A trainee is randomly selected (by pulling a name from a jar) to give a 5-6 minute summary of their research project without slides indicating why their project is important, what has been done so far, what needs to be … Read More
Alex Clark - Systems analysis of gene regulatory networks driving cardiomyocyte identity Madeline Jackson - The role of Cx37 in lymphatic valve formation
Transgenic Rabbits for Cardiovascular Research and Drug Development Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality worldwide. Genome-wide association studies are powerful epidemiological tools to find genes and variants associated with CVD while follow-up biological studies allow … Read More
Cavitation Facilitated AAV Transduction This presentation will focus on multidisciplinary collaborative studies between CVRC and BME that investigating how ultrasound cavitation of microbubble contrast agents can produce site-targeted augmentation of AAV to the heart. These studies are intended to optimize … Read More
Follistatin mediates MASLD and MASH during hepatic insulin resistance on a high fructose diet MASLD (metabolic dysfunction-associated steatotic liver disease) and its progression to steatohepatitis (MASH) correlates with IR (insulin resistance). However, mice with complete hepatic IR owing to hepatic … Read More
Kelsey - Identification of sex dimorphisms in Endothelial-to-Mesenchymal Transition (endoMT) regulation in atherosclerotic disease Randall - Caveolin nanodiscs to investigate Cav-1 scaffolding Kaitlyn - Systems approaches identify drugs and genes regulating cardiomyocyte proliferation
From Data to Discovery: The Role of AI in Transforming Healthcare Research This talk will focus on the current and future role of AI tools in medical research, highlighting the subtleties of leveraging this powerful tool to increase efficiency and … Read More
Understanding Vascular Growth Kinetics At the structural level, the vascular system is a network of interconnected tubes responsible for delivering oxygen and nutrients throughout the body. While accurate, this portrayal understates the complexities inherent to its functionality. Beyond mere transportation, … Read More
Cell-specific LRP1 signaling in acute myocardial infarction Improving the treatment of acute myocardial infarction (AMI) to prevent heart failure (HF) and death remains an urgent unmet medical need. The AHA estimates that every 42 seconds an American will have an … Read More
Presenters - Katie Pavelec, Wyatt Schug, Maddie Jackson, and Skylar Loeb The paper is entitled: Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target https://www.sciencedirect.com/science/article/abs/pii/S0092867424010924?fr=RR-2&ref=pdf_download&rr=8d7d9c9dfbfbc97d
RMB CVRC & School of Medicine MPBP Seminar Role of extracellular myeloperoxidase in atherosclerosis development and late-stage pathogenesis Atherosclerosis is a chronic inflammatory disease whose clinical complications, including major adverse cardiovascular events (MACE) such as myocardial infarction (MI) and stroke, … Read More
