Antonio Abbate

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Primary Appointment

Ruth C. Heede Professor of Cardiology, Medicine- Cardiovascular Medicine

Education

  • MD, Medical School, University Campus Bio-Medico, Rome, Italy
  • Residency, Cardiovascular Medicine, Catholic University of the Sacred Heart, Rome, Italy
  • Residency, Internal Medicine, Virginia Commonwealth University, Richmond, VA
  • PhD, Molecular and Cellular Cardiology, Catholic University of the Sacred Heart, Rome, Italy

Research Disciplines

Cardiovascular Biology, Immunology

Research Interests

Identifying and exploring the role of innate immunity, inflammasome, and interleukin-1 blockade in the pathogenesis and pathophysiology of cardiovascular disease

Research Description

Dr. Abbate and his team collaborate on, develop, and execute bench-to-bedside research exploring the impact of innate immunity and its role in cardiovascular disease and injury (ischemia, reperfusion, infection, heart failure, etc.). They are recognized for their translational work on Interleukin-1 and inflammasome-targeted treatments for acute myocardial infarction, heart failure, pericarditis, and myocarditis.

Personal Statement

Dr. Antonio Abbate, cardiologist researcher, joined University of Virginia as the Ruth C. Heede Professor of Cardiology in the Robert M. Berne Cardiovascular Research Center in July 2022. Prior to his arrival at UVA, Dr. Abbate spent 15 years as an attending physician at Virginia Commonwealth University (VCU) where he was promoted to the rank of Professor of Medicine as the James C. Roberts, Esq. Professor of Cardiology in the VCU Pauley Heart Center. During his time at VCU, Dr. Abbate served as Vice Chair of the Division of Cardiology, Medical Director of the Clinical Research Unit, Associate Chair for Research in the Department of Internal Medicine, Associate Director of the Wright Center for Clinical and Translational Research and received the inaugural Thames-Kontos Distinguished Mentor Award from the School of Medicine at VCU. Named among the Top Cardiologists in the country by Forbes Magazine, Dr. Abbate is board certified in Internal Medicine, Cardiovascular Medicine, and Cardio-Oncology, and a Fellow of the American College of Cardiology, American Heart Association, and European Society of Cardiology. Dr. Abbate has contributed to hundreds of peer-reviewed publications related to his investigator-initiated research on Interleukin-1 and inflammation in cardiovascular diseases, and his research has been funded by the National Institutes of Health, the American Heart Association, and various industry sponsors.

Selected Publications

2024

Naya, N. M., Toldo, S., & Abbate, A. (2024). Colchicine Leads the Charge in Post-percutaneous Coronary Intervention Anti-inflammatory Defense. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 83(3), 231-233. doi:10.1097/FJC.0000000000001523

Golino, M., Harding, D., Del Buono, M. G., Fanti, S., Mohiddin, S., Toldo, S., . . . Abbate, A. (2024). Innate and adaptive immunity in acute myocarditis.. International journal of cardiology, 131901. doi:10.1016/j.ijcard.2024.131901

Golino, M., Corna, G., De Ponti, R., Abbate, A., & Van Tassell, B. (2024). One-year outcomes of patients with ST-segment elevation myocardial infarction according to eosinophil blood count. EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE. doi:10.1093/ehjacc/zuae015

La Vecchia, G., Del Buono, M. G., Bonaventura, A., Vecchiè, A., Moroni, F., Cartella, I., . . . Abbate, A. (2024). Cardiac Involvement in Patients With Multisystem Inflammatory Syndrome in Adults.. Journal of the American Heart Association, 13(4), e032143. doi:10.1161/jaha.123.032143

Vecchié, A., Bonaventura, A., Golino, M., Thomas, G., & Abbate, A. (2024). Novel therapeutic insights into the treatment of pericarditis: Targeting the innate immune system.. Journal of cardiovascular pharmacology. doi:10.1097/fjc.0000000000001553

Palazzuoli, A., Ruocco, G., Del Buono, M. G., Pavoncelli, S., Delcuratolo, E., Abbate, A., & Lavie, C. J. (2024). The role and application of current pharmacological management in patients with advanced heart failure. HEART FAILURE REVIEWS, 29(2), 535-548. doi:10.1007/s10741-024-10383-0

Naya, N. M., Kelly, J., Corna, G., Golino, M., Polizio, A. H., Abbate, A., . . . Mezzaroma, E. (2024). An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular Effects. MOLECULES, 29(2). doi:10.3390/molecules29020473

Desai, A. K., Betz, Y., & Abbate, A. (2024). Navigating the Uncertainty: A New Score to Guide TAVR in Patients With Chronic Kidney Disease. AMERICAN JOURNAL OF CARDIOLOGY, 211, 365-366. doi:10.1016/j.amjcard.2023.11.030

Van Tassell, B., Talasaz, A. H., Redlich, G., Ziegelaar, B., & Abbate, A. (2024). A Real-World Analysis of New-Onset Heart Failure After Anterior Wall ST-Elevation Acute Myocardial Infarction in the United States. AMERICAN JOURNAL OF CARDIOLOGY, 211, 245-250. doi:10.1016/j.amjcard.2023.11.037

Mazza, M., Kotzalidis, G. D., Marano, G., De Berardis, D., Martinotti, G., Romagnoli, E., . . . Sani, G. (2024). Lorcaserin: Worthy of Further Insights? Results from Recent Research. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 23(3), 278-283. doi:10.2174/1871527322666230330124137

2023

Carbone, S., & Abbate, A. (2024). SGLT2 inhibitors in Patients Admitted for Acute Heart Failure: The Earlier the Better. AMERICAN JOURNAL OF CARDIOLOGY, 214, 177-179. doi:10.1016/j.amjcard.2023.12.018

Galli, M., Niccoli, G., De Maria, G., Brugaletta, S., Montone, R. A., Vergallo, R., . . . Crea, F. (2023). Author Correction: Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction.. Nature reviews. Cardiology. doi:10.1038/s41569-023-00974-z

Abbate, A., Weber, B., Garschick, M., Adamo, L., & Beavers, C. (2023). Inflammation and Heart Diseases: Immunology, Cardiology,and Rheumatology.. Journal of cardiovascular pharmacology. doi:10.1097/fjc.0000000000001531

Moroni, F., Corna, G., Del Buono, M. G., Golino, M., Talasaz, A. H., Decotto, S., . . . Abbate, A. (2024). Impact of C-reactive protein levels and role of anakinra in patients with ST-elevation myocardial infarction. INTERNATIONAL JOURNAL OF CARDIOLOGY, 398. doi:10.1016/j.ijcard.2023.131610

Galli, M., Niccoli, G., De Maria, G., Brugaletta, S., Montone, R. A., Vergallo, R., . . . Crea, F. (2023). Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction. NATURE REVIEWS CARDIOLOGY. doi:10.1038/s41569-023-00953-4

Corna, G., Golino, M., Talasaz, A. H., Moroni, F., del Buono, M. G., Damonte, J. I., . . . Abbate, A. (2023). Response to interleukin-1 blockade with anakinra in women and men with ST-segment elevation myocardial infarction. MINERVA CARDIOLOGY AND ANGIOLOGY. doi:10.23736/S2724-5683.23.06439-6

Toldo, S., & Abbate, A. (2024). The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases. NATURE REVIEWS CARDIOLOGY, 21(4), 219-237. doi:10.1038/s41569-023-00946-3

Del Buono, M. G., Bonaventura, A., Vecchie, A., Moroni, F., Golino, M., Bressi, E., . . . Abbate, A. (2024). Pathogenic pathways and therapeutic targets of inflammation in heart diseases: A focus on Interleukin-1. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 54(2). doi:10.1111/eci.14110

Jafree, E., Del Buono, M. G., Canada, J. M., Carbone, S., Kron, J., Arena, R., . . . Trankle, C. R. (2023). Interleukin-1 Inhibition for the Prevention and Treatment of Heart Failure.. Journal of cardiovascular pharmacology. doi:10.1097/fjc.0000000000001497

Cochran, J. D., Yura, Y., Thel, M. C., Doviak, H., Polizio, A. H., Arai, Y., . . . Walsh, K. (2023). Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction. CIRCULATION, 148(15), 1165-1178. doi:10.1161/CIRCULATIONAHA.123.064170

Weber, B. N., Garshick, M., Abbate, A., Youngstein, T., Stewart, G., Bohula, E., . . . Mukherjee, M. (2023). Acute cardiovascular complications of immune-mediated systemic inflammatory diseases. EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, 12(11), 792-801. doi:10.1093/ehjacc/zuad096

Bonaventura, A., & Abbate, A. (2023). Colchicine for cardiovascular prevention: the dawn of a new era has finally come. EUROPEAN HEART JOURNAL, 44(35), 3303-3304. doi:10.1093/eurheartj/ehad453

Golbus, J. R., Gosch, K., Birmingham, M. C., Butler, J., Lingvay, I., Lanfear, D. E., . . . Nallamothu, B. K. (2023). Association Between Wearable Device Measured Activity and Patient-Reported Outcomes for Heart Failure. JACC-HEART FAILURE, 11(11), 1521-1530. doi:10.1016/j.jchf.2023.05.033

Moroni, F., Golino, M., Carbone, S., Trankle, C., Del Buono, M. G., Talasaz, A., . . . Abbate, A. (2023). Interleukin-1 blockade in heart failure: an on-treatment and off-treatment cardiorespiratory fitness analysis. ESC HEART FAILURE, 10(5), 3199-3202. doi:10.1002/ehf2.14460

Myachikova, V. Y., Maslyanskiy, A. L., Moiseeva, O. M., V. Vinogradova, O., V. Gleykina, E., Lavrovsky, Y., . . . Samsonov, M. Y. (2023). Treatment of Idiopathic Recurrent Pericarditis With Goflikicept Phase II/III Study Results. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 82(1). doi:10.1016/j.jacc.2023.04.046

Thomas, G. K., Bonaventura, A., Vecchié, A., van Tassell, B., Imazio, M., Klein, A., . . . Abbate, A. (2023). Interleukin-1 blockers for the treatment of recurrent pericarditis: pathophysiology, patient reported outcomes and perspectives.. Journal of cardiovascular pharmacology. doi:10.1097/fjc.0000000000001435

Lazzerini, P. E., Abbate, A., Boutjdir, M., & Capecchi, P. L. (2023). Fir(e)ing the Rhythm Inflammatory Cytokines and Cardiac Arrhythmias. JACC-BASIC TO TRANSLATIONAL SCIENCE, 8(6), 728-750. doi:10.1016/j.jacbts.2022.12.004

Ahmed, S. I., Bohmke, N. J., Kenyon, J., Billingsley, H. E., Salmons, H., Markley, R., . . . Carbone, S. (2023). Objectively Measured Night-Time Sleep Efficiency and Quality of Life in Patients With Heart Failure With Preserved Ejection Fraction. AMERICAN JOURNAL OF CARDIOLOGY, 208, 124-125. doi:10.1016/j.amjcard.2023.09.050

Golino, M., Moroni, F., & Abbate, A. (2023). Connecting the Dots: Inflammatory Burden and Outcomes in Heart Failure. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 12(19). doi:10.1161/JAHA.123.031786

Corna, G., Golino, M., Moroni, F., Del Buono, M. G., Talasaz, A. H., Decotto, S., . . . Abbate, A. (2023). Report Response to Interleukin-1 Blockade With Anakinra in Black and White Americans With ST-Segment Elevation Myocardial Infarction. AMERICAN JOURNAL OF CARDIOLOGY, 207, 336-338. doi:10.1016/j.amjcard.2023.08.175

Potere, N., Abbate, A., Kanthi, Y., Carrier, M., Toldo, S., Porreca, E., & Di Nisio, M. (2023). Inflammasome Signaling, Thromboinflammation, and Venous Thromboembolism. JACC-BASIC TO TRANSLATIONAL SCIENCE, 8(9). doi:10.1016/j.jacbts.2023.03.017

Kolominsky, J., Poklepovic, A., Syed, A., Robila, V., Rao, K., Tchoukina, I., . . . Kron, J. (2023). Granulomatous Cardiomyopathy Presenting As a Paraneoplastic Syndrome in Metastatic Melanoma. CJC OPEN, 5(9), 713-716. doi:10.1016/j.cjco.2023.07.003

Bonaventura, A., Moroni, F., Golino, M., Buono, M. G. D. E. L., Vecchie, A., Potere, N., & Abbate, A. (2023). IL-1 blockade in cardiovascular disease: an appraisal of the evidence across different inflammatory paradigms. MINERVA CARDIOLOGY AND ANGIOLOGY. doi:10.23736/S2724-5683.23.06390-1

Golino, M., Moroni, F., Carbone, S., Corna, G., Trankle, C., Billingsley, H. E., . . . Abbate, A. (2023). Differential Response to Interleukin-1 Blockade With Anakinra on Cardiorespiratory Fitness in Patients With Heart Failure With Preserved Ejection Fraction Stratified According to Left Ventricular Ejection Fraction. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 12(18). doi:10.1161/JAHA.123.031251

Naya, N. M., Kelly, J., Corna, G., Golino, M., Abbate, A., & Toldo, S. (2023). Molecular and Cellular Mechanisms of Action of Cannabidiol. MOLECULES, 28(16). doi:10.3390/molecules28165980

Spoto, S., Argemi, J., Di Costanzo, R., Gomez, J. J. G., Gonzales, N. S., Basili, S., . . . Angeletti, S. (2023). Mid-Regional Pro-Adrenomedullin and N-Terminal Pro-B-Type Natriuretic Peptide Measurement: A Multimarker Approach to Diagnosis and Prognosis in Acute Heart Failure. JOURNAL OF PERSONALIZED MEDICINE, 13(7). doi:10.3390/jpm13071155

Moroni, F., & Abbate, A. (2023). Anti-inflammatory (Colchicine) Treatment for Secondary Prevention in Coronary Artery Disease: A Milestone has Been Met. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 82(4), 237-240. doi:10.1097/FJC.0000000000001467

Salmons, H., Ahmed, S. I., Billingsley, H. E., Markley, R., Damonte, J. I., Del Buono, M. G., . . . Carbone, S. (2023). Skeletal muscle quality, measured via phase angle, and cardiorespiratory fitness in patients with obesity and heart failure with preserved ejection fraction. NUTRITION, 116. doi:10.1016/j.nut.2023.112163

Canada, J. M., McCarty, J., Jordan, J. H., Trankle, C. R., DeCamp, K., West, J. D., . . . Hundley, W. G. (2023). Simultaneous exercise stress cardiac magnetic resonance and cardiopulmonary exercise testing to elucidate the Fick components of aerobic exercise capacity: a feasibility and reproducibility study and pilot study in hematologic cancer survivors. CARDIO-ONCOLOGY, 9(1). doi:10.1186/s40959-023-00182-1

