Robin A. Felder
- Phone: 924-5151
Primary Appointment
Professor, Pathology
Education
- PhD, Georgetown University
Research Disciplines
Biochemistry, Bioinformatics and Genomics, Biophysics, Biotechnology, Cardiovascular Biology, Computational Biology, Epigenetics, Experimental Pathology, Genetics, Molecular Biology, Molecular Pharmacology, Physiology, Structural Biology, Translational Science
Research Interests
Clinical Chemistry and Toxicology. Medical Automation Research. Neurotransmitters, cell surface receptors and intracellular second messengers.
Research Description
Personal Statement
Selected Publications
2023
Amatya, B., Yang, S., Yu, P., de Castro, P. A. S. V., Armando, I., Zeng, C., . . . Lee, H. (2023). Peroxiredoxin-4 and Dopamine D5 Receptor Interact to Reduce Oxidative Stress and Inflammation in the Kidney. ANTIOXIDANTS & REDOX SIGNALING, 38(16), 1150-1166. doi:10.1089/ars.2022.0034
Xiao, L., Matharoo, J., Chi, J., Ma, J., Chen, M., Manley, B., . . . Li, X. (2023). Transient depletion of macrophages alters local inflammatory response at the site of disc herniation in a transgenic mouse model. OSTEOARTHRITIS AND CARTILAGE, 31(7), 894-907. doi:10.1016/j.joca.2023.01.574
Twum, S., Fosu, K., Felder, R. A., & Sarpong, K. A. N. (2023). Bridging the gaps in newborn screening programmes: Challenges and opportunities to detect in Africa. AFRICAN JOURNAL OF LABORATORY MEDICINE, 12(1). doi:10.4102/ajlm.v12i1.2225
2022
Gildea, J. J., Xu, P., Schiermeyer, K. A., Yue, W., Carey, R. M., Jose, P. A., & Felder, R. A. (2022). Inverse Salt Sensitivity of Blood Pressure Is Associated with an Increased Renin-Angiotensin System Activity. BIOMEDICINES, 10(11). doi:10.3390/biomedicines10112811
Felder, R. A., Gildea, J. J., Xu, P., Yue, W., Armando, I., Carey, R. M., & Jose, P. A. (2022). Inverse Salt Sensitivity of Blood Pressure: Mechanisms and Potential Relevance for Prevention of Cardiovascular Disease. CURRENT HYPERTENSION REPORTS, 24(9), 361-374. doi:10.1007/s11906-022-01201-9
Xiao, L., Huang, R., Sulimai, N., Yao, R., Manley, B., Xu, P., . . . Li, X. (2022). Amine Functionalized Trimetallic Nitride Endohedral Fullerenes: A Class of Nanoparticle to Tackle Low Back/Leg Pain. ACS APPLIED BIO MATERIALS, 5(6), 2943-2955. doi:10.1021/acsabm.2c00269
Xu, P., Sudarikova, A. V., Ilatovskaya, D. V., Gildea, J. J., Akhter, M., Carey, R. M., . . . Felder, R. A. (2022). Epithelial Sodium Channel Alpha Subunit (αENaC) Is Associated with Inverse Salt Sensitivity of Blood Pressure. BIOMEDICINES, 10(5). doi:10.3390/biomedicines10050981
2021
Kaczmarczyk, J. A., Roberts, R. R., Luke, B. T., Chan, K. C., Van Wagoner, C. M., Felder, R. A., . . . Blonder, J. (2021). Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells.. Oncotarget, 12(20), 2022-2038. doi:10.18632/oncotarget.28072
Lee, H., Jiang, X., Perwaiz, I., Yu, P., Wang, J., Wang, Y., . . . Jose, P. A. (2021). Dopamine D5 receptor-mediated decreases in mitochondrial reactive oxygen species production are cAMP and autophagy dependent. HYPERTENSION RESEARCH, 44(6), 628-641. doi:10.1038/s41440-021-00646-w
