Dynamic nitrosation - palmitoylation of endothelial CD36 regulates serum lipids My talk will focus specifically on a new post-translational modification of a fatty acid translocase CD36 and how this regulates lipid uptake into endothelium. PhD Candidate Physiology, Isakson Lab, University of … Read More
Sujith Vijayan, M.A., Ph.D Associate Professor, Virginia Tech School of Neuroscience
Cell Signaling And Immune Cell Involvement In Neointima Formation Connexin (Cx) proteins form gap junctions, allowing for communication between cells. Alterations in gap junctions have been associated with pathological proliferation in disease since their discovery in the 1950s. Our studies … Read More
Toward a Therapy for Atherosclerosis - Discuss growth and composition of the arterial plaque, with possible targets of therapy - Discuss feasibility and drivers of atherosclerosis regression VP/Chair, Scientific Council, Global Clinical Development, Regeneron
Novel transgenic/chemogenetic models of oxidative stress in the cardiovascular system Dr. Michel’s seminar will discuss the development and application of chemogenetic approaches to dynamically modulate tissue-specific oxidative stress. These studies have yielded new models of heart failure, neurodegeneration, and aortic … Read More
Itaconate suppresses atherosclerosis by activating a Nrf2-dependent anti-inflammatory response in macrophages in mice. https://www.jci.org/articles/view/173034 Group 2 members: Victoria MilosekKelsey WattsNareen Anwar
Extracellular vesicle-mediated communication in cardiovascular disease Extracellular vesicles (EVs) are produced by cells in the cardiovascular system, and they can be taken up by recipient cells to alter function. The contents and functions of EVs change during disease, and they … Read More
Trainees should prepare a 3-4 minute introduction about themselves and their project—no slides! Also, remember that the audience will be quiet diverse from 2nd year graduate students just getting into labs to faculty and also from very different areas. These … Read More
Iron regulation of tissue perfusion Both iron deficiency (ID) and endothelial dysfunction are associated with chronic diseases such as heart failure and chronic kidney disease (CKD). However, how iron regulates endothelial functions remains largely unstudied. Iron deficiency can be categorized … Read More
A trainee is randomly selected (by pulling a name from a jar) to give a 5-6 minute summary of their research project without slides indicating why their project is important, what has been done so far, what needs to be … Read More
Alex Clark - Systems analysis of gene regulatory networks driving cardiomyocyte identity Madeline Jackson - The role of Cx37 in lymphatic valve formation
Transgenic Rabbits for Cardiovascular Research and Drug Development Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. Genome-wide association studies are powerful epidemiological tools to find genes and variants associated with CVD while follow-up biological studies allow … Read More