Romeo, F. J., Del Buono, M. G., Aguilar-gallardo, J. S., Lorente-ros, M., Damonte, J. I., Chiabrando, J. G., . . . Carbone, S. (2023). Cardiac remodeling with SGLT2 inhibitors in heart failure with reduced ejection fraction. MINERVA CARDIOLOGY AND ANGIOLOGY. doi:10.23736/S2724-5683.22.06207-X

Zito, A., Galli, M., Biondi-Zoccai, G., Abbate, A., Douglas, P. S., Princi, G., . . . Burzotta, F. (2023). Diagnostic Strategies for the Assessment of Suspected Stable Coronary Artery Disease A Systematic Review and Meta-analysis. ANNALS OF INTERNAL MEDICINE, 176(6), 817-+. doi:10.7326/M23-0231

Potere, N., Garrad, E., Kanthi, Y., Di Nisio, M., Kaplanski, G., Bonaventura, A., . . . Abbate, A. (2023). NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis. CARDIOVASCULAR RESEARCH, 119(11), 2046-2060. doi:10.1093/cvr/cvad084

Palazzuoli, A., Del Buono, M. G., Ruocco, G., Caravita, S., Abbate, A., & Lavie, C. J. (2023). The Conundrum of HFpEF Definition: Non-Invasive Assessment Uncertainties and Alternative Diagnostic Strategies (vol 48,101433, 2023). CURRENT PROBLEMS IN CARDIOLOGY, 48(8). doi:10.1016/j.cpcardiol.2023.101758

Ammirati, E., Lupi, L., Palazzini, M., Ciabatti, M., Rossi, V. A., Gentile, P., . . . Pieroni, M. (2023). Outcome and Morphofunctional Changes on Cardiac Magnetic Resonance in Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination. CIRCULATION-HEART FAILURE, 16(6). doi:10.1161/CIRCHEARTFAILURE.122.010315

Golino, M., Moroni, F., Del Buono, M. G., Canada, J. M. M., Talasaz, A. H. H., Pinel, S., . . . Abbate, A. (2023). Change in Eosinophil Count in Patients with Heart Failure Treated with Anakinra. CELLS, 12(8). doi:10.3390/cells12081129

Abbate, G., De Iulio, B., Thomas, G., Priday, A., Biondi-Zoccai, G., Markley, R., & Abbate, A. (2023). Postural Orthostatic Tachycardia Syndrome After COVID-19: A Systematic Review of Therapeutic Interventions. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 82(1), 23-31. doi:10.1097/FJC.0000000000001432

Kron, J., Crawford, T., Bogun, F., Jordan, J. H., Koelling, T., Syed, H., . . . Abbate, A. (2023). Interleukin-1 Blockade in Cardiac Sarcoidosis: A Pilot Study. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 16(5). doi:10.1161/CIRCEP.123.011869

Del Buono, M. G., Damonte, J. I., Moroni, F., Chiabrando, J. G., Markley, R., Turlington, J., . . . Abbate, A. (2023). Clinical and Pharmacological Implications of Time to Treatment with Interleukin-1 Blockade in ST-Segment Elevation Myocardial Infarction. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 386(2), 156-163. doi:10.1124/jpet.123.001601

Moroni, F., Ayers, M. P., Dixon, D. L., & Abbate, A. (2023). Proprotein Convertase Subtilisin Kexin-9 Inhibitors (PCSK9i) in Atherosclerotic Cardiovascular Disease: Real-World Data Welcome. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 81(5), 336-338. doi:10.1097/FJC.0000000000001411

Bonaventura, A., Thomas, G. K., Golino, M., Mauro, A. G., Vecchie, A., Del Buono, M. G., . . . Abbate, A. (2023). Novel Pathophysiological, Diagnostic and Therapeutic Concepts in Acute and Recurrent Pericarditis. REVIEWS IN CARDIOVASCULAR MEDICINE, 24(3). doi:10.31083/j.rcm2403077

Billingsley, H. E., Toldo, S., & Abbate, A. (2023). Fast Today, Feast Tomorrow Can Intermittent Fasting Improve Right Ventricular Function in Pulmonary Arterial Hypertension?. JACC-BASIC TO TRANSLATIONAL SCIENCE, 8(3), 255-257. doi:10.1016/j.jacbts.2023.01.002

Talasaz, A. H., Sculthorpe, R., Pak, M., Lipinski, M., Roberts, C., Markley, R., . . . Abbate, A. (2023). Comparison of Safety and Biological Efficacy of Anakinra (Kineret) Dispensed in Polycarbonate Plastic versus Borosilicate Glass Syringes: A Patient-Level Analysis of VCUART2 and VCUART3 Clinical Trials. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 386(2), 138-142. doi:10.1124/jpet.122.001404

Menachery, S. M., Chuquin, D., Sindel, A., Poklepovic, A., Abbate, A., & Bottinor, W. (2023). Multiple Immunotherapy-Related Cardiovascular Sequelae. CJC OPEN, 5(2), 170-172. doi:10.1016/j.cjco.2022.11.018

Markley, R., Del Buono, M. G., Mihalick, V., Pandelidis, A., Trankle, C., Jordan, J. H., . . . Abbate, A. (2023). Abnormal left ventricular subendocardial perfusion and diastolic function in women with obesity and heart failure and preserved ejection fraction. INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, 39(4), 811-819. doi:10.1007/s10554-022-02782-x

Thomas, G. K., Del Buono, M. G., Damonte, J. I., Moroni, F., Mihalick, V., Billingsley, H. E., . . . Canada, J. M. (2023). Contribution of hemoglobin concentration to cardiorespiratory fitness in black African American patients with recently decompensated heart failure and reduced ejection fraction. MINERVA CARDIOLOGY AND ANGIOLOGY, 71(4), 456-462. doi:10.23736/S2724-5683.22.06226-3

Brucato, A., Wheeler, A., Luis, S. A., Abbate, A., Cremer, P. C., Zou, L., . . . Paolini, J. F. (2023). Transition to rilonacept monotherapy from oral therapies in patients with recurrent pericarditis. HEART, 109(4), 297-304. doi:10.1136/heartjnl-2022-321328

Palazzuoli, A., Buono, M. G. D., Ruocco, G., Caravita, S., Abbate, A., & Lavie, C. J. (2023). The Conundrum of HFpEF Definition: Non-Invasive Assessment Uncertainties and Alternative Diagnostic Strategies. CURRENT PROBLEMS IN CARDIOLOGY, 48(1). doi:10.1016/j.cpcardiol.2022.101433

2022

Moroni, F., Damonte, J. I., Veeramgari, D. P. R., Ravindra, K., Prabhu, S. S., Khan, M., . . . Azzalini, L. (2022). Prognostic Effect of Race on the Risk of Contrast-Associated Acute Kidney Injury Among Patients Who Undergo Percutaneous Coronary Intervention.. The Canadian journal of cardiology, 38(12), 1915-1917. doi:10.1016/j.cjca.2022.09.003

Chuquin, D., Abbate, A., & Bottinor, W. (2022). Hypertension in Cancer Survivors: A Review of the Literature and Suggested Approach to Diagnosis and Treatment. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 80(4), 522-530. doi:10.1097/FJC.0000000000001342

Billingsley, H. E., Del Buono, M. G., Canada, J. M., Kim, Y., Damonte, J. I., Trankle, C. R., . . . Carbone, S. (2022). Sarcopenic Obesity Is Associated With Reduced Cardiorespiratory Fitness Compared With Nonsarcopenic Obesity in Patients With Heart Failure With Reduced Ejection Fraction. CIRCULATION-HEART FAILURE, 15(10). doi:10.1161/CIRCHEARTFAILURE.122.009518

Ammirati, E., Raimondi, F., Piriou, N., Infirri, L. S., Mohiddin, S. A., Mazzanti, A., . . . Cooper, L. T. (2022). Acute Myocarditis Associated With Desmosomal Gene Variants. JACC-HEART FAILURE, 10(10), 714-727. doi:10.1016/j.jchf.2022.06.013

Del Buono, M. G., Moroni, F., Montone, R. A., Azzalini, L., Sanna, T., & Abbate, A. (2022). Ischemic Cardiomyopathy and Heart Failure After Acute Myocardial Infarction. CURRENT CARDIOLOGY REPORTS, 24(10), 1505-1515. doi:10.1007/s11886-022-01766-6

Mauro, A. G., Mezzaroma, E., Toldo, S., Melendez, G. C., Franco, R. L., Lesnefsky, E. J., . . . Salloum, F. N. (2023). NLRP3-mediated inflammation in cardio-oncology: sterile yet harmful. TRANSLATIONAL RESEARCH, 252, 9-20. doi:10.1016/j.trsl.2022.08.004

Moroni, F., Mbualungu, J., & Abbate, A. (2022). Myocarditis after RNA-based COVID-19 vaccines: Where do we stand?. International journal of cardiology, 356, 81-82. doi:10.1016/j.ijcard.2022.03.014

Del Buono, M. G., Garmendia, C. M., Seropian, I. M., Gonzalez, G., Berrocal, D. H., Biondi-Zoccai, G., . . . Abbate, A. (2023). Heart Failure After ST-Elevation Myocardial Infarction: Beyond Left Ventricular Adverse Remodeling. CURRENT PROBLEMS IN CARDIOLOGY, 48(8). doi:10.1016/j.cpcardiol.2022.101215

Vecchie, A., Del Buono, M. G., Mauro, A. G., Cremer, P. C., Imazio, M., Klein, A. L., . . . Bonaventura, A. (2022). Advances in pharmacotherapy for acute and recurrent pericarditis. EXPERT OPINION ON PHARMACOTHERAPY, 23(6), 681-691. doi:10.1080/14656566.2022.2054327

Billingsley, H. E., Canada, J. M., Dixon, D. L., Kirkman, D. L., Bohmke, N., Rotelli, B., . . . Carbone, S. (2022). Midpoint of energy intake, non-fasting time and cardiorespiratory fitness in heart failure with preserved ejection fraction and obesity. INTERNATIONAL JOURNAL OF CARDIOLOGY, 355, 23-27. doi:10.1016/j.ijcard.2022.03.010

Spertus, J. A., Birmingham, M. C., Nassif, M., Damaraju, C. V., Abbate, A., Butler, J., . . . Januzzi, J. L. (2022). The SGLT2 inhibitor canagliflozin in heart failure: the CHIEF-HF remote, patient-centered randomized trial. NATURE MEDICINE, 28(4), 809-+. doi:10.1038/s41591-022-01703-8

Khorasanchi, A., Ansari, A. M., Bottinor, W., Simmons, G., Abbate, A., & Toor, A. A. (2022). Transient left ventricular dysfunction following chimeric antigen receptor T-cell-mediated encephalopathy: A form of stress cardiomyopathy.. EJHaem, 3(1), 231-234. doi:10.1002/jha2.369

Narayan, P., Trikantzopoulos, E., Mezzaroma, E., Mauro, A. G., Vohra, H., Abbate, A., & Toldo, S. (2022). The interleukin-1 receptor type I promotes the development of aging-associated cardiomyopathy in mice. CYTOKINE, 151. doi:10.1016/j.cyto.2022.155811

Canada, J. M., Weiss, E., Grizzard, J. D., Trankle, C. R., Gharai, L. R., Dana, F., . . . Abbate, A. (2022). Influence of extracellular volume fraction on peak exercise oxygen pulse following thoracic radiotherapy. CARDIO-ONCOLOGY, 8(1). doi:10.1186/s40959-021-00127-6

Soares, J. S., Saunders, S. K., Potere, F., Toldo, S., & Abbate, A. (2022). Engineered tissue vascular grafts: Are we there yet?. APPLICATIONS IN ENGINEERING SCIENCE, 12. doi:10.1016/j.apples.2022.100114

Del Buono, M. G., Damonte, J. I., Moroni, F., Ravindra, K., Westman, P., Chiabrando, J. G., . . . Abbate, A. (2022). QT Prolongation and In-Hospital Ventricular Arrhythmic Complications in Patients With Apical Ballooning Takotsubo Syndrome. JACC-CLINICAL ELECTROPHYSIOLOGY, 8(12), 1500-1510. doi:10.1016/j.jacep.2022.08.010

Spoto, S., Mangiacapra, F., D'Avanzo, G., Lemme, D., Guillen, C. B., Abbate, A., . . . Angeletti, S. (2022). Synergistic effect of myocardial injury and mid-regional proAdrenomedullin elevation in determining clinical outcomes of SARS-CoV-2 patients. FRONTIERS IN MEDICINE, 9. doi:10.3389/fmed.2022.929408

Potere, N., Del Buono, M. G., Caricchio, R., Cremer, P. C., Vecchie, A., Porreca, E., . . . Bonaventura, A. (2022). Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications. EBIOMEDICINE, 85. doi:10.1016/j.ebiom.2022.104299

Del Buono, M. G., Trankle, C. R., Buckley, L., Kadariya, D., Canada, J. M., Carbone, S., . . . Abbate, A. (2022). Early changes in N-terminal pro-brain natriuretic peptide levels predict new-onset heart failure in patients with STEMI. MINERVA CARDIOLOGY AND ANGIOLOGY, 70(1), 25-31. doi:10.23736/S2724-5683.20.05303-7

Potere, N., Di Nisio, M., Cibelli, D., Scurti, R., Frattari, A., Porreca, E., . . . Parruti, G. (2022). Response to: 'Rational use of tocilizumab in COVID-19' by Jain and Sharma. ANNALS OF THE RHEUMATIC DISEASES, 81(11). doi:10.1136/annrheumdis-2020-218626

Moeller, W. J., Potere, N., Bonaventura, A., Vecchie, A., Sedhai, Y. R., Caricchio, R., & Abbate, A. (2022). Use of placebo in clinical trials in COVID-19 pandemic times: considerations on pros, cons, challenges and limitations. MINERVA MEDICA, 113(6), 1000-1007. doi:10.23736/S0026-4806.21.07566-2

Montone, R. A., La Vecchia, G., Buono, M. G. D., Abbate, A., Sanna, T., Pedicino, D., . . . Crea, F. (2022). Takotsubo Syndrome in Intensive Cardiac Care Unit: Challenges in Diagnosis and Management. CURRENT PROBLEMS IN CARDIOLOGY, 47(11). doi:10.1016/j.cpcardiol.2021.101084

Mihalick, V., Wohlford, G., Talasaz, A. H., Ho, A. -C. J., Kim, F., Canada, J. M., . . . Van Tassell, B. (2022). Patient Perceptions of Exertion and Dyspnea With Interleukin-1 Blockade in Patients With Recently Decompensated Systolic Heart Failure. AMERICAN JOURNAL OF CARDIOLOGY, 174, 61-67. doi:10.1016/j.amjcard.2022.03.026

Dixon, D. L., Patel, J., Spence, R., Talasaz, A. H., Abbate, A., & Wiggins, B. S. (2022). Select drug-drug interactions with colchicine and cardiovascular medications: A review. AMERICAN HEART JOURNAL, 252, 42-50. doi:10.1016/j.ahj.2022.06.002