Amatya, B., Lee, H., Asico, L. D., Konkalmatt, P., Armando, I., Felder, R. A., & Jose, P. A. (2021). SNX-PXA-RGS-PXC Subfamily of SNXs in the Regulation of Receptor-Mediated Signaling and Membrane Trafficking. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(5). doi:10.3390/ijms22052319
Yue, W., Tran, H. T., Wang, J. -P., Schiermeyer, K., Gildea, J. J., Xu, P., & Felder, R. A. (2021). The Hypertension Related Gene G-Protein Coupled Receptor Kinase 4 Contributes to Breast Cancer Proliferation.. Breast cancer : basic and clinical research, 15, 11782234211015753. doi:10.1177/11782234211015753
2020
Chin, A. C., Gao, Z., Riley, A. M., Furkert, D., Wittwer, C., Dutta, A., . . . Fu, C. (2020). The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α. SCIENCE ADVANCES, 6(44). doi:10.1126/sciadv.abb8542
Yang, J., Asico, L. D., Beitelshees, A. L., Feranil, J. B., Wang, X., Jones, J. E., . . . Villar, V. A. M. (2020). Sorting nexin 1 loss results in increased oxidative stress and hypertension. FASEB JOURNAL, 34(6), 7941-7957. doi:10.1096/fj.201902448R
Tiu, A. C., Yang, J., Asico, L. D., Konkalmatt, P., Zheng, X., Cuevas, S., . . . Villar, V. A. M. (2020). Lipid rafts are required for effective renal D1 dopamine receptor function. FASEB JOURNAL, 34(5), 6999-7017. doi:10.1096/fj.201902710RR
Xu, P., Gildea, J. J., Zhang, C., Konkalmatt, P., Santiago, S., Wang, D. B., . . . Felder, R. A. (2020). Stomach gastrin is regulated by sodium via PPAR-α and dopamine D1 receptor. JOURNAL OF MOLECULAR ENDOCRINOLOGY, 64(2), 53-65. doi:10.1530/JME-19-0053
2019
Han, F., Konkalmatt, P., Mokashi, C., Kumar, M., Zhang, Y., Ko, A., . . . Armando, I. (2019). Dopamine D2 receptor modulates Wnt expression and control of cell proliferation. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-52528-4
Gildea, J. J., Xu, P., Kemp, B. A., Carey, R. M., Jose, P. A., & Felder, R. A. (2019). The Dopamine D1 Receptor and Angiotensin II Type-2 Receptor are Required for Inhibition of Sodium Transport Through a Protein Phosphatase 2A Pathway. HYPERTENSION, 73(6), 1258-1265. doi:10.1161/HYPERTENSIONAHA.119.12705
2018
Gildea, J. J., Xu, P., Kemp, B. A., Carlson, J. M., Tran, H. T., Wang, D. B., . . . Felder, R. A. (2018). Sodium bicarbonate cotransporter NBCe2 gene variants increase sodium and bicarbonate transport in human renal proximal tubule cells. PLOS ONE, 13(4). doi:10.1371/journal.pone.0189464
2017
Li, F., Yang, J., Villar, V. A. M., Asico, L. D., Ma, X., Armando, I., . . . Wang, X. (2018). Loss of renal SNX5 results in impaired IDE activity and insulin resistance in mice. DIABETOLOGIA, 61(3), 727-737. doi:10.1007/s00125-017-4482-1
Genzen, J. R., Burnham, C. -A. D., Felder, R. A., Hawker, C. D., Lippi, G., & Palmer, O. M. P. (2018). Challenges and Opportunities in Implementing Total Laboratory Automation. CLINICAL CHEMISTRY, 64(2), 259-264. doi:10.1373/clinchem.2017.274068
