CVRC Director Gary Owens, PhD, presented this year’s Robert M. Berne Lecture on May 21. The lecture, in memory of the CVRC’s founder, Robert M. Berne, MD, is a prestigious lecture. Since the first presentation in 1990, the presentation has been given by 5 Nobel Laureates and over 20 members of the National Academy of Science. “This lecture is one of the most beautiful events in our cardiovascular community,” said Brant Isakson, PhD, during his introduction of Owens. Owens is a fitting addition to the storied list of Berne Lecturers not only for his leadership of the CVRC, but for his research and influence at UVA. Owens has published over 230 papers, receiving over 46,000 citations. He also reformed UVA’s MD/PhD education program and has been instrumental in building the CVRC’s relationship with AstraZeneca.
Owens gave a broad overview of the current research avenues in his research group, which is largely focused on understanding atherosclerosis. Atherosclerosis is a condition where fatty deposits accumulate in the blood vessels. The body naturally forms a fibrous cap over these deposits, but the thickness of that cap can vary. A thin cap is liable to break, releasing the fats and dying cells into the bloodstream, causing a heart attack or stroke. A thick cap is much more stable. Owens and his team are interested in understanding why these cap thicknesses vary and how controlling inflammation can contribute to better patient outcomes.
Owens’ talk was attended by the UVA cardiovascular community, including 29 Owens Lab members, past and present. His children and grandchildren also attended. “It was a privilege to hear this lecture from someone whose career has so profoundly shaped the field and this institution,” says Isakson. Owens was presented with a plaque and Jefferson Cup in thanks for his lecture and service to the community.

Owens (right) receives a plaque and Jefferson Cup from Isakson (left).