Van Tassell, B. W., Wohlford, G. F., Del Buono, M. G., Damonte, J. I., Markley, R., Turlington, J., . . . Abbate, A. (2022). Safety, Tolerability, and Effects of a Single Subcutaneous Administration of SP16-a SERPIN-like, Small Peptide Agonist of the Low-Density Lipoprotein-like Receptor 1-on the Acute Inflammatory Response in Patients With ST-Segment Elevation Myocardial Infarction. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 80(5), 672-678. doi:10.1097/FJC.0000000000001331

Burashnikov, A., Abbate, A., & Booz, G. W. (2022). Cardiovascular Complications of Anticancer Therapy: A Developing Storm in Medicine. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 80(4), 491-492. doi:10.1097/FJC.0000000000001355

Blanks, A. M., Pedersen, L. N., Caslin, H. L., Mihalick, V. L., Via, J., Canada, J. M., . . . Franco, R. L. (2022). LPS differentially affects expression of CD14 and CCR2 in monocyte subsets of Post-STEMI patients with hyperglycemia. DIABETES RESEARCH AND CLINICAL PRACTICE, 191. doi:10.1016/j.diabres.2022.110077

Imazio, M., Lazaros, G., Gattorno, M., LeWinter, M., Abbate, A., Brucato, A., & Klein, A. (2022). Anti-interleukin-1 agents for pericarditis: a primer for cardiologists. EUROPEAN HEART JOURNAL, 43(31), 2946-2957. doi:10.1093/eurheartj/ehab452

Potere, N., del Buono, M. G., Vecchie, A., Porreca, E., Abbate, A., Dentali, F., & Bonaventura, A. (2022). Diabetes mellitus and heart failure: an update on pathophysiology and therapy. MINERVA CARDIOLOGY AND ANGIOLOGY, 70(3), 344-356. doi:10.23736/S2724-5683.22.05967-1

Bonaventura, A., Vecchie, A., Dagna, L., Tangianu, F., Abbate, A., & Dentali, F. (2022). Colchicine for COVID-19: targeting NLRP3 inflammasome to blunt hyperinflammation. INFLAMMATION RESEARCH, 71(3), 293-307. doi:10.1007/s00011-022-01540-y

Becatti, M., Abbate, A., Fiorillo, C., Carnevale, R., & Kumar, S. (2022). Editorial: New Insights Into Oxidative Stress and Inflammation in the Pathophysiology and Treatment of Cardiovascular Diseases. FRONTIERS IN MOLECULAR BIOSCIENCES, 9. doi:10.3389/fmolb.2022.940465

Potere, N., Di Nisio, M., Cibelli, D., Scurti, R., Frattari, A., Porreca, E., . . . Parruti, G. (2022). Response to: 'Correspondence on 'Interleukin-6 blockade with subcutaneous tocilizumab in severe COVID-19 pneumonia and hyperinflammation: a case-control study' by Potere et al' by Buckley. ANNALS OF THE RHEUMATIC DISEASES, 81(10). doi:10.1136/annrheumdis-2020-218715

Imazio, M., & Abbate, A. (2022). The inflammasome as a therapeutic target for myopericardial diseases. MINERVA CARDIOLOGY AND ANGIOLOGY, 70(2), 238-247. doi:10.23736/S2724-5683.21.05876-2

Spoto, S., Markley, J. D., Valeriani, E., Abbate, A., Argemi, J., Markley, R., . . . Angeletti, S. (2022). Active Surveillance Cultures and Procalcitonin in Combination With Clinical Data to Guide Empirical Antimicrobial Therapy in Hospitalized Medical Patients With Sepsis. FRONTIERS IN MICROBIOLOGY, 13. doi:10.3389/fmicb.2022.797932

Del Buono, M. G., Damonte, J. I., Trankle, C. R., Kadariya, D., Carbone, S., Thomas, G., . . . Abbate, A. (2022). Effect of interleukin-1 blockade with anakinra on leukocyte count in patients with ST-segment elevation acute myocardial infarction. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-05374-w

Abbate, A., Wohlford, G. F., Del Buono, M. G., Chiabrando, J. G., Markley, R., Turlington, J., . . . Van Tassell, B. W. (2022). Interleukin-1 blockade with anakinra and heart failure following ST-segment elevation myocardial infarction: results from a pooled analysis of the VCUART clinical trials. EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY, 8(5), 503-510. doi:10.1093/ehjcvp/pvab075

Moroni, F., & Abbate, A. (2022). Late breaking clinical trials at ACC 22. EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY, 8(5), E26. doi:10.1093/ehjcvp/pvac031

Canada, J. M., Park, T. S., Ravindra, K., Chiabrando, J. G., Del Buono, M. G., van Wezenbeek, J., . . . Abbate, A. (2022). Comparison of Cardiorespiratory Fitness in Black or African American Versus Caucasian Patients With Heart Failure. JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION, 42(1), 39-44. doi:10.1097/HCR.0000000000000605

Del Buono, M. G., Damonte, J. I., Chiabrando, J. G., Markley, R., Turlington, J., Trankle, C. R., . . . Abbate, A. (2022). Effect of IL-1 Blockade With Anakinra on Heart Failure Outcomes in Patients With Anterior Versus Nonanterior ST Elevation Myocardial Infarction. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 79(6), 774-780. doi:10.1097/FJC.0000000000001240

Damonte, J. I., Del Buono, M. G., Thomas, G. K., Mbualungu, J., Clark, B., Montone, R. A., . . . Kron, J. (2022). Arrhythmic Recurrence and Outcomes in Patients Hospitalized With First Episode of Electrical Storm. AMERICAN JOURNAL OF CARDIOLOGY, 172, 40-47. doi:10.1016/j.amjcard.2022.02.032

Zaman, A., Zhao, S., Kron, J., Abbate, A., Tomdio, A., Hundley, W. G., & Jordan, J. H. (2022). Role of Cardiac MRI Imaging of Focal and Diffuse Inflammation and Fibrosis in Cardiomyopathy Patients Who Have Pacemakers/ICD Devices. CURRENT CARDIOLOGY REPORTS, 24(11), 1529-1536. doi:10.1007/s11886-022-01770-w

Van Tassell, B., Mihalick, V., Thomas, G., Marawan, A., Talasaz, A. H., Lu, J., . . . Abbate, A. (2022). Rationale and design of interleukin-1 blockade in recently decompensated heart failure (REDHART2): a randomized, double blind, placebo controlled, single center, phase 2 study. JOURNAL OF TRANSLATIONAL MEDICINE, 20(1). doi:10.1186/s12967-022-03466-9

Billingsley, H., Dixon, D., Yehya, A., Carbone, S., & Abbate, A. (2022). Sleeve Gastrectomy Reduces BMI and Pill Count in Patients With LVAD. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 79(5), 644-645. doi:10.1097/FJC.0000000000001249

Chen, S., Wohlford, G. F., Vecchie, A., Carbone, S., Yavuz, S., Van Tassell, B., . . . Celi, F. S. (2022). Acute Effects of Liothyronine Administration on Cardiovascular System and Energy Metabolism in Healthy Volunteers. FRONTIERS IN ENDOCRINOLOGY, 13. doi:10.3389/fendo.2022.843539

Sedhai, Y. R., Patel, N. K., Mihalick, V., Talasaz, A., Thomas, G., Denlinger, B. L., . . . Abbate, A. (2022). Heart failure clinical trial enrollment at a rural satellite hospital. CONTEMPORARY CLINICAL TRIALS, 115. doi:10.1016/j.cct.2022.106731

Cannata, A., Merlo, M., Dal Ferro, M., Barbati, G., Manca, P., Paldino, A., . . . Sinagra, G. (2022). Association of Titin Variations With Late-Onset Dilated Cardiomyopathy. JAMA CARDIOLOGY, 7(4), 371-377. doi:10.1001/jamacardio.2021.5890

2021

Toldo, S., Mezzaroma, E., Buckley, L. F., Potere, N., Di Nisio, M., Biondi-Zoccai, G., . . . Abbate, A. (2022). Targeting the NLRP3 inflammasome in cardiovascular diseases. PHARMACOLOGY & THERAPEUTICS, 236. doi:10.1016/j.pharmthera.2021.108053

Vecchie, A., Thomas, G., Bressi, E., Bonaventura, A., Canada, J. M., Chuquin, D., . . . Abbate, A. (2021). Orthostatic intolerance syndromes after hematopoietic cell transplantation: clinical characteristics and therapeutic interventions in a single-center experience. CARDIO-ONCOLOGY, 7(1). doi:10.1186/s40959-021-00126-7

Kron, J., Crawford, T., Mihalick, V., Bogun, F., Jordan, J. H., Koelling, T., . . . Abbate, A. (2021). Interleukin-1 blockade in cardiac sarcoidosis: study design of the multimodality assessment of granulomas in cardiac sarcoidosis: Anakinra Randomized Trial (MAGiC-ART). JOURNAL OF TRANSLATIONAL MEDICINE, 19(1). doi:10.1186/s12967-021-03130-8

Patel, J., Pallazola, V. A., Dudum, R., Greenland, P., McEvoy, J., Blumenthal, R. S., . . . Al Rifai, M. (2021). Assessment of Coronary Artery Calcium Scoring to Guide Statin Therapy Allocation According to Risk-Enhancing Factors The Multi-Ethnic Study of Atherosclerosis. JAMA CARDIOLOGY, 6(10), 1161-1170. doi:10.1001/jamacardio.2021.2321

Cavender, M. A., O'Donoghue, M. L., Abbate, A., Aylward, P., Fox, K. A., Glaser, R. X., . . . Morrow, D. A. (2022). Inhibition of p38 MAP kinase in patients with ST-elevation myocardial infarction - findings from the LATITUDE-TIMI 60 trial. AMERICAN HEART JOURNAL, 243, 147-157. doi:10.1016/j.ahj.2021.08.022

Vecchié, A., Raybould, J. E., Sangal, K., Bonaventura, A., Gillen, M., Abbate, A., . . . Bhardwaj, H. (2021). Pericarditis and Sacroiliitis in a World Traveler.. JACC. Case reports, 3(10), 1322-1326. doi:10.1016/j.jaccas.2021.04.019

Caricchio, R., Abbate, A., Gordeev, I., Meng, J., Hsue, P. Y., Neogi, T., . . . Noviello, S. (2021). Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19 A Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(3), 230-239. doi:10.1001/jama.2021.9508

Iannaccone, G., Abbate, A., Keen, L. I. I., & Porto, I. (2021). Cannabis medical and recreational use: science beyond ethical and political issues. MINERVA CARDIOLOGY AND ANGIOLOGY, 69(4), 475-476. doi:10.23736/S2724-5683.21.05664-7

Billingsley, H. E., Dixon, D. L., Canada, J. M., Kirkman, D. L., Rotelli, B., Kadariya, D., . . . Carbone, S. (2021). Time of eating and cardiorespiratory fitness in patients with heart failure with preserved ejection fraction and obesity. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 31(8), 2471-2473. doi:10.1016/j.numecd.2021.04.018

Rabender, C. S., Mezzaroma, E., Yakovlev, V. A., Mauro, A. G., Bonaventura, A., Abbate, A., & Mikkelsen, R. B. (2021). Mitigation of Radiation-Induced Lung and Heart Injuries in Mice by Oral Sepiapterin after Irradiation. RADIATION RESEARCH, 195(5), 463-473. doi:10.1667/RADE-20-00249.1

Lombardi, M., Carbone, S., Del Buono, M. G., Chiabrando, J. G., Vescovo, G. M., Camilli, M., . . . Crea, F. (2021). Omega-3 fatty acids supplementation and risk of atrial fibrillation: an updated meta-analysis of randomized controlled trials. EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY, 7(4), E69-E70. doi:10.1093/ehjcvp/pvab008

Lin, D., Klein, A., Cella, D., Beutler, A., Fang, F., Magestro, M., . . . Paolini, J. F. (2021). Health-related quality of life in patients with recurrent pericarditis: results from a phase 2 study of rilonacept. BMC CARDIOVASCULAR DISORDERS, 21(1). doi:10.1186/s12872-021-02008-3

Bonaventura, A., Vecchie, A., Dagna, L., Martinod, K., Dixon, D. L., Van Tassell, B. W., . . . Abbate, A. (2021). Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19. NATURE REVIEWS IMMUNOLOGY, 21(5), 319-329. doi:10.1038/s41577-021-00536-9

Gaudino, M., Di Franco, A., Bhatt, D. L., Alexander, J. H., Abbate, A., Azzalini, L., . . . Bangalore, S. (2021). The association between coronary graft patency and clinical status in patients with coronary artery disease. EUROPEAN HEART JOURNAL, 42(14), 1433-+. doi:10.1093/eurheartj/ehab096

Cremer, P. C., Abbate, A., Hudock, K., McWilliams, C., Mehta, J., Chang, S. Y., . . . Trapnell, B. C. (2021). Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind, randomised, placebo-controlled trial. LANCET RHEUMATOLOGY, 3(6), E410-E418. doi:10.1016/S2665-9913(21)00070-9

Klein, A. L., Lin, D., Cremer, P. C., Nasir, S., Luis, S. A., Abbate, A., . . . Paolini, J. F. (2021). Efficacy and safety of rilonacept for recurrent pericarditis: results from a phase II clinical trial. HEART, 107(6), 488-496. doi:10.1136/heartjnl-2020-317928

Chiabrando, J. G., Vescovo, G. M., Lombardi, M., Del Buono, M. G., Romeo, F. J., Berrocal, D. H., . . . Abbate, A. (2021). Long-term outcomes of percutaneous or surgical treatment in left main disease. MINERVA CARDIOLOGY AND ANGIOLOGY, 69(3), 313-321. doi:10.23736/S2724-5683.20.05370-0

Imazio, M., Lazaros, G., Gattorno, M., Abbate, A., & Brucato, A. (2021). Interleukin-1 antagonists: a new class of drugs for the treatment of recurrent pericarditis. A practical guide for the clinical cardiologist. GIORNALE ITALIANO DI CARDIOLOGIA, 22(10), 833-843.