Yatabe, M. S., Iwahori, T., Watanabe, A., Takano, K., Sanada, H., Watanabe, T., . . . Yatabe, J. (2017). Urinary Sodium-to-Potassium Ratio Tracks the Changes in Salt Intake during an Experimental Feeding Study Using Standardized Low-Salt and High-Salt Meals among Healthy Japanese Volunteers. NUTRIENTS, 9(9). doi:10.3390/nu9090951
Gildea, J. J., Van Sciver, R. E., McGrath, H. E., Kemp, B. A., Jose, P. A., Carey, R. M., & Felder, R. A. (2017). Dopaminergic Immunofluorescence Studies in Kidney Tissue. HYPERTENSION: METHODS AND PROTOCOLS, 1527, 151-161. doi:10.1007/978-1-4939-6625-7_12
2016
Jiang, X., Zhang, Y., Yang, Y., Yang, J., Asico, L. D., Chen, W., . . . Yang, Z. (2017). Gastrin stimulates renal dopamine production by increasing the renal tubular uptake of L-DOPA. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 312(1), E1-E10. doi:10.1152/ajpendo.00116.2016
Felder, R. A., Jose, P. A., Xu, P., & Gildea, J. J. (2016). The Renal Sodium Bicarbonate Cotransporter NBCe2: Is It a Major Contributor to Sodium and pH Homeostasis?. CURRENT HYPERTENSION REPORTS, 18(9). doi:10.1007/s11906-016-0679-9
Jose, P. A., Felder, R. A., Yang, Z., Zeng, C., & Eisner, G. M. (2016). Gastrorenal Axis. HYPERTENSION, 67(6), 1056-1063. doi:10.1161/HYPERTENSIONAHA.115.06424
Villar, V. A. M., Zheng, C., Konkalmatt, P., Wang, X., Asico, L. D., Felder, R. A., . . . Jose, P. A. (2016). Differential HDAC class 1 isoenzyme regulation of blood pressure. Journal of the American Society of Hypertension, 10(4), e54. doi:10.1016/j.jash.2016.03.132
Jose, P. A., Yang, Z., Zeng, C., & Felder, R. A. (2016). The importance of the gastrorenal axis in the control of body sodium homeostasis. EXPERIMENTAL PHYSIOLOGY, 101(4), 465-470. doi:10.1113/EP085286
Jiang, X., Chen, W., Liu, X., Wang, Z., Liu, Y., Felder, R. A., . . . Yang, Z. (2016). The Synergistic Roles of Cholecystokinin B and Dopamine D5 Receptors on the Regulation of Renal Sodium Excretion. PLOS ONE, 11(1). doi:10.1371/journal.pone.0146641
2015
Wang, Z., Zeng, C., Villar, V. A. M., Chen, S. -Y., Konkalmatt, P., Wang, X., . . . Jose, P. A. (2016). Human GRK4γ142V Variant Promotes Angiotensin II Type I Receptor-Mediated Hypertension via Renal Histone Deacetylase Type 1 Inhibition. HYPERTENSION, 67(2), 325-334. doi:10.1161/HYPERTENSIONAHA.115.05962
Gildea, J. J., Xu, P., Carlson, J. M., Gaglione, R. T., Wang, D. B., Kemp, B. A., . . . Felder, R. A. (2015). The sodium-bicarbonate cotransporter NBCe2 (slc4a5) expressed in human renal proximal tubules shows increased apical expression under high-salt conditions. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 309(11), R1447-R1459. doi:10.1152/ajpregu.00150.2015
Villar, V. A. M., Yang, J., Asico, L. D., Feranil, J. B., Wang, X., Jones, J. E., . . . Jose, P. A. (2015). Increased oxidative stress and hypertension in Snx1 knockout mice. Journal of the American Society of Hypertension, 9(4), e83. doi:10.1016/j.jash.2015.03.198
Li, F., Yang, J., Jones, J. E., Villar, V. A. M., Yu, P., Armando, I., . . . Jose, P. A. (2015). Sorting Nexin 5 and Dopamine D1 Receptor Regulate the Expression of the Insulin Receptor in Human Renal Proximal Tubule Cells. ENDOCRINOLOGY, 156(6), 2211-2221. doi:10.1210/en.2014-1638
