resistance on a high fructose diet MASLD (metabolic dysfunction-associated steatotic liver disease) and its progression to steatohepatitis (MASH) correlates with IR (insulin resistance). However, mice with complete hepatic IR owing to hepatic … Read More
Kelsey - Identification of sex dimorphisms in Endothelial-to-Mesenchymal Transition (endoMT) regulation in atherosclerotic disease Randall - Caveolin nanodiscs to investigate Cav-1 scaffolding Kaitlyn - Systems approaches identify drugs and genes regulating cardiomyocyte proliferation
From Data to Discovery: The Role of AI in Transforming Healthcare Research This talk will focus on the current and future role of AI tools in medical research, highlighting the subtleties of leveraging this powerful tool to increase efficiency and … Read More
Understanding Vascular Growth Kinetics At the structural level, the vascular system is a network of interconnected tubes responsible for delivering oxygen and nutrients throughout the body. While accurate, this portrayal understates the complexities inherent to its functionality. Beyond mere transportation, … Read More
Cell-specific LRP1 signaling in acute myocardial infarction Improving the treatment of acute myocardial infarction (AMI) to prevent heart failure (HF) and death remains an urgent unmet medical need. The AHA estimates that every 42 seconds an American will have an … Read More
Presenters - Katie Pavelec, Wyatt Schug, Maddie Jackson, and Skylar Loeb The paper is entitled: Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target https://www.sciencedirect.com/science/article/abs/pii/S0092867424010924?fr=RR-2&ref=pdf_download&rr=8d7d9c9dfbfbc97d
RMB CVRC & School of Medicine MPBP Seminar Role of extracellular myeloperoxidase in atherosclerosis development and late-stage pathogenesis Atherosclerosis is a chronic inflammatory disease whose clinical complications, including major adverse cardiovascular events (MACE) such as myocardial infarction (MI) and stroke, … Read More
Immune Metabolism of Human Salt Sensitive Hypertension Salt sensitive hypertension is an independent risk factor for cardiovascular disease. This talk will highlight novel mechanisms in immune metabolism contributing to salt-sensitivity of blood pressure. Associate Professor of Medicine, Clinical Pharmacology; Associate … Read More
Gabrielle Largoza - Identifying Cellular Mechanisms of KRAS-driven bAVM Caitlin Pavelec - MYBPC3 W1082* Trucation Mutation Drives Hypertrophic Cardiomyopathy in a Murine Model Chase Binion - Characterization of Plaque-Targeted Peptide Amphiphile Nanoparticles in a Rodent Model of Atherosclerosis
The Nitrate-Nitrite-Nitric Oxide Pathway: Ergogenic or Therapeutic - Who is it Good For Oral consumption of inorganic nitrate, which is abundant in green leafy vegetables and roots, has been shown to increase circulating plasma nitrite concentration, which in relatively low … Read More