Potere, N., Batticciotto, A., Vecchie, A., Porreca, E., Cappelli, A., Abbate, A., . . . Bonaventura, A. (2021). The role of IL-6 and IL-6 blockade in COVID-19. EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 17(6), 601-617. doi:10.1080/1744666X.2021.1919086

Potere, N., Di Nisio, M., Cibelli, D., Scurti, R., Frattari, A., Porreca, E., . . . Parruti, G. (2021). Interleukin-6 receptor blockade with subcutaneous tocilizumab in severe COVID-19 pneumonia and hyperinflammation: a case-control study. ANNALS OF THE RHEUMATIC DISEASES, 80(2), 271-+. doi:10.1136/annrheumdis-2020-218243

Vecchie, A., Del Buono, M. G., Chiabrando, G. J., Dentali, F., Abbate, A., & Bonaventura, A. (2021). Interleukin-1 and the NLRP3 Inflammasome in Pericardial Disease. CURRENT CARDIOLOGY REPORTS, 23(11). doi:10.1007/s11886-021-01589-x

Chiabrando, J. G., Lombardi, M., Vescovo, G. M., Wohlford, G. F., Koenig, R. A., Abbate, A., . . . Biondi-Zoccai, G. (2021). Stenting techniques for coronary bifurcation lesions: Evidence from a network meta-analysis of randomized clinical trials. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 97(3), E306-E318. doi:10.1002/ccd.29097

Bonaventura, A., Vecchie, A., Mauro, A. G., Brucato, A. L., Imazio, M., & Abbate, A. (2021). An update on the pathophysiology of acute and recurrent pericarditis. PANMINERVA MEDICA, 63(3), 249-260. doi:10.23736/S0031-0808.20.04205-6

Del Buono, M. G., Mihalick, V., Damonte, J. I., Billingsley, H., Vecchie, A., Trankle, C. R., . . . Canada, J. M. (2021). Preservation of Cardiac Reserve and Cardiorespiratory Fitness in Patients With Acute De Novo Versus Acute on Chronic Heart Failure With Reduced Ejection Fraction. AMERICAN JOURNAL OF CARDIOLOGY, 158, 74-80. doi:10.1016/j.amjcard.2021.07.036

Mauro, A. G., Bonaventura, A., Vecchie, A., Mezzaroma, E., Carbone, S., Narayan, P., . . . Toldo, S. (2021). The Role of NLRP3 Inflammasome in Pericarditis. JACC-BASIC TO TRANSLATIONAL SCIENCE, 6(2), 137-150. doi:10.1016/j.jacbts.2020.11.016

Mihalick, V. L., Canada, J. M., Arena, R., Abbate, A., & Kirkman, D. L. (2021). Cardiopulmonary exercise testing during the COVID-19 pandemic. PROGRESS IN CARDIOVASCULAR DISEASES, 67, 35-39. doi:10.1016/j.pcad.2021.04.005

Del Buono, M. G., Vecchie, A., Damonte, J. I., Chiabrando, J. G., Dell, M. S., Bonaventura, A., . . . Abbate, A. (2021). Pericarditis Recurrence After Initial Uncomplicated Clinical Course. AMERICAN JOURNAL OF CARDIOLOGY, 160, 112-116. doi:10.1016/j.amjcard.2021.08.048

Samsonov, M., Bogin, V., Van Tassell, B. W., & Abbate, A. (2021). Interleukin-1 blockade with RPH-104 in patients with acute ST-elevation myocardial infarction: study design and rationale. JOURNAL OF TRANSLATIONAL MEDICINE, 19(1). doi:10.1186/s12967-021-02828-z

Del Buono, M. G., Damonte, J. I., Trankle, C. R., Bhardwaj, H., Markley, R., Turlington, J., . . . Abbate, A. (2021). Sacubitril/Valsartan for the Prevention and Treatment of Postinfarction Heart Failure: Ready to Use?. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 78(3), 331-333. doi:10.1097/FJC.0000000000001103

Del Buono, M. G., Van Tassell, B. W., & Abbate, A. (2021). Clarification Regarding the Lack of Heart Failure Events in the ASSAIL-MI Trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 78(6), 637. doi:10.1016/j.jacc.2021.04.105

Wohlford, G. F., Buckley, L. F., Kadariya, D., Park, T., Chiabrando, J. G., Carbone, S., . . . Van Tassell, B. (2021). A phase 1 clinical trial of SP16, a first-in-class anti-inflammatory LRP1 agonist, in healthy volunteers. PLOS ONE, 16(5). doi:10.1371/journal.pone.0247357

Heizer, J., Carbone, S., Billingsley, H. E., Van Tassell, B. W., Arena, R., Abbate, A., & Canada, J. M. (2021). Left ventricular concentric remodeling and impaired cardiorespiratory fitness in patients with heart failure and preserved ejection fraction. MINERVA CARDIOLOGY AND ANGIOLOGY, 69(4), 438-445. doi:10.23736/S2724-5683.20.05295-0

Toldo, S., Bussani, R., Nuzzi, V., Bonaventura, A., Mauro, A. G., Cannata, A., . . . Abbate, A. (2021). Inflammasome formation in the lungs of patients with fatal COVID-19. INFLAMMATION RESEARCH, 70(1), 7-10. doi:10.1007/s00011-020-01413-2

Dixon, D. L., Billingsley, H. E., Canada, J. M., Trankle, C. R., Kadariya, D., Cooke, R., . . . Carbone, S. (2021). Effect of Canagliflozin Compared With Sitagliptin on Serum Lipids in Patients with Type 2 Diabetes Mellitus and Heart Failure with Reduced Ejection Fraction: A Post-Hoc Analysis of the CANA-HF Study. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 78(3), 407-410. doi:10.1097/FJC.0000000000001083

Vecchie, A., Dell, M., Mbualungu, J., Ho, A. -C., Van Tassell, B., & Abbate, A. (2021). Recurrent pericarditis: an update on diagnosis and management. PANMINERVA MEDICA, 63(3), 261-269. doi:10.23736/S0031-0808.21.04210-5

Marawan, A., Thomas, G. K., Canada, J. M., Billingsley, H. E., Dixon, D. L., Van Tassell, B. W., . . . Carbone, S. (2021). Edema Index Predicts Cardiorespiratory Fitness in Patients With Heart Failure With Reduced Ejection Fraction and Type 2 Diabetes Mellitus. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8). doi:10.1161/JAHA.120.018631

Keen, L., Abbate, A., Clark, V., Moeller, F. G., & Tan, A. Y. (2021). Differences in heart rate among recent marijuana use groups. MINERVA CARDIOLOGY AND ANGIOLOGY, 69(4), 469-473. doi:10.23736/S2724-5683.20.05239-1

Mezzaroma, E., Abbate, A., & Toldo, S. (2021). NLRP3 Inflammasome Inhibitors in Cardiovascular Diseases. MOLECULES, 26(4). doi:10.3390/molecules26040976

Aliaga, J., Bonaventura, A., Mezzaroma, E., Dhakal, Y., Mauro, A. G., Abbate, A., & Toldo, S. (2021). Preservation of Contractile Reserve and Diastolic Function by Inhibiting the NLRP3 Inflammasome with OLT1177(R) (Dapansutrile) in a Mouse Model of Severe Ischemic Cardiomyopathy Due to Non-Reperfused Anterior Wall Myocardial Infarction. MOLECULES, 26(12). doi:10.3390/molecules26123534

Johns, S. E., Keyser-Marcus, L., Abbate, A., Boone, E., Van Tassell, B., Cunningham, K. A., . . . Moeller, F. G. (2021). Safety and Preliminary Efficacy of Lorcaserin for Cocaine Use Disorder: A Phase I Randomized Clinical Trial. FRONTIERS IN PSYCHIATRY, 12. doi:10.3389/fpsyt.2021.666945

Kirkman, D. L., Bohmke, N., Carbone, S., Garten, R. S., Rodriguez-Miguelez, P., Franco, R. L., . . . Abbate, A. (2021). Exercise intolerance in kidney diseases: physiological contributors and therapeutic strategies. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 320(2), F161-F173. doi:10.1152/ajprenal.00437.2020

Bobb, L., Ballance, L. R., Abbate, A., Bain, J. C., Sime, P. J., Moeller, F. G., . . . DiazGranados, D. (2021). Center for clinical and translational research COVID-19 clinical trial committee: The development of a review and prioritization matrix during a pandemic. JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE, 5(1). doi:10.1017/cts.2021.4

Thomas, G. K., Trankle, C. R., Carbone, S., Billingsley, H., Van Tassell, B. W., Evans, R. K., . . . Canada, J. M. (2021). Diastolic Dysfunction Contributes to Impaired Cardiorespiratory Fitness in Patients with Lung Cancer and Reduced Lung Function Following Chest Radiation. LUNG, 199(4), 403-407. doi:10.1007/s00408-021-00454-6

Kirkman, D. L., Carbone, S., Canada, J. M., Trankle, C., Kadariya, D., Buckley, L., . . . Abbate, A. (2021). The Chronic Kidney Disease Phenotype of HFpEF: Unique Cardiac Characteristics. AMERICAN JOURNAL OF CARDIOLOGY, 142, 143-145. doi:10.1016/j.amjcard.2020.12.012

Abbate, A., Gavin, J., Madanchi, N., Kim, C., Shah, P. R., Klein, K., . . . Danielides, S. (2021). Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients. INTERNATIONAL JOURNAL OF CARDIOLOGY, 340, 119-121. doi:10.1016/j.ijcard.2021.08.018

Spertus, J. A., Birmingham, M. C., Butler, J., Lingvay, I., Lanfear, D. E., Abbate, A., . . . Whang, J. (2021). Novel Trial Design: CHIEF-HF. CIRCULATION-HEART FAILURE, 14(3), 396-404. doi:10.1161/CIRCHEARTFAILURE.120.007767

Sedhai, Y. R., Sears, M., Vecchie, A., Bonaventura, A., Greer, J., Spence, K., . . . Abbate, A. (2021). Clinical trial enrollment at a rural satellite hospital during COVID-19 pandemic. JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE, 5(1). doi:10.1017/cts.2021.777

Canada, J. M., Reynolds, M. A., Myers, R., West, J., Sweat, K., Powell, C., . . . Hundley, W. G. (2021). Usefulness of the Duke Activity Status Index to Select an Optimal Cardiovascular Exercise Stress Test Protocol. AMERICAN JOURNAL OF CARDIOLOGY, 146, 107-114. doi:10.1016/j.amjcard.2021.01.030

Ravindra, K., del Buono, M. G., Chiabrando, J. G., Westman, P., Bressi, E., Kadariya, D., . . . Abbate, A. (2021). Clinical features and outcomes between African American and Caucasian patients with Takotsubo Syndrome. MINERVA CARDIOLOGY AND ANGIOLOGY, 69(6), 750-759. doi:10.23736/S2724-5683.20.05456-0

2020

Klein, A. L., Imazio, M., Cremer, P., Brucato, A., Abbate, A., Fang, F., . . . Paolini, J. F. (2021). Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis. NEW ENGLAND JOURNAL OF MEDICINE, 384(1), 31-41. doi:10.1056/NEJMoa2027892

Sternberg, M. E., Gertz, Z. M., Quader, M. A., Abbate, A., & Trankle, C. R. (2020). Ventriculoseptal Rupture Caused by Takotsubo Syndrome.. JACC. Case reports, 2(13), 2072-2077. doi:10.1016/j.jaccas.2020.09.018

Wohlford, G. F., Van Tassell, B. W., Billingsley, H. E., Kadariya, D., Canada, J. M., Carbone, S., . . . Abbate, A. (2021). Phase 1B, Randomized, Double-Blinded, Dose Escalation, Single-Center, Repeat Dose Safety and Pharmacodynamics Study of the Oral NLRP3 Inhibitor Dapansutrile in Subjects With NYHA II-III Systolic Heart Failure. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 77(1), 49-60. doi:10.1097/FJC.0000000000000931

Mezzaroma, E., Abbate, A., & Toldo, S. (2021). The inflammasome in heart failure. CURRENT OPINION IN PHYSIOLOGY, 19, 105-112. doi:10.1016/j.cophys.2020.09.013

Ma, L., Hettema, J. M., Cousijn, J., Bjork, J. M., Steinberg, J. L., Keyser-Marcus, L., . . . Moeller, F. G. (2021). Resting-State Directional Connectivity and Anxiety and Depression Symptoms in Adult Cannabis Users. BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING, 6(5), 545-555. doi:10.1016/j.bpsc.2020.09.015

Vecchie, A., Bonaventura, A., Toldo, S., Dagna, L., Dinarello, C. A., & Abbate, A. (2021). IL-18 and infections: Is there a role for targeted therapies?. JOURNAL OF CELLULAR PHYSIOLOGY, 236(3), 1638-1657. doi:10.1002/jcp.30008

Buckley, L. F., Wohlford, G. F., Ting, C., Alahmed, A., Van Tassell, B. W., Abbate, A., . . . Libby, P. (2020). Role for Anti-Cytokine Therapies in Severe Coronavirus Disease 2019.. Critical care explorations, 2(8), e0178. doi:10.1097/cce.0000000000000178

Potere, N., Valeriani, E., Candeloro, M., Tana, M., Porreca, E., Abbate, A., . . . Di Nisio, M. (2020). Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis. CRITICAL CARE, 24(1). doi:10.1186/s13054-020-03022-1

Dixon, D. L., Van Tassell, B. W., Vecchie, A., Bonaventura, A., Talasaz, A. H., Kakavand, H., . . . Abbate, A. (2020). Cardiovascular Considerations in Treating Patients With Coronavirus Disease 2019 (COVID-19). JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 75(5), 359-367. doi:10.1097/FJC.0000000000000836

Abbate, A., Toldo, S., Marchetti, C., Kron, J., Van Tassell, B. W., & Dinarello, C. A. (2020). Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease. CIRCULATION RESEARCH, 126(9), 1260-1280. doi:10.1161/CIRCRESAHA.120.315937

Kadariya, D., Canada, J. M., Del Buono, M. G., van Wezenbeek, J., Tchoukina, I., Arena, R., . . . Abbate, A. (2020). Peak Oxygen Uptake Recovery Delay After Maximal Exercise in Patients With Heart Failure. JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION, 40(6), 434-437. doi:10.1097/HCR.0000000000000502

Abbate, A., Trankle, C. R., Buckley, L. F., Lipinski, M. J., Appleton, D., Kadariya, D., . . . Van Tassell, B. W. (2020). Interleukin-1 Blockade Inhibits the Acute Inflammatory Response in Patients With ST-Segment-Elevation Myocardial Infarction. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 9(5). doi:10.1161/JAHA.119.014941

Bonaventura, A., Vecchie, A., Abbate, A., & Montecucco, F. (2020). Neutrophil Extracellular Traps and Cardiovascular Diseases: An Update. CELLS, 9(1). doi:10.3390/cells9010231

Chiabrando, J. G., Bonaventura, A., Vecchie, A., Wohlford, G. F., Mauro, A. G., Jordan, J. H., . . . Abbate, A. (2020). Management of Acute and Recurrent Pericarditis JACC State-of-the-Art Review. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 75(1), 76-92. doi:10.1016/j.jacc.2019.11.021

Tambone, V., Boudreau, D., Ciccozzi, M., Sanders, K., Campanozzi, L. L., Wathuta, J., . . . Mercurio, M. (2020). Ethical Criteria for the Admission and Management of Patients in the ICU Under Conditions of Limited Medical Resources: A Shared International Proposal in View of the COVID-19 Pandemic. FRONTIERS IN PUBLIC HEALTH, 8. doi:10.3389/fpubh.2020.00284