Han, F., Konkalmatt, P., Chen, J., Gildea, J., Felder, R. A., Jose, P. A., & Armando, I. (2015). miR-217 Mediates the Protective Effects of the Dopamine D2 Receptor on Fibrosis in Human Renal Proximal Tubule Cells. HYPERTENSION, 65(5), 1118-U856. doi:10.1161/HYPERTENSIONAHA.114.05096
Sanada, H., Yoneda, M., Yatabe, J., Williams, S. M., Bartlett, J., White, M. J., . . . Jose, P. A. (2016). Common variants of the G protein-coupled receptor type 4 are associated with human essential hypertension and predict the blood pressure response to angiotensin receptor blockade. PHARMACOGENOMICS JOURNAL, 16(1), 3-9. doi:10.1038/tpj.2015.6
2014
Sanada, H., Yokokawa, H., Yatabe, J., Williams, S. M., Felder, R. A., Jose, P. A., & Takenosita, S. (2014). Association between lifestyle-related disorders and visceral fat mass in Japanese males: a hospital based cross-sectional study. ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE, 19(6), 429-435. doi:10.1007/s12199-014-0411-9
Armando, I., Konkalmatt, P., Felder, R. A., & Jose, P. A. (2015). The renal dopaminergic system: novel diagnostic Cross Mark and therapeutic approaches in hypertension and kidney disease. TRANSLATIONAL RESEARCH, 165(4), 505-511. doi:10.1016/j.trsl.2014.07.006
Yu, P., Sun, M., Villar, V. A. M., Zhang, Y., Weinman, E. J., Felder, R. A., & Jose, P. A. (2014). Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells. CELLULAR SIGNALLING, 26(11), 2521-2529. doi:10.1016/j.cellsig.2014.07.003
Gildea, J. J., Seaton, J. E., Victor, K. G., Reyes, C. M., Wang, D. B., Pettigrew, A. C., . . . Felder, R. A. (2014). Exosomal transfer from human renal proximal tubule cells to distal tubule and collecting duct cells. CLINICAL BIOCHEMISTRY, 47(15), 89-94. doi:10.1016/j.clinbiochem.2014.06.018
Felder, R. A., Jackson, K. D., & Walter, A. M. (2014). Process Evaluation of an Open Architecture Real-Time Molecular Laboratory Platform. JALA, 19(5), 468-473. doi:10.1177/2211068214533195
Han, F., Konkalmatt, P., Gildea, J., Jones, J. E., Felder, R. A., Jose, P. A., & Armando, I. (2014). Single nucleotide polymorphisms of the dopamine D2 receptor increase inflammation and fibrosis in human renal proximal tubule cells. Journal of the American Society of Hypertension, 8(4), e3. doi:10.1016/j.jash.2014.03.010
Gildea, J. J., Shah, I. T., Van Sciver, R. E., Israel, J. A., Enzensperger, C., McGrath, H. E., . . . Felder, R. A. (2014). The cooperative roles of the dopamine receptors, D1R and D5R, on the regulation of renal sodium transport. KIDNEY INTERNATIONAL, 86(1), 118-126. doi:10.1038/ki.2014.5
Felder, R. A. (2014). Automated Specimen Inspection, Quality Analysis, and Its Impact on Patient Safety: Beyond the Bar Code. CLINICAL CHEMISTRY, 60(3), 433-434. doi:10.1373/clinchem.2013.219352
Yu, P., Han, W., Villar, V. A. M., Yang, Y., Lu, Q., Lee, H., . . . Jose, P. A. (2014). Unique role of NADPH oxidase 5 in oxidative stress in human renal proximal tubule cells. REDOX BIOLOGY, 2, 570-579. doi:10.1016/j.redox.2014.01.020
