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Mingxia Gu, MD, PhD, FAHA
Hosted by: Bowen Wang, PhD
March 16, 2023 @ 11:00 am – 12:00 pm
Reconstructing Organotypic Vasculature in a Dish: Towards Therapeutic Discovery and Precision Medicine
Capillary endothelial cells are highly specialized in different organ systems at both molecular and functional levels. However, the factors driving endothelial cell fate determination remains unknown. In this talk, I will introduce how we differentiated organ-specific endothelium in heart and lung from iPSCs, and how we used these stem cell models to study the role of vascular defect in the etiology of cardiopulmonary diseases.
Affiliation: Assistant Professor, Center for Stem Cell & Organoid Medicine (CuSTOM), Divisions of Pulmonary Biology, Molecular Cardiovascular Biology, and Developmental Biology Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati OH