Zoccai, G. B., Carnevale, R., Vitali, M., Tritapepe, L., Martinelli, O., Macrina, F., . . . Frati, G. (2020). A randomized trial comparing the acute coronary, systemic, and environmental effects of electronic vaping cigarettes versus heat-not-bum cigarettes in smokers of combustible cigarettes undergoing invasive coronary assessment: rationale and design of the SUR-VAPES 3 trial. MINERVA CARDIOANGIOLOGICA, 68(6), 548-555. doi:10.23736/S0026-4725.20.05181-6

Biondi-Zoccai, G., Garmenda, C. M., Abbate, A., Giordano, A., Frati, G., Sciarretta, S., . . . Versaci, F. (2020). Atherothrombosis Prevention and Treatment with Anti-interleukin-1 Agents. CURRENT ATHEROSCLEROSIS REPORTS, 22(1). doi:10.1007/s11883-020-0819-1

Mangiacapra, F., Del Buono, M. G., Abbate, A., Gori, T., Barbato, E., Montone, R. A., . . . Niccoli, G. (2020). Role of endothelial dysfunction in determining angina after percutaneous coronary intervention: Learning from pathophysiology to optimize treatment. PROGRESS IN CARDIOVASCULAR DISEASES, 63(3), 233-242. doi:10.1016/j.pcad.2020.02.009

Iannaccone, G., Scacciavillani, R., Del Buono, M. G., Camilli, M., Ronco, C., Lavie, C. J., . . . Aspromonte, N. (2020). Weathering the Cytokine Storm in COVID-19: Therapeutic Implications. CARDIORENAL MEDICINE, 10(5), 277-287. doi:10.1159/000509483

Ucciferri, C., Auricchio, A., Di Nicola, M., Potere, N., Abbate, A., Cipollone, F., . . . Falasca, K. (2020). Canakinumab in a subgroup of patients with COVID-19. LANCET RHEUMATOLOGY, 2(8), E457-E458. doi:10.1016/S2665-9913(20)30167-3

Klein, A. L., Imazio, M., Brucato, A., Cremer, P., LeWinter, M., Abbate, A., . . . Paolini, J. F. (2020). RHAPSODY: Rationale for and design of a pivotal Phase 3 trial to assess efficacy and safety of rilonacept, an interleukin-1α and interleukin-1β trap, in patients with recurrent pericarditis. AMERICAN HEART JOURNAL, 228, 81-90. doi:10.1016/j.ahj.2020.07.004

Potere, N., Di Nisio, M., Rizzo, G., La Vella, M., Polilli, E., Agostinone, A., . . . Parruti, G. (2020). Low-dose subcutaneous tocilizumab to prevent disease progression in patients with moderate COVID-19 pneumonia and hyperin fl ammation. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 100, 421-424. doi:10.1016/j.ijid.2020.07.078

Biondi-Zoccai, G., Garmendia, C. M., Abbate, A., Giordano, A., Frati, G., Sciarretta, S., . . . Versaci, F. (2020). Atherothrombosis Prevention and Treatment with Anti-interleukin-1 Agents (vol 22, pg 4, 2020). CURRENT ATHEROSCLEROSIS REPORTS, 22(1). doi:10.1007/s11883-020-0827-1

Nahrendorf, M., Abbate, A., & Narula, J. (2020). Deciphering post-infarct inflammation: Should it heal, would it hurt?. JOURNAL OF NUCLEAR CARDIOLOGY, 27(6), 2100-2102. doi:10.1007/s12350-020-02053-z

Nahrendorf, M., Abbate, A., & Narula, J. (2020). Deciphering post-infarct inflammation: Should it heal, would it hurt? (vol 52, pg 631, 2020). JOURNAL OF NUCLEAR CARDIOLOGY, 27(4), 1384. doi:10.1007/s12350-020-02090-8

Del Buono, M. G., Iannaccone, G., Scacciavillani, R., Carbone, S., Camilli, M., Niccoli, G., . . . Abbate, A. (2020). Heart failure with preserved ejection fraction diagnosis and treatment: An updated review of the evidence. PROGRESS IN CARDIOVASCULAR DISEASES, 63(5), 570-584. doi:10.1016/j.pcad.2020.04.011

Boukhris, M., Hillani, A., Moroni, F., Annabi, M. S., Addad, F., Ribeiro, M. H., . . . Azzalini, L. (2020). Cardiovascular Implications of the COVID-19 Pandemic: A Global Perspective. CANADIAN JOURNAL OF CARDIOLOGY, 36(7), 1068-1080. doi:10.1016/j.cjca.2020.05.018

Gomez-Arroyo, J., Voelkel, N. F., & Abbate, A. (2020). SCUBE Diving Biomarker Discovery for Pulmonary Hypertension From Bench to Bedside. JACC-BASIC TO TRANSLATIONAL SCIENCE, 5(11), 1093-1094. doi:10.1016/j.jacbts.2020.09.009

Biondi Zoccai, G., Abbate, A., Frati, G., Gaudino, M., Romagnoli, E., & Sciarretta, S. (2020). Minerva Cardioangiologica: glancing backward, rushing forward. MINERVA CARDIOANGIOLOGICA, 68(1), 1-4. doi:10.23736/S0026-4725.19.05086-2

Biondi Zoccai, G., Gaudino, M., Romagnoli, E., Sciarretta, S., Abbate, A., & Frati, G. (2020). Italian cardiovascular expats: global leaders with Italian heartstrings. MINERVA CARDIOANGIOLOGICA, 68(3), 167-171. doi:10.23736/S0026-4725.20.05152-X

Biondi Zoccai, G., Frati, G., Romagnoli, E., Sciarretta, S., & Abbate, A. (2020). Final results of the ISCHEMIA trial: distinguishing mass media coverage from clinical interpretation. MINERVA CARDIOANGIOLOGICA, 68(1), 9-14. doi:10.23736/S0026-4725.19.05106-5

Nguyen, K., Chau, V. Q., Mauro, A. G., Durrant, D., Toldo, S., Abbate, A., . . . Salloum, F. N. (2020). Hydrogen Sulfide Therapy Suppresses Cofilin-2 and Attenuates Ischemic Heart Failure in a Mouse Model of Myocardial Infarction. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS, 25(5), 472-483. doi:10.1177/1074248420923542

Vecchie, A., Chiabrando, J. G., Dell, M. S., Bonaventura, A., Mauro, A. G., Wohlford, G., . . . Abbate, A. (2020). Clinical Presentation and Outcomes of Acute Pericarditis in a Large Urban Hospital in the United States of America. CHEST, 158(6), 2556-2567. doi:10.1016/j.chest.2020.07.039

Lombardi, M., Chiabrando, J. G., Vescovo, G. M., Bressi, E., Del Buono, M. G., Carbone, S., . . . Biondi Zoccai, G. (2020). Efficacy of different doses of omega-3 fatty acids on cardiovascular outcomes: rationale and design of a network meta-analysis. MINERVA CARDIOANGIOLOGICA, 68(1), 47-50. doi:10.23736/S0026-4725.19.05117-X

Bonaventura, A., Vecchie, A., Wang, T. S., Lee, E., Cremer, P. C., Carey, B., . . . Abbate, A. (2020). Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies. FRONTIERS IN IMMUNOLOGY, 11. doi:10.3389/fimmu.2020.01625

Carbone, S., Billingsley, H. E., Canada, J. M., Bressi, E., Rotelli, B., Kadariya, D., . . . Abbate, A. (2020). The effects of canagliflozin compared to sitagliptin on cardiorespiratory fitness in type 2 diabetes mellitus and heart failure with reduced ejection fraction: TheCANA-HFstudy. DIABETES-METABOLISM RESEARCH AND REVIEWS, 36(8). doi:10.1002/dmrr.3335

Lombardi, M., Chiabrando, J. G., Vescovo, G. M., Bressi, E., Del Buono, M. G., Carbone, S., . . . Dixon, D. L. (2020). Impact of Different Doses of Omega-3 Fatty Acids on Cardiovascular Outcomes: a Pairwise and Network Meta-analysis. CURRENT ATHEROSCLEROSIS REPORTS, 22(9). doi:10.1007/s11883-020-00865-5

Keen, L. I. I., Tan, A. Y., & Abbate, A. (2020). Inverse associations between parasympathetic activity and cognitive flexibility in African Americans: Preliminary findings. INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 155, 204-209. doi:10.1016/j.ijpsycho.2020.06.013

Arena, R., Canada, J. M., Popovic, D., Trankle, C. R., Del Buono, M. G., Lucas, A., & Abbate, A. (2020). Cardiopulmonary exercise testing - refining the clinical perspective by combining assessments. EXPERT REVIEW OF CARDIOVASCULAR THERAPY, 18(9), 563-576. doi:10.1080/14779072.2020.1806057

van Wezenbeek, J., Canada, J. M., Ravindra, K., Carbone, S., Kadariya, D., Trankle, C. R., . . . Abbate, A. (2020). Determinants of Cardiorespiratory Fitness in Patients with Heart Failure Across a Wide Range of Ejection Fractions. AMERICAN JOURNAL OF CARDIOLOGY, 125(1), 76-81. doi:10.1016/j.amjcard.2019.09.036

Wohlford, G. F., Buckley, L. F., Vecchie, A., Kadariya, D., Markley, R., Trankle, C. R., . . . Abbate, A. (2020). Acute Effects of Interleukin-1 Blockade Using Anakinra in Patients With Acute Pericarditis. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 76(1), 50-52. doi:10.1097/FJC.0000000000000847

Del Buono, M. G., Bonaventura, A., Vecchie, A., Wohlford, G. F., Dixon, D. L., Van Tassel, B. W., & Abbate, A. (2020). Sacubitril-Valsartan for the Treatment of Heart Failure: Time for a Paragon?. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 75(2), 105-107. doi:10.1097/FJC.0000000000000782

Wohlford, G. F., Van Tassell, B. W., Ravindra, K., & Abbate, A. (2020). COLCOT and CANTOS: piecing together the puzzle of inflammation and cardiovascular events. MINERVA CARDIOANGIOLOGICA, 68(1), 5-8. doi:10.23736/S0026-4725.19.05104-1

Billingsley, H. E., Dixon, D. L., Gipson, G., Abbate, A., & Carbone, S. (2020). Time restricted feeding: old tools, new packaging?. MINERVA CARDIOANGIOLOGICA, 68(6), 539-541. doi:10.23736/S0026-4725.20.05253-6

Canada, J. M., Thomas, G. K., Trankle, C. R., Carbone, S., Billingsley, H., Van Tassell, B. W., . . . Abbate, A. (2020). Increased C-reactive protein is associated with the severity of thoracic radiotherapy-induced cardiomyopathy. CARDIO-ONCOLOGY, 6(1). doi:10.1186/s40959-020-0058-1

Ricco, A., Slade, A., Canada, J. M., Grizzard, J., Dana, F., Gharai, L. R., . . . Weiss, E. (2020). Cardiac MRI utilizing late gadolinium enhancement (LGE) and T1 mapping in the detection of radiation induced heart disease. CARDIO-ONCOLOGY, 6(1). doi:10.1186/s40959-020-00061-z

Keen, L. I. I., Arias, A., Abbate, A., & Moeller, F. G. (2020). Heart Rate Variability as a Link Between Brain-Elicited Substance Cues and Substance Use Severity. BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING, 5(6), 560-561. doi:10.1016/j.bpsc.2020.04.010

Bittner, V. A., Szarek, M., Aylward, P. E., Bhatt, D. L., Diaz, R., Edelberg, J. M., . . . Ball, E. (2020). Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 75(2), 133-144. doi:10.1016/j.jacc.2019.10.057

Ma, L., Steinberg, J. L., Bjork, J. M., Wang, Q., Hettema, J. M., Abbate, A., & Moeller, F. G. (2020). Altered Effective Connectivity of Central Autonomic Network in Response to Negative Facial Expression in Adults With Cannabis Use Disorder. BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING, 5(1), 84-96. doi:10.1016/j.bpsc.2019.05.013

2019

Dixon, D. L., Wohlford, G. F., & Abbate, A. (2020). Inflammation and Hypertension Causal or Not?. HYPERTENSION, 75(2), 297-298. doi:10.1161/HYPERTENSIONAHA.119.14195

Canada, J. M., Trankle, C. R., Carbone, S., Buckley, L. F., de Chazal, M., Billingsley, H., . . . Abbate, A. (2020). Determinants of Cardiorespiratory Fitness Following Thoracic Radiotherapy in Lung or Breast Cancer Survivors. AMERICAN JOURNAL OF CARDIOLOGY, 125(6), 988-996. doi:10.1016/j.amjcard.2019.12.019

Roe, M. T., Li, Q. H., Bhatt, D. L., Bittner, V. A., Diaz, R., Goodman, S. G., . . . Zobouyan, I. (2019). Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes. CIRCULATION, 140(19), 1578-1589. doi:10.1161/CIRCULATIONAHA.119.042551

Mauro, A. G., Bonaventura, A., & Abbate, A. (2019). Drugs to Inhibit the NLRP3 Inflammasome: Not Always On Target. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 74(3), 225-227. doi:10.1097/FJC.0000000000000729

Trankle, C. R., Wohlford, G., Buckley, L. F., Kadariya, D., Ravindra, K., Markley, R., . . . Abbate, A. (2019). Alirocumab in Acute Myocardial Infarction: Results From the Virginia Commonwealth University Alirocumab Response Trial (VCU-AlirocRT). JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 74(3), 266-269. doi:10.1097/FJC.0000000000000706

Kron, J., Mauro, A. G., Bonaventura, A., Toldo, S., Salloum, F. N., Ellenbogen, K. A., & Abbate, A. (2019). Inflammasome Formation in Granulomas in Cardiac Sarcoidosis. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 12(9). doi:10.1161/CIRCEP.119.007582

Mishra, P. K., Adameova, A., Hill, J. A., Baines, C. P., Kang, P. M., Downey, J. M., . . . Matsui, T. (2019). Guidelines for evaluating myocardial cell death. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 317(5), H891-H922. doi:10.1152/ajpheart.00259.2019

Ray, K. K., Colhoun, H. M., Szarek, M., Baccara-Dinet, M., Bhatt, D. L., Bittner, V. A., . . . Zobouyan, I. (2019). Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial. LANCET DIABETES & ENDOCRINOLOGY, 7(8), 618-628. doi:10.1016/S2213-8587(19)30158-5

Bonaventura, A., Vecchie, A., Carbone, S., Montecucco, F., & Abbate, A. (2020). Comment on Hypoglycemia and hyperglycemia are risk factors for falls in the hospital population by Berra et al.. ACTA DIABETOLOGICA, 57(1), 109-110. doi:10.1007/s00592-019-01379-6