Kitada, K., Nakano, D., Ohsaki, H., Hitomi, H., Minamino, T., Yatabe, J., . . . Nishiyama, A. (2014). Hyperglycemia causes cellular senescence via a SGLT2-and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy. JOURNAL OF DIABETES AND ITS COMPLICATIONS, 28(5), 604-611. doi:10.1016/j.jdiacomp.2014.05.010
2013
Jiang, X., Konkalmatt, P., Yang, Y., Gildea, J., Jones, J. E., Cuevas, S., . . . Armando, I. (2014). Single-Nucleotide Polymorphisms of the Dopamine D2 Receptor Increase Inflammation and Fibrosis in Human Renal Proximal Tubule Cells. HYPERTENSION, 63(3), E74-E80. doi:10.1161/HYPERTENSIONAHA.113.02569
Armando, I., Villar, V. A. M., Jones, J. E., Lee, H., Wang, X., Asico, L. D., . . . Jose, P. A. (2014). Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation. FASEB JOURNAL, 28(3), 1422-1434. doi:10.1096/fj.13-243840
Lee, H., Abe, Y., Lee, I., Shrivastav, S., Crusan, A. P., Huettemann, M., . . . Kopp, J. B. (2014). Increased mitochondrial activity in renal proximal tubule cells from young spontaneously hypertensive rats. KIDNEY INTERNATIONAL, 85(3), 561-569. doi:10.1038/ki.2013.397
Yokokawa, H., Goto, A., Sanada, H., Watanabe, T., Felder, R. A., Jose, P. A., & Yasumura, S. (2014). Association between control to target blood pressures and healthy lifestyle factors among Japanese hypertensive patients: Longitudinal data analysis from Fukushima Research of Hypertension (FRESH). OBESITY RESEARCH & CLINICAL PRACTICE, 8(4), E364-E373. doi:10.1016/j.orcp.2013.08.004
Gildea, J. J., Carlson, J. M., Schoeffel, C. D., Carey, R. M., & Felder, R. A. (2013). Urinary exosome miRNome analysis and its applications to salt sensitivity of blood pressure. CLINICAL BIOCHEMISTRY, 46(12), 1131-1134. doi:10.1016/j.clinbiochem.2013.05.052
Gildea, J. J., Tran, H. T., Van Sciver, R. E., Wang, D. B., Carlson, J. M., & Felder, R. A. (2013). A Novel Role for c-Myc in G Protein-Coupled Receptor Kinase 4 (GRK4) Transcriptional Regulation in Human Kidney Proximal Tubule Cells. HYPERTENSION, 61(5), 1021-+. doi:10.1161/HYPERTENSIONAHA.111.00321
Gildea, J. J., Lahiff, D. T., Van Sciver, R. E., Weiss, R. S., Shah, N., McGrath, H. E., . . . Felder, R. A. (2013). A linear relationship between the ex-vivo sodium mediated expression of two sodium regulatory pathways as a surrogate marker of salt sensitivity of blood pressure in exfoliated human renal proximal tubule cells: The virtual renal biopsy. CLINICA CHIMICA ACTA, 421, 236-242. doi:10.1016/j.cca.2013.02.021
Gildea, J. J., Wang, X., Shah, N., Tran, H., Spinosa, M., Van Sciver, R., . . . Felder, R. A. (2013). Dopamine and Angiotensin Type 2 Receptors Cooperatively Inhibit Sodium Transport in Human Renal Proximal Tubule Cells (vol 60, pg 396, 2012). HYPERTENSION, 61(1), E7. doi:10.1161/HYP.0b013e31827a7c3b
Gildea, J. J., McGrath, H. E., Van Sciver, R. E., Wang, D. B., & Felder, R. A. (2013). Isolation, growth, and characterization of human renal epithelial cells using traditional and 3D methods.. Methods in molecular biology (Clifton, N.J.), 945, 329-345. doi:10.1007/978-1-62703-125-7_20
