Craig H. Meyer

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Primary Appointment

Professor, Biomedical Engineering

Research Disciplines

Cardiovascular Biology, Translational Science

Research Interests

Magnetic Resonance Imaging

Research Description

Our research focuses on inventing, developing and applying new magnetic resonance imaging (MRI) techniques, especially techniques that acquire the image data very rapidly. This work involves MRI physics, signal processing, and image reconstruction techniques. Rapid MRI acquisition is particularly important for cardiac studies, because of cardiac and respiratory motion. One focus of our research is imaging atherosclerosis in arteries and its effects on perfusion of the heart, brain, and legs. In much of our research, we work with industrial collaborators with the goal of making our techniques widely available.
We collaborate with other labs at the University of Virginia on a variety of projects. One such collaboration is focused on developing new contrast agents and imaging methods for molecular and cellular imaging of cardiovascular inflammation. Another collaboration is focused on developing image-based models of musculoskeletal disease. We are also studying peripheral arterial disease through a set of MRI methods and developing new methods of characterizing heart failure. In collaboration with the hyperpolarized gas MRI group, we are developing fast methods of imaging the lung.

Personal Statement

Our research focuses on inventing, developing and applying new magnetic resonance imaging (MRI) techniques, especially techniques that acquire the image data very rapidly. This work involves MRI physics, signal processing, and image reconstruction techniques. Rapid MRI acquisition is particularly important for cardiac studies, because of cardiac and respiratory motion. One focus of our research is imaging atherosclerosis in arteries and its effects on perfusion of the heart, brain, and legs. In much of our research, we work with industrial collaborators with the goal of making our techniques widely available.
We collaborate with other labs at the University of Virginia on a variety of projects. One such collaboration is focused on developing new contrast agents and imaging methods for molecular and cellular imaging of cardiovascular inflammation. Another collaboration is focused on developing image-based models of musculoskeletal disease. We are also studying peripheral arterial disease through a set of MRI methods and developing new methods of characterizing heart failure. In collaboration with the hyperpolarized gas MRI group, we are developing fast methods of imaging the lung.

Training

  • Basic Cardiovascular Research Training Grant

Selected Publications

Salerno M, Taylor A, Yang Y, Kuruvilla S, Ragosta M, Meyer CH, Kramer CM, Adenosine stress cardiovascular magnetic resonance with variable-density spiral pulse sequences accurately detects coronary artery disease: initial clinical evaluation., 2014; Circulation. Cardiovascular imaging. 7(4) 639-46. PMID: 24759900 | PMCID: PMC4102611

Jiji RS, Pollak AW, Epstein FH, Antkowiak PF, Meyer CH, Weltman AL, Lopez D, Dimaria JM, Hunter JR, Christopher JM, Kramer CM, Reproducibility of rest and exercise stress contrast-enhanced calf perfusion magnetic resonance imaging in peripheral arterial disease., 2013; Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 15() 14. PMID: 23343398 | PMCID: PMC3562222

Pollak AW, Meyer CH, Epstein FH, Jiji RS, Hunter JR, Dimaria JM, Christopher JM, Kramer CM, Arterial spin labeling MR imaging reproducibly measures peak-exercise calf muscle perfusion: a study in patients with peripheral arterial disease and healthy volunteers., 2012; JACC. Cardiovascular imaging. 5(12) 1224-30. PMID: 23236972 | PMCID: PMC3531823

Pallas A, Meyer CH, Mojon D, [Nintendo 3DS : Technology, physiology and possible risks for children's eyes.], 2012; Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft. () . PMID: 23224123

Clemens CR, Bertelmann T, Meyer CH, Vitreous traction after ozurdex injection., 2012; Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 29(1) 3-4. PMID: 23098563

Saxena S, Jain A, Ramindar Sharma S, Meyer CH, Three-dimensional spectral domain optical coherence tomography of retina in choroidal metastasis due to uterine endometrial carcinoma., 2012; BMJ case reports. 2012() . PMID: 22967681

Meyer CH, Klein A, Alten F, Liu Z, Stanzel BV, Helb HM, Brinkmann CK, Release and velocity of micronized dexamethasone implants with an intravitreal drug delivery system: kinematic analysis with a high-speed camera., 2012; Retina (Philadelphia, Pa.). 32(10) 2133-40. PMID: 23060033

Feng X, Salerno M, Kramer CM, Meyer CH, Kalman filter techniques for accelerated Cartesian dynamic cardiac imaging., 2012; Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. () . PMID: 22926804 | PMCID: PMC3536913

Krohne TU, Liu Z, Holz FG, Meyer CH, Intraocular pharmacokinetics of ranibizumab following a single intravitreal injection in humans., 2012; American journal of ophthalmology. 154(4) 682-686.e2. PMID: 22818800