Steg, P. G., Szarek, M., Bhatt, D. L., Bittner, V. A., Bregeault, M. -F., Dalby, A. J., . . . Zobouyan, I. (2019). Effect of Alirocumab on Mortality After Acute Coronary Syndromes An Analysis of the ODYSSEY OUTCOMES Randomized Clinical Trial. CIRCULATION, 140(2), 103-112. doi:10.1161/CIRCULATIONAHA.118.038840

Del Buono, M. G., Arena, R., Borlaug, B. A., Carbone, S., Canada, J. M., Kirkman, D. L., . . . Abbate, A. (2019). Exercise Intolerance in Patients With Heart Failure. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 73(17), 2209-2225. doi:10.1016/j.jacc.2019.01.072

Patel, S. S., Lin, F. -P., Rodriguez, V. A., Bhati, C., John, B. V., Pence, T., . . . Siddiqui, M. S. (2019). The relationship between coronary artery disease and cardiovascular events early after liver transplantation. LIVER INTERNATIONAL, 39(7), 1363-1371. doi:10.1111/liv.14092

Bonaventura, A., Carbone, S., Dixon, D. L., Abbate, A., & Montecucco, F. (2019). Pharmacologic strategies to reduce cardiovascular disease in type 2 diabetes mellitus: focus on SGLT-2 inhibitors and GLP-1 receptor agonists. JOURNAL OF INTERNAL MEDICINE, 286(1), 16-31. doi:10.1111/joim.12890

Keen, L. I. I., Abbate, A., Blanden, G., Priddie, C., Moeller, F. G., & Rathore, M. (2019). Confirmed marijuana use and lymphocyte count in black people living with HIV. DRUG AND ALCOHOL DEPENDENCE, 198, 112-115. doi:10.1016/j.drugalcdep.2018.11.018

Everett, B. M., Cornel, J. H., Lainscak, M., Anker, S. D., Abbate, A., Thuren, T., . . . Ridker, P. M. (2019). Anti-Inflammatory Therapy With Canakinumab for the Prevention of Hospitalization for Heart Failure. CIRCULATION, 139(10), 1289-1299. doi:10.1161/CIRCULATIONAHA.118.038010

Trankle, C. R., Canada, J. M., Kadariya, D., Markley, R., De Chazal, H. M., Pinson, J., . . . Grinnan, D. (2019). IL-1 Blockade Reduces Inflammation in Pulmonary Arterial Hypertension and Right Ventricular Failure: A Single-Arm, Open-Label, Phase IB/II Pilot Study. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199(3), 381-384. doi:10.1164/rccm.201809-1631LE

Buckley, L. F., Canada, J. M., Carbone, S., Trankle, C. R., Kadariya, D., Billingsley, H., . . . Van Tassell, B. W. (2019). Potential role for interleukin-1 in the cardio-renal syndrome. EUROPEAN JOURNAL OF HEART FAILURE, 21(3), 385-+. doi:10.1002/ejhf.1403

Spinello, A., Vecile, E., Abbate, A., Dobrina, A., & Magistrato, A. (2019). How Can Interleukin-1 Receptor Antagonist Modulate Distinct Cell Death Pathways?. JOURNAL OF CHEMICAL INFORMATION AND MODELING, 59(1), 351-359. doi:10.1021/acs.jcim.8b00565

Mishra, P. K., Adameova, A., Hill, J. A., Baines, C. P., Kang, P. M., Downey, J. M., . . . Matsui, T. (2019). Guidelines for evaluating myocardial cell death (vol 317, pg H891, 2019). AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 317(6), H1390. doi:10.1152/ajpheart.zh4-2975-corr.2019

Gonzalez-Pacheco, H., Bojalil, R., Amezcua-Guerra, L. M., Sandoval, J., Eid-Lidt, G., Arias-Mendoza, A., . . . Martinez-Sanchez, C. (2019). Derivation and validation of a simple inflammation-based risk score system for predicting in-hospital mortality in acute coronary syndrome patients. JOURNAL OF CARDIOLOGY, 73(5), 416-424. doi:10.1016/j.jjcc.2018.11.010

Giuseppe Del Buono, M., Potere, N., Guido Chiabrando, J., Bressi, E., & Abbate, A. (2019). Takotsubo syndrome: diagnostic work-up and clues into differential diagnosis. CURRENT OPINION IN CARDIOLOGY, 34(6), 673-686. doi:10.1097/HCO.0000000000000672

Afeltra, A., Abbate, A., Valentini, G., & Giacomelli, R. (2019). Inflammation and Dysmetabolism in Systemic Autoimmune Diseases. JOURNAL OF IMMUNOLOGY RESEARCH, 2019. doi:10.1155/2019/5438287

Bussani, R., De-Giorgio, F., Pesel, G., Zandona, L., Sinagra, G., Grassi, S., . . . Silvestri, F. (2019). Overview and Comparison of Infectious Endocarditis and Non-infectious Endocarditis: A Review of 814 Autoptic Cases. IN VIVO, 33(5), 1565-1572. doi:10.21873/invivo.11638

Van Tassell, B. W., Westman, P., Trankle, C., Johns, S., Kadariya, D., Buckley, L., . . . Moeller, F. G. (2019). Noninvasive Hemodynamic Monitoring of Cocaine-Induced Changes in Cardiac Output and Systemic Vascular Resistance in Subjects With Chronic Cocaine Use Disorder. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 74(6), 528-534. doi:10.1097/FJC.0000000000000740

Abbate, A., & Booz, G. W. (2019). Cardiovascular Pharmacology of the NLRP3 Inflammasome. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 74(3), 173-174. doi:10.1097/FJC.0000000000000725

Carbone, S., Billingsley, H. E., Canada, J. M., Kadariya, D., de Chazal, H. M., Rotelli, B., . . . Abbate, A. (2019). Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Patients With Obesity and HFpEF The UFA-Preserved Pilot Study. JACC-BASIC TO TRANSLATIONAL SCIENCE, 4(4), 563-565. doi:10.1016/j.jacbts.2019.04.001

DeWilde, C., Carrington, J., Abbate, A., Burton, C. W., Bearman, G., & Salyer, J. (2019). Structural Stress and Otherness: How Do They Influence Psychological Stress?. JOURNAL OF TRANSCULTURAL NURSING, 30(5), 478-491. doi:10.1177/1043659618823915

Bonaventura, A., Wohlford, G. F., Vecchie, A., Van Tassel, B. W., & Abbate, A. (2019). In-Hospital Initiation of Sacubitril/Valsartan: A New PARADIGM for Acute Decompensated Heart Failure?. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 74(1), 1-3. doi:10.1097/FJC.0000000000000685

Canada, J. M., Evans, R. K., Abbate, A., Arena, R., Tang, D. G., Kasirajan, V., & Shah, K. B. (2019). Exercise Capacity in Patients with the Total Artificial Heart. ASAIO JOURNAL, 65(1), 36-42. doi:10.1097/MAT.0000000000000746

Potere, N., Del Buono, M. G., Mauro, A. G., Abbate, A., & Toldo, S. (2019). Low Density Lipoprotein Receptor-Related Protein-1 in Cardiac Inflammation and Infarct Healing. FRONTIERS IN CARDIOVASCULAR MEDICINE, 6. doi:10.3389/fcvm.2019.00051

Toldo, S., Mauro, A. G., Cutter, Z., Van Tassel, B. W., Mezzaroma, E., Del Buono, M. G., . . . Abbate, A. (2019). The NLRP3 Inflammasome Inhibitor, OLT1177 (Dapansutrile), Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 73(4), 215-222. doi:10.1097/FJC.0000000000000658

Potere, N., Del Buono, M. G., Niccoli, G., Crea, F., Toldo, S., & Abbate, A. (2019). Developing LRP1 Agonists into a Therapeutic Strategy in Acute Myocardial Infarction. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(3). doi:10.3390/ijms20030544

Keen, L. I. I., Abbate, A., Blanden, G., Priddie, C., Moeller, F. G., & Rathore, M. (2019). Confirmed Marijuana Use and Lymphocyte Count in Black People Living with HIV (Retraction of Vol 180, Pg 22, 2017). DRUG AND ALCOHOL DEPENDENCE, 198, 199. doi:10.1016/j.drugalcdep.2019.03.001

Potere, N., Toldo, S., & Abbate, A. (2019). Letter by Potere et al Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages". CIRCULATION, 139(16), 1979-1980. doi:10.1161/CIRCULATIONAHA.118.036486

Contaifer, D. J., Buckley, L. F., Wohlford, G., Kumar, N. G., Morriss, J. M., Ranasinghe, A. D., . . . Wijesinghe, D. S. (2019). Metabolic modulation predicts heart failure tests performance. PLOS ONE, 14(6). doi:10.1371/journal.pone.0218153

Billingsley, H. E., Rodriguez-Miguelez, P., Del Buono, M. G., Abbate, A., Lavie, C. J., & Carbone, S. (2019). Lifestyle Interventions with a Focus on Nutritional Strategies to Increase Cardiorespiratory Fitness in Chronic Obstructive Pulmonary Disease, Heart Failure, Obesity, Sarcopenia, and Frailty. NUTRIENTS, 11(12). doi:10.3390/nu11122849

Del Buono, M. G., Carbone, S., & Abbate, A. (2019). Letter by Del Buono et al Regarding Article, "A Simple, Evidence-Based Approach To Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction". CIRCULATION, 139(7), 990-991. doi:10.1161/CIRCULATIONAHA.118.038072

Goodman, S. G., Aylward, P. E., Szarek, M., Chumburidze, V., Bhatt, D. L., Bittner, V. A., . . . Ball, E. (2019). Effects of Alirocumab on Cardiovascular Events After Coronary Bypass Surgery. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 74(9), 1177-1186. doi:10.1016/j.jacc.2019.07.015

Szarek, M., Steg, P. G., DiCenso, D., Bhatt, D. L., Bittner, V. A., Budaj, A., . . . Zobouyan, I. (2019). Alirocumab Reduces Total Hospitalizations and Increases Days Alive and Out of Hospital in the ODYSSEY OUTCOMES Trial. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 12(11). doi:10.1161/CIRCOUTCOMES.119.005858

White, H. D., Steg, P. G., Szarek, M., Bhatt, D. L., Bittner, V. A., Diaz, R., . . . Ball, E. (2019). Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial. EUROPEAN HEART JOURNAL, 40(33), 2801-2809. doi:10.1093/eurheartj/ehz299

Jukema, J. W., Szarek, M., Zijlstra, L. E., de Silva, H. A., Bhatt, D. L., Bittner, V. A., . . . Zobouyan, I. (2019). Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome ODYSSEY OUTCOMES Trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 74(9), 1167-1176. doi:10.1016/j.jacc.2019.03.013

Szarek, M., White, H. D., Schwartz, G. G., Alings, M., Bhatt, D. L., Bittner, V. A., . . . Zobouyan, I. (2019). Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events The ODYSSEY OUTCOMES Trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 73(4), 387-396. doi:10.1016/j.jacc.2018.10.039

2018

Zuurbier, C. J., Abbate, A., Cabrera-Fuentes, H. A., Cohen, M. V., Collino, M., De Kleijn, D. P. V., . . . Davidson, S. M. (2019). Innate immunity as a target for acute cardioprotection. CARDIOVASCULAR RESEARCH, 115(7), 1131-1142. doi:10.1093/cvr/cvy304

Carbone, S., Mauro, A. G., Prestamburgo, A., Halquist, M. S., Narayan, P., Potere, N., . . . Toldo, S. (2018). An Orally Available NLRP3 Inflammasome Inhibitor Prevents Western Diet-Induced Cardiac Dysfunction in Mice. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 72(6), 303-307. doi:10.1097/FJC.0000000000000628

Canada, J. M., Abbate, A., Collen, R., Billingsley, H., Buckley, L. F., Carbone, S., . . . Siddiqui, M. S. (2019). Relation of Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease to Left Ventricular Diastolic Function and Exercise Tolerance. AMERICAN JOURNAL OF CARDIOLOGY, 123(3), 466-473. doi:10.1016/j.amjcard.2018.10.027

Medina de Chazal, H., Del Buono, M. G., Keyser-Marcus, L., Ma, L., Moeller, F. G., Berrocal, D., & Abbate, A. (2018). Stress Cardiomyopathy Diagnosis and Treatment JACC State-of-the-Art Review. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 72(16), 1955-1971. doi:10.1016/j.jacc.2018.07.072

Toldo, S., Mauro, A. G., Cutter, Z., & Abbate, A. (2018). Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 315(6), H1553-H1568. doi:10.1152/ajpheart.00158.2018

Del Buono, M. G., Buckley, L., & Abbate, A. (2018). Primary and Secondary Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction. AMERICAN JOURNAL OF CARDIOLOGY, 122(9), 1578-1587. doi:10.1016/j.amjcard.2018.07.012

Van Tassell, B. W., Trankle, C. R., Canada, J. M., Carbone, S., Buckley, L., Kadariya, D., . . . Abbate, A. (2018). IL-1 Blockade in Patients With Heart Failure With Preserved Ejection Fraction: Results From DHART2. CIRCULATION-HEART FAILURE, 11(8). doi:10.1161/CIRCHEARTFAILURE.118.005036

Trankle, C. R., Canada, J. M., Cei, L., Abouzaki, N., Oddi-Erdle, C., Kadariya, D., . . . Abbate, A. (2018). Usefulness of Canakinumab to Improve Exercise Capacity in Patients With Long-Term Systolic Heart Failure and Elevated C-Reactive Protein. AMERICAN JOURNAL OF CARDIOLOGY, 122(8), 1366-1370. doi:10.1016/j.amjcard.2018.07.002

Buckley, L. F., Carbone, S., Trankle, C. R., Canada, J. M., Erdle, C. O., Regan, J. A., . . . Van Tassell, B. W. (2018). Effect of Interleukin-1 Blockade on Left Ventricular Systolic Performance and Work: A Post Hoc Pooled Analysis of 2 Clinical Trials. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 72(1), 68-70. doi:10.1097/FJC.0000000000000591

Abouzaki, N. A., Christopher, S., Trankle, C., Van Tassell, B. W., Carbone, S., Mauro, A. G., . . . Abbate, A. (2018). Inhibiting the Inflammatory Injury After Myocardial Ischemia Reperfusion With Plasma-Derived Alpha-1 Antitrypsin: A Post Hoc Analysis of the VCU-α1RT Study. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 71(6), 375-379. doi:10.1097/FJC.0000000000000583

Buckley, L. F., & Abbate, A. (2018). Interleukin-1 blockade in cardiovascular diseases: a clinical update. EUROPEAN HEART JOURNAL, 39(22), 2063-+. doi:10.1093/eurheartj/ehy128

Abbate, A., & Van Tassell, B. W. (2018). Levosimendan in Advanced Heart Failure: Where Do We Stand?. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 71(3), 127-128. doi:10.1097/FJC.0000000000000539