Felder, R. A., White, M. J., Williams, S. M., & Jose, P. A. (2013). Diagnostic tools for hypertension and salt sensitivity testing. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 22(1), 65-76. doi:10.1097/MNH.0b013e32835b3693
2012
Villar, V. A. M., Jones, J. E., Armando, I., Asico, L. D., Escano, C. S. J., Lee, H., . . . Jose, P. A. (2013). Sorting Nexin 1 Loss Results in D5 Dopamine Receptor Dysfunction in Human Renal Proximal Tubule Cells and Hypertension in Mice. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(1), 152-163. doi:10.1074/jbc.M112.428458
Carey, R. M., Schoeffel, C. D., Gildea, J. J., Jones, J. E., McGrath, H. E., Gordon, L. N., . . . Felder, R. A. (2012). Salt Sensitivity of Blood Pressure Is Associated With Polymorphisms in the Sodium-Bicarbonate Cotransporter. HYPERTENSION, 60(5), 1359-+. doi:10.1161/HYPERTENSIONAHA.112.196071
Yokokawa, H., Goto, A., Sanada, H., Watanabe, T., Felder, R. A., Jose, P. A., & Yasumura, S. (2012). 192 ACHIEVEMENT STATUS TOWARD GOAL BLOOD PRESSURE LEVELS AND HEALTHY LIFESTYLES AMONG JAPANESE HYPERTENSIVE PATIENTS; LONGITUDINAL DATA ANALYSIS FROM FUKUSHIMA RESEARCH OF HYPERTENSION (FRESH). Journal of Hypertension, 30(Supplement 1), e57. doi:10.1097/01.hjh.0000420016.07716.f2
Gildea, J. J., Wang, X., Shah, N., Tran, H., Spinosa, M., Van Sciver, R., . . . Felder, R. A. (2012). Dopamine and Angiotensin Type 2 Receptors Cooperatively Inhibit Sodium Transport in Human Renal Proximal Tubule Cells. HYPERTENSION, 60(2), 396-+. doi:10.1161/HYPERTENSIONAHA.112.194175
Yang, Y., Zhang, Y., Cuevas, S., Villar, V. A., Escano, C., Asico, L. D., . . . Jose, P. A. (2012). Paraoxonase 2 decreases renal reactive oxygen species production, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of NADPH oxidase. FREE RADICAL BIOLOGY AND MEDICINE, 53(3), 437-446. doi:10.1016/j.freeradbiomed.2012.05.015
Yatabe, J., Yatabe, M. S., Yoneda, M., Felder, R. A., Jose, P. A., & Sanada, H. (2012). Hypertension-Related Gene Polymorphisms of G-Protein-Coupled Receptor Kinase 4 Are Associated with NT-proBNP Concentration in Normotensive Healthy Adults. INTERNATIONAL JOURNAL OF HYPERTENSION, 2012. doi:10.1155/2012/806810
Sanada, H., Yokokawa, H., Yoneda, M., Yatabe, J., Yatabe, M. S., Williams, S. M., . . . Jose, P. A. (2012). High Body Mass Index is an Important Risk Factor for the Development of Type 2 Diabetes. INTERNAL MEDICINE, 51(14), 1821-1826. doi:10.2169/internalmedicine.51.7410
2011
Yu, P., Han, W., Zhang, Y., Villar, V. A. M., Li, H., Felder, R. E. A., . . . Yu, P. (2011). NADPH Oxidase 5 May Play a Role in Human Essential Hypertension. Free Radical Biology and Medicine, 51, S53. doi:10.1016/j.freeradbiomed.2011.10.136
Felder, R. A. (2011). Preanalytical Errors Introduced by Sample-Transportation Systems: A Means to Assess Them. CLINICAL CHEMISTRY, 57(10), 1349-1350. doi:10.1373/clinchem.2011.172452
Yatabe, J., Yoneda, M., Yatabe, M. S., Watanabe, T., Felder, R. A., Jose, P. A., & Sanada, H. (2011). Angiotensin III Stimulates Aldosterone Secretion from Adrenal Gland Partially via Angiotensin II Type 2 Receptor But Not Angiotensin II Type 1 Receptor. ENDOCRINOLOGY, 152(4), 1582-1588. doi:10.1210/en.2010-1070
Gildea, J. J., Kemp, B. A., Howell, N. L., Van Sciver, R. E., Carey, R. M., & Felder, R. A. (2011). Inhibition of renal caveolin-1 reduces natriuresis and produces hypertension in sodium-loaded rats. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 300(4), F914-F920. doi:10.1152/ajprenal.00380.2010
Yokokawa, H., Goto, A., Sanada, H., Watanabe, T., Felder, R. A., Jose, P. A., & Yasumura, S. (2011). Achievement Status toward Goal Blood Pressure Levels and Healthy Lifestyles among Japanese Hypertensive Patients; Cross-sectional Survey Results from Fukushima Research of Hypertension (FRESH). INTERNAL MEDICINE, 50(11), 1149-1156. doi:10.2169/internalmedicine.50.4969
2010
Fan, Y. -Y., Kohno, M., Hitomi, H., Kitada, K., Fujisawa, Y., Yatabe, J., . . . Nakano, D. (2011). Aldosterone/Mineralocorticoid Receptor Stimulation Induces Cellular Senescence in the Kidney. ENDOCRINOLOGY, 152(2), 680-688. doi:10.1210/en.2010-0829
Yu, P., Han, W., Villar, V. A. M., Li, H., Arnaldo, F. B., Concepcion, G. P., . . . Jose, P. A. (2011). Dopamine D1 receptor-mediated inhibition of NADPH oxidase activity in human kidney cells occurs via protein kinase A-protein kinase C cross talk. FREE RADICAL BIOLOGY AND MEDICINE, 50(7), 832-840. doi:10.1016/j.freeradbiomed.2010.12.027
Yokokawa, H., Sanada, H., Goto, A., Watanabe, T., Felder, R. A., Jose, P. A., . . . Yasumura, S. (2010). Characteristics of Antihypertensive Medication and Change of Prescription Over 1 Year of Follow-Up in Japan: Fukushima Research of Hypertension (FRESH). AMERICAN JOURNAL OF HYPERTENSION, 23(12), 1299-1305. doi:10.1038/ajh.2010.175
Gildea, J. J., Shah, I., Weiss, R., Casscells, N. D., McGrath, H. E., Zhang, J., & Felder, R. A. (2010). HK-2 Human Renal Proximal Tubule Cells as a Model for G Protein-Coupled Receptor Kinase Type 4-Mediated Dopamine 1 Receptor Uncoupling. HYPERTENSION, 56(3), 505-511. doi:10.1161/HYPERTENSIONAHA.110.152256
Yatabe, M. S., Yatabe, J., Yoneda, M., Watanabe, T., Otsuki, M., Felder, R. A., . . . Sanada, H. (2010). Salt sensitivity is associated with insulin resistance, sympathetic overactivity, and decreased suppression of circulating renin activity in lean patients with essential hypertension. AMERICAN JOURNAL OF CLINICAL NUTRITION, 92(1), 77-82. doi:10.3945/ajcn.2009.29028
Jose, P. A., Soares-da-Silva, P., Eisner, G. M., & Felder, R. A. (2010). Dopamine and G protein-coupled receptor kinase 4 in the kidney: Role in blood pressure regulation. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1802(12), 1259-1267. doi:10.1016/j.bbadis.2010.02.004
Li, H., Yu, P., Sun, Y., Felder, R. A., Periasamy, A., & Jose, P. A. (2010). Actin cytoskeleton-dependent Rab GTPase-regulated angiotensin type I receptor lysosomal degradation studied by fluorescence lifetime imaging microscopy. JOURNAL OF BIOMEDICAL OPTICS, 15(5). doi:10.1117/1.3484751