Seropian, I. M., Gonzalez, G. E., Maller, S. M., Berrocal, D. H., Abbate, A., & Rabinovich, G. A. (2018). Galectin-1 as an Emerging Mediator of Cardiovascular Inflammation: Mechanisms and Therapeutic Opportunities. MEDIATORS OF INFLAMMATION, 2018. doi:10.1155/2018/8696543

Buckley, L. F., & Abbate, A. (2018). Interleukin-1 Blockade in Cardiovascular Diseases: From Bench to Bedside. BIODRUGS, 32(2), 111-118. doi:10.1007/s40259-018-0274-5

Carbone, S., Dixon, D. L., & Abbate, A. (2018). Treatment of Hypertension to Prevent and Treat Heart Failure in Diabetic Patients Should Include Sodium Glucose Co-Transporter 2 Inhibitors. JACC-HEART FAILURE, 6(1), 85. doi:10.1016/j.jchf.2017.07.008

Carbone, S., Billingsley, H. E., & Abbate, A. (2018). The Mediterranean Diet to Treat Heart Failure A Potentially Powerful Tool in the Hands of Providers. JACC-HEART FAILURE, 6(3), 264. doi:10.1016/j.jchf.2017.12.008

Torrado, J., Buckley, L., Duran, A., Trujillo, P., Toldo, S., Raleigh, J. V., . . . Guzman, L. A. (2018). Restenosis, Stent Thrombosis, and Bleeding Complications Navigating Between Scylla and Charybdis. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 71(15), 1676-1695. doi:10.1016/j.jacc.2018.02.023

Carbone, S., Mauro, A. G., Toldo, S., & Abbate, A. (2018). Diet-Induced Obesity HFpEF Murine Models. JACC-BASIC TO TRANSLATIONAL SCIENCE, 3(1), 157. doi:10.1016/j.jacbts.2018.01.004

Carbone, S., Dixon, D. L., Buckley, L. F., & Abbate, A. (2018). Glucose-Lowering Therapies for Cardiovascular Risk Reduction in Type 2 Diabetes Mellitus: State-of-the-Art Review. MAYO CLINIC PROCEEDINGS, 93(11), 1629-1647. doi:10.1016/j.mayocp.2018.07.018

Carbone, S., Canada, J. M., Billingsley, H. E., Kadariya, D., Dixon, D. L., Trankle, C. R., . . . Abbate, A. (2018). Effects of empagliflozin on cardiorespiratory fitness and significant interaction of loop diuretics. DIABETES OBESITY & METABOLISM, 20(8), 2014-2018. doi:10.1111/dom.13309

Carbone, S., Canada, J. M., & Abbate, A. (2018). Letter by Carbone et al Regarding Article, "Evidence Supporting the Existence of a Distinct Obese Phenotype of Heart Failure With Preserved Ejection Fraction". CIRCULATION, 137(4), 414-415. doi:10.1161/CIRCULATIONAHA.117.030432

Buckley, L. F., Canada, J. M., Del Buono, M. G., Carbone, S., Trankle, C. R., Billingsley, H., . . . Abbate, A. (2018). Low NT-proBNP levels in overweight and obese patients do not rule out a diagnosis of heart failure with preserved ejection fraction. ESC HEART FAILURE, 5(2), 372-378. doi:10.1002/ehf2.12235

Buckley, L. F., Viscusi, M. M., Van Tassell, B., & Abbate, A. (2018). Interleukin-1 blockade for the treatment of pericarditis. EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY, 4(1), 46-53. doi:10.1093/ehjcvp/pvx018

Carbone, S., Billingsley, H., & Abbate, A. (2018). Associations of fats and carbohydrates with cardiovascular disease and mortality-PURE and simple?. LANCET, 391(10131), 1679. doi:10.1016/S0140-6736(18)30799-2

Del Buono, M., Abbate, A., & Toldo, S. (2018). Interplay of inflammation, oxidative stress and cardiovascular disease in rheumatoid arthritis. HEART, 104(24), 1991-1992. doi:10.1136/heartjnl-2018-313313

Van Tassell, B. W., Lipinski, M. J., Appleton, D., Roberts, C. S., Kontos, M. C., Abouzaki, N., . . . Abbate, A. (2018). Rationale and design of the Virginia Commonwealth University-Anakinra Remodeling Trial-3 (VCU-ART3): A randomized, placebo-controlled, double-blinded, multicenter study. CLINICAL CARDIOLOGY, 41(8), 1004-1008. doi:10.1002/clc.22988

van Wezenbeek, J., Canada, J. M., Ravindra, K., Carbone, S., Trankle, C. R., Kadariya, D., . . . Abbate, A. (2018). C-Reactive Protein and N-Terminal Pro-brain Natriuretic Peptide Levels Correlate With Impaired Cardiorespiratory Fitness in Patients With Heart Failure Across a Wide Range of Ejection Fraction. FRONTIERS IN CARDIOVASCULAR MEDICINE, 5. doi:10.3389/fcvm.2018.00178

Del Buono, M., & Abbate, A. (2018). Circulating cardiodepressant factors in takotsubo syndrome: An "angle" that needs to be explored further Response. AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 210, 82. doi:10.1016/j.autneu.2017.12.002

Quader, M., Toldo, S., Torrado, J., Mishra, S., Mauro, A. G., Mezzaroma, E., . . . Mangino, M. (2018). Determination of Optimal Coronary Flow for the Preservation of "Donation after Circulatory Death" in Murine Heart Model. ASAIO JOURNAL, 64(2), 225-231. doi:10.1097/MAT.0000000000000630

Chandrakumaran, A., Malik, M., Stevens, M. P., & Abbate, A. (2018). A case report of locally invasive Aspergillus fumigatus infection in a patient on canakinumab. EUROPEAN HEART JOURNAL-CASE REPORTS, 2(3). doi:10.1093/ehjcr/yty098

Del Buono, M. G., Carbone, S., & Abbate, A. (2018). Comment on Stiermaier et al. Prevalence and Prognostic Impact of Diabetes in Takotsubo Syndrome: Insights From the International, Multicenter GEIST Registry. Diabetes Care 2018;41:1084-1088. DIABETES CARE, 41(7), E121. doi:10.2337/dc18-0442

Schwartz, G. G., Steg, P. G., Szarek, M., Bhatt, D. L., Bittner, V. A., Diaz, R., . . . Ball, E. (2018). Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome. NEW ENGLAND JOURNAL OF MEDICINE, 379(22), 2097-2107. doi:10.1056/NEJMoa1801174

Fulp, J., He, L., Toldo, S., Jiang, Y., Boice, A., Guo, C., . . . Zhang, S. (2018). Structural Insights of Benzenesulfonamide Analogues as NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization. JOURNAL OF MEDICINAL CHEMISTRY, 61(12), 5412-5423. doi:10.1021/acs.jmedchem.8b00733

Patel, S. S., Nabi, E., Guzman, L., Abbate, A., Bhati, C., Stravitz, R. T., . . . Siddiqui, M. S. (2018). Coronary artery disease in decompensated patients undergoing liver transplantation evaluation. LIVER TRANSPLANTATION, 24(3), 333-342. doi:10.1002/lt.25012

2017

Toldo, S., & Abbate, A. (2018). The NLRP3 inflammasome in acute myocardial infarction. NATURE REVIEWS CARDIOLOGY, 15(4), 203-214. doi:10.1038/nrcardio.2017.161

Dixon, D. L., Salgado, T. M., & Abbate, A. (2017). Pharmacists as Integral Members of the Cardiovascular Team. JAMA CARDIOLOGY, 2(11), 1279-1280. doi:10.1001/jamacardio.2017.2795

Van Tassell, B. W., Canada, J., Carbone, S., Trankle, C., Buckley, L., Erdle, C. O., . . . Abbate, A. (2017). Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure Results From REDHART (Recently Decompensated Heart Failure Anakinra Response Trial). CIRCULATION-HEART FAILURE, 10(11). doi:10.1161/CIRCHEARTFAILURE.117.004373

Carbone, S., Canada, J. M., Buckley, L. F., Trankle, C. R., Billingsley, H. E., Dixon, D. L., . . . Abbate, A. (2017). Dietary Fat, Sugar Consumption, and Cardiorespiratory Fitness in Patients With Heart Failure With Preserved Ejection Fraction.. JACC. Basic to translational science, 2(5), 513-525. doi:10.1016/j.jacbts.2017.06.009

Toldo, S., Austin, D., Mauro, A. G., Mezzaroma, E., Van Tassell, B. W., Marchetti, C., . . . Abbate, A. (2017). Low-Density Lipoprotein Receptor-Related Protein-1 Is a Therapeutic Target in Acute Myocardial Infarction.. JACC. Basic to translational science, 2(5), 561-574. doi:10.1016/j.jacbts.2017.05.007

Canada, J. M., Trankle, C. R., Buckley, L. F., Carbone, S., Abouzaki, N. A., Kadariya, D., . . . Abbate, A. (2017). Severely Impaired Cardiorespiratory Fitness in Patients With Recently Decompensated Systolic Heart Failure. AMERICAN JOURNAL OF CARDIOLOGY, 120(10), 1854-1857. doi:10.1016/j.amjcard.2017.07.099

Toldo, S., Van Tassell, B. W., & Abbate, A. (2017). Interleukin-1 Blockade in Acute Myocardial Infarction and Heart Failure: Getting Closer and Closer.. JACC. Basic to translational science, 2(4), 431-433. doi:10.1016/j.jacbts.2017.07.006

Gomez-Arroyo, J., Voelkel, N. F., Huizar, J. F., & Abbate, A. (2017). Targeting Neurohormonal Activation in Pulmonary Arterial Hypertension: Putting the Puzzle Together.. JACC. Basic to translational science, 2(1), 36-38. doi:10.1016/j.jacbts.2016.11.003

Donnino, M. W., Liu, X., Andersen, L. W., Rittenberger, J. C., Abella, B. S., Gaieski, D. F., . . . Callaway, C. W. (2017). Characterization of mitochondrial injury after cardiac arrest (COMICA). RESUSCITATION, 113, 56-62. doi:10.1016/j.resuscitation.2016.12.029

Carbone, S., Lee, P. J. H., Mauro, A. G., Mezzaroma, E., Buzzetti, R., Van Tassell, B., . . . Toldo, S. (2017). Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse. NUTRITION & DIABETES, 7. doi:10.1038/nutd.2017.1

Trankle, C., Canada, J. M., Buckley, L., Carbone, S., Dixon, D., Arena, R., . . . Abbate, A. (2017). Impaired myocardial relaxation with exercise determines peak aerobic exercise capacity in heart failure with preserved ejection fraction. ESC HEART FAILURE, 4(3), 351-355. doi:10.1002/ehf2.12147

Abbate, A. (2017). Why the CANTOS Is a Game Changer in Cardiovascular Medicine. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 70(6), 353-355.

Sun, X. -Q., Abbate, A., & Bogaard, H. -J. (2017). Role of cardiac inflammation in right ventricular failure. CARDIOVASCULAR RESEARCH, 113(12), 1441-1452. doi:10.1093/cvr/cvx159

Baker, W. L., Buckley, L. F., Kelly, M. S., Bucheit, J. D., Parod, E. D., Brown, R., . . . Dixon, D. L. (2017). Effects of Sodium-Glucose Cotransporter 2 Inhibitors on 24-Hour Ambulatory Blood Pressure: A Systematic Review and Meta-Analysis. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 6(5). doi:10.1161/JAHA.117.005686

Van Tassell, B. W., Buckley, L. F., Carbone, S., Trankle, C. R., Canada, J. M., Dixon, D. L., . . . Abbate, A. (2017). Interleukin-1 blockade in heart failure with preserved ejection fraction: rationale and design of the Diastolic Heart Failure Anakinra Response Trial 2 (D-HART2). CLINICAL CARDIOLOGY, 40(9), 626-632. doi:10.1002/clc.22719

Dixon, D. L., Buckley, L. F., Trankle, C. R., Kadariya, D., & Abbate, A. (2017). Clinical utility of evolocumab in the management of hyperlipidemia: patient selection and follow-up. DRUG DESIGN DEVELOPMENT AND THERAPY, 11, 2121-2129. doi:10.2147/DDDT.S114091

Keen, L. I. I., Abbate, A., Blanden, G., Priddie, C., Moeller, F. G., & Rathore, M. (2017). Confirmed marijuana use and lymphocyte count in black people living with HIV (Retracted Article). DRUG AND ALCOHOL DEPENDENCE, 180, 22-25. doi:10.1016/j.drugalcdep.2017.07.026

Sonnino, C., Van Tassell, B. W., Toldo, S., Del Buono, M. G., Moeller, F. G., & Abbate, A. (2017). Lack of soluble circulating cardiodepressant factors in takotsubo cardiomyopathy. AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 208, 170-172. doi:10.1016/j.autneu.2017.10.010

Mauro, A. G., Mezzaroma, E., Torrado, J., Kundur, P., Joshi, P., Stroud, K., . . . Toldo, S. (2017). Reduction of Myocardial Ischemia-Reperfusion Injury by Inhibiting Interleukin-1 Alpha. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 69(3), 156-160. doi:10.1097/FJC.0000000000000452

Del Buono, M. G., O'Quinn, M. P., Garcia, P., Gerszten, E., Roberts, C., Moeller, F. G., & Abbate, A. (2017). Cardiac arrest due to ventricular fibrillation in a 23-year-old woman with broken heart syndrome. CARDIOVASCULAR PATHOLOGY, 30, 78-81. doi:10.1016/j.carpath.2017.06.007

Cardona-Guarache, R., Padala, S. K., Velazco-Davila, L., Cassano, A., Abbate, A., Ellenbogen, K. A., & Koneru, J. N. (2017). Stellate ganglion blockade and bilateral cardiac sympathetic denervation in patients with life-threatening ventricular arrhythmias. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 28(8), 903-908. doi:10.1111/jce.13249

Raleigh, J. V., Mauro, A. G., Devarakonda, T., Marchetti, C., He, J., Kim, E., . . . Salloum, F. N. (2017). Reperfusion therapy with recombinant human relaxin-2 (Serelaxin) attenuates myocardial infarct size and NLRP3 inflammasome following ischemia/reperfusion injury via eNOS-dependent mechanism. CARDIOVASCULAR RESEARCH, 113(6), 609-619. doi:10.1093/cvr/cvw246

2016

Rabender, C., Mezzaroma, E., Mauro, A. G., Mullangi, R., Abbate, A., Anscher, M., . . . Mikkelsen, R. (2016). IPW-5371 Proves Effective as a Radiation Countermeasure by Mitigating Radiation-Induced Late Effects. RADIATION RESEARCH, 186(5), 478-488. doi:10.1667/RR14403.2

Trankle, C., Thurber, C. J., Toldo, S., & Abbate, A. (2016). Mitochondrial Membrane Permeability Inhibitors in Acute Myocardial Infarction: Still Awaiting Translation.. JACC. Basic to translational science, 1(6), 524-535. doi:10.1016/j.jacbts.2016.06.012

Serrano, N. A., Mikkelsen, R., Canada, J., Mezzaroma, E., Weiss, E., & Abbate, A. (2016). Biomarkers of cardiac injury in patients undergoing thoracic radiation therapy. INTERNATIONAL JOURNAL OF CARDIOLOGY, 223, 507-509. doi:10.1016/j.ijcard.2016.08.263

Schatz, A., Trankle, C., Yassen, A., Chipko, C., Rajab, M., Abouzaki, N., & Abbate, A. (2016). Resolution of pericardial constriction with Anakinra in a patient with effusive-constrictive pericarditis secondary to rheumatoid arthritis. INTERNATIONAL JOURNAL OF CARDIOLOGY, 223, 215-216. doi:10.1016/j.ijcard.2016.08.131

Van Tassell, B. W., Abouzaki, N. A., Erdle, C. O., Carbone, S., Trankle, C. R., Melchior, R. D., . . . Abbate, A. (2016). Interleukin-1 Blockade in Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 67(6), 544-551. doi:10.1097/FJC.0000000000000378

Peberdy, M. A., Andersen, L. W., Abbate, A., Thacker, L. R., Gaieski, D., Abella, B. S., . . . Donnino, M. (2016). Inflammatory markers following resuscitation from out-of-hospital cardiac arrest-A prospective multicenter observational study. RESUSCITATION, 103, 117-124. doi:10.1016/j.resuscitation.2016.01.006

Toldo, S., Marchetti, C., & Abbate, A. (2016). Re. "NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective". BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 470(4), 811-812. doi:10.1016/j.bbrc.2016.01.088

Zardi, E. M., Zardi, D. M., Chin, D., Sonnino, C., Dobrina, A., & Abbate, A. (2016). Cirrhotic cardiomyopathy in the pre- and post-liver transplantation phase. JOURNAL OF CARDIOLOGY, 67(1-2), 125-130. doi:10.1016/j.jjcc.2015.04.016

Casale, M., Mangiacapra, F., Bressi, E., Pace, A., Sabatino, L., Moffa, A., . . . Salvinelli, F. (2016). Idiopathic sensorineural hearing loss is associated with endothelial dysfunction. IJC HEART & VASCULATURE, 12, 32-33. doi:10.1016/j.ijcha.2016.05.001

Carbone, S., Arena, R., & Abbate, A. (2016). Lack of Benefit for Liraglutide in Heart Failure. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 316(22), 2429. doi:10.1001/jama.2016.15387

Chawla, R., Zukas, A. M., Pitcher, J. H., Trankle, C., Brath, L., & Abbate, A. (2016). Autonomic instability and asystole: Broadening the differential diagnosis of cardiac arrhythmias. INTERNATIONAL JOURNAL OF CARDIOLOGY, 220, 665-667. doi:10.1016/j.ijcard.2016.06.297

Dixon, D. L., Trankle, C., Buckley, L., Parod, E., Carbone, S., Van Tassell, B. W., & Abbate, A. (2016). A review of PCSK9 inhibition and its effects beyond LDL receptors. JOURNAL OF CLINICAL LIPIDOLOGY, 10(5), 1073-1080. doi:10.1016/j.jacl.2016.07.004

Seropian, I. M., Sonnino, C., Van Tassell, B. W., Biasucci, L. M., & Abbate, A. (2016). Inflammatory markers in ST-elevation acute myocardial infarction. EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, 5(4), 382-395. doi:10.1177/2048872615568965

Canada, J. M., Fronk, D. T., Cei, L. F., Carbone, S., Erdle, C. O., Abouzaki, N. A., . . . Abbate, A. (2016). Usefulness of C-Reactive Protein Plasma Levels to Predict Exercise Intolerance in Patients With Chronic Systolic Heart Failure. AMERICAN JOURNAL OF CARDIOLOGY, 117(1), 116-120. doi:10.1016/j.amjcard.2015.10.020

Carl, D. E., Ghosh, S. S., Gehr, T. W. B., Abbate, A., Toldo, S., & Sanyal, A. J. (2016). A model of acute kidney injury in mice with cirrhosis and infection. LIVER INTERNATIONAL, 36(6), 865-873. doi:10.1111/liv.13023

Carbone, S., Canada, J. M., Buckley, L. F., Trankle, C. R., Dixon, D. L., Buzzetti, R., . . . Abbate, A. (2016). Obesity Contributes to Exercise Intolerance in Heart Failure With Preserved Ejection Fraction. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 68(22), 2487-2488. doi:10.1016/j.jacc.2016.08.072

Raleigh, J. M. V., Toldo, S., Das, A., Abbate, A., & Salloum, F. N. (2016). Relaxin' the Heart: A Novel Therapeutic Modality. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS, 21(4), 353-362. doi:10.1177/1074248415617851

Gomez-Arroyo, J., Abbate, A., & Voelkel, N. F. (2016). Pulmonary arterial hypertension and the Enigma code of smouldering inflammation. EUROPEAN RESPIRATORY JOURNAL, 48(2), 305-307. doi:10.1183/13993003.00996-2016

Farr, G., Shah, K., Markley, R., Abbate, A., Salloum, F. N., & Grinnan, D. (2016). Development of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction. PROGRESS IN CARDIOVASCULAR DISEASES, 59(1), 52-58. doi:10.1016/j.pcad.2016.06.002

Cardona-Guarache, R., Pozen, J., Jahangiri, A., Koneru, J., Shepard, R., Roberts, C., . . . Cassano, A. (2016). Thoracic Sympathectomy for Severe Refractory Multivessel Coronary Artery Spasm. AMERICAN JOURNAL OF CARDIOLOGY, 117(1), 159-161. doi:10.1016/j.amjcard.2015.10.018

Toldo, S., Quader, M., Salloum, F. N., Mezzaroma, E., & Abbate, A. (2016). Targeting the Innate Immune Response to Improve Cardiac Graft Recovery after Heart Transplantation: Implications for the Donation after Cardiac Death. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 17(6). doi:10.3390/ijms17060958

Dixon, D. L., Carbone, S., & Abbate, A. (2016). Letter by Dixon et al Regarding Article, "Watching Television and Risk of Mortality From Pulmonary Embolism Among Japanese Men and Women: The JACC Study (Japan Collaborative Cohort)". CIRCULATION, 134(21), E499-E500. doi:10.1161/CIRCULATIONAHA.116.024740

Shah, R. M., Patel, D., Abbate, A., Cowley, M. J., & Jovin, I. S. (2016). Comparison of transradial coronary procedures via right radial versus left radial artery approach: A meta-analysis. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 88(7), 1027-1033. doi:10.1002/ccd.26519

Toldo, S., Mauro, A. G., Marchetti, C., Rose, S. W., Mezzaroma, E., Van Tassell, B. W., . . . Abbate, A. (2016). Recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury After Ischemia-Reperfusion Independent of Elastase Inhibition. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 68(1), 27-32. doi:10.1097/FJC.0000000000000383

Toldo, S., Marchetti, C., Mauro, A. G., Chojnacki, J., Mezzaroma, E., Carbone, S., . . . Abbate, A. (2016). Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia-reperfusion in the mouse. INTERNATIONAL JOURNAL OF CARDIOLOGY, 209, 215-220. doi:10.1016/j.ijcard.2016.02.043

2015

Regan, J. A., Mauro, A. G., Carbone, S., Marchetti, C., Gill, R., Mezzaroma, E., . . . Toldo, S. (2015). A mouse model of heart failure with preserved ejection fraction due to chronic infusion of a low subpressor dose of angiotensin II. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 309(5), H771-H778. doi:10.1152/ajpheart.00282.2015

Marchetti, C., Toldo, S., Chojnacki, J., Mezzaroma, E., Liu, K., Salloum, F. N., . . . Abbate, A. (2015). Pharmacologic Inhibition of the NLRP3 Inflammasome Preserves Cardiac Function After Ischemic and Nonischemic Injury in the Mouse. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 66(1), 1-8. doi:10.1097/FJC.0000000000000247

Mezzaroma, E., Mikkelsen, R. B., Toldo, S., Mauro, A. G., Sharma, K., Marchetti, C., . . . Abbate, A. (2015). Role of Interleukin-1 in Radiation-Induced Cardiomyopathy. MOLECULAR MEDICINE, 21, 210-218. doi:10.2119/molmed.2014.00243

Al-Husseini, A., Kraskauskas, D., Mezzaroma, E., Nordio, A., Farkas, D., Drake, J. I., . . . Voelkel, N. F. (2015). Vascular endothelial growth factor receptor 3 signaling contributes to angioobliterative pulmonary hypertension. PULMONARY CIRCULATION, 5(1), 101-116. doi:10.1086/679704

Van Tassell, B. W., Raleigh, J. M. V., & Abbate, A. (2015). Targeting interleukin-1 in heart failure and inflammatory heart disease.. Current heart failure reports, 12(1), 33-41. doi:10.1007/s11897-014-0231-7

Cannillo, M., D'Ascenzo, F., Marra, W. G., Cerrato, E., Calcagno, A., Omede, P., . . . Gaita, F. (2015). Heart failure in patients with human immunodeficiency virus: a review of the literature. JOURNAL OF CARDIOVASCULAR MEDICINE, 16(5), 383-389. doi:10.2459/JCM.0000000000000168

D'Ascenzo, F., Cerrato, E., Calcagno, A., Grossomarra, W., Ballocca, F., Omede, P., . . . Gaita, F. (2015). High prevalence at computed coronary tomography of non-calcified plaques in asymptomatic HIV patients treated with HAART: A meta-analysis. ATHEROSCLEROSIS, 240(1), 197-204. doi:10.1016/j.atherosclerosis.2015.03.019

D'Ascenzo, F., Quadri, G., Cerrato, E., Calcagno, A., Omede, P., Marra, W. G., . . . Gaita, F. (2015). A meta-analysis investigating incidence and features of stroke in HIV-infected patients in the highly active antiretroviral therapy era. JOURNAL OF CARDIOVASCULAR MEDICINE, 16(12), 839-843. doi:10.2459/JCM.0b013e328365ca31

Cerrato, E., Calcagno, A., D'Ascenzo, F., Biondi-Zoccai, G., Mancone, M., Marra, W. G., . . . Gaita, F. (2015). Cardiovascular disease in HIV patients: from bench to bedside and backwards. OPEN HEART, 2(1). doi:10.1136/openhrt-2014-000174

Biondi-Zoccai, G., Cerrato, E., Peruzzi, M., D'Ascenzo, F., De Falco, E., Chimenti, I., . . . Frati, G. (2015). An International Survey on Taking Up a Career in Cardiovascular Research: Opportunities and Biases toward Would-Be Physician-Scientists. PLOS ONE, 10(7). doi:10.1371/journal.pone.0131900

Peruzzi, M., De Falco, E., Abbate, A., Biondi-Zoccai, G., Chimenti, I., Lotrionte, M., . . . Frati, G. (2015). State of the Art on the Evidence Base in Cardiac Regenerative Therapy: Overview of 41 Systematic Reviews. BIOMED RESEARCH INTERNATIONAL, 2015. doi:10.1155/2015/613782

Biondi-Zoccai, G., Wu, Y., Serrano, C. V. J., Frati, G., Agostoni, P., & Abbate, A. (2015). Aspirin underuse, non-compliance or cessation: Definition, extent, impact and potential solutions in the primary and secondary prevention of cardiovascular disease. INTERNATIONAL JOURNAL OF CARDIOLOGY, 182, 148-154. doi:10.1016/j.ijcard.2014.12.091

Biondi-Zoccai, G., Abbate, A., Benedetto, U., Palmerini, T., D'Ascenzo, F., & Frati, G. (2015). Network meta-analysis for evidence synthesis: What is it and why is it posed to dominate cardiovascular decision making?. INTERNATIONAL JOURNAL OF CARDIOLOGY, 182, 309-314. doi:10.1016/j.ijcard.2015.01.023

Peruzzi, M., Biondi-Zoccai, G., Abbate, A., Giordano, A., & Frati, G. (2015). Which Comes First, the Phoenix or the Flame? Reflections on the Role of Inflammation in Patients Undergoing Lower Limb Revascularization for Peripheral Artery Disease. JOURNAL OF ENDOVASCULAR THERAPY, 22(2), 240-242. doi:10.1177/1526602815573217

Biondi-Zoccai, G., D'Ascenzo, F., Frati, G., & Abbate, A. (2015). What the meta analyses teaches us: merits and limits. GIORNALE ITALIANO DI CARDIOLOGIA, 16(9), 469-474. doi:10.1714/1988.21516

Ballocca, F., D'Ascenzo, F., Moretti, C., Omede, P., Cerrato, E., Barbero, U., . . . Gaita, F. (2015). Predictors of cardiovascular events in patients with systemic lupus erythematosus (SLE): a systematic review and meta-analysis. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 22(11), 1435-1441. doi:10.1177/2047487314546826

Biondi-Zoccai, G., Frati, G., & Abbate, A. (2015). Noncompliance and Cessation of Dual Antiplatelet Therapy After Coronary Stenting Looking at the Speck Rather Than Noticing the Log?. JACC-CARDIOVASCULAR INTERVENTIONS, 8(3), 411-413. doi:10.1016/j.jcin.2014.12.005

Seropian, I. M., & Abbate, A. (2015). Letter by Seropian and Abbate Regarding Article, "Effect of Tumor Necrosis Factor Inhibitor Treatment on Proximal Right Coronary Chronic Total Occlusion in a Patient With Rheumatoid Arthritis". CIRCULATION, 132(13), E162. doi:10.1161/CIRCULATIONAHA.115.015865

Kron, J., Ellenbogen, K., & Abbate, A. (2015). Recurrent ventricular fibrillation in a young female carrying a previously unidentified RyR2 gene mutation. INTERNATIONAL JOURNAL OF CARDIOLOGY, 201, 222-224. doi:10.1016/j.ijcard.2015.08.044

Gomez-Arroyo, J., Sakagami, M., Syed, A. A., Farkas, L., Van Tassell, B., Kraskauskas, D., . . . Voelkel, N. F. (2015). Iloprost reverses established fibrosis in experimental right ventricular failure. EUROPEAN RESPIRATORY JOURNAL, 45(2), 449-462. doi:10.1183/09031936.00188013

Abbate, A., Van Tassell, B. W., Canada, J. M., Dixon, D. L., Arena, R. A., & Biondi-Zoccai, G. (2015). Pharmacologic and Surgical Interventions to Improve Functional Capacity in Heart Failure. HEART FAILURE CLINICS, 11(1), 117-+. doi:10.1016/j.hfc.2014.08.005

Toldo, S., & Abbate, A. (2015). Diastolic dysfunction in chronic hypoxia: IL-18 provides the elusive link. ACTA PHYSIOLOGICA, 213(2), 298-300. doi:10.1111/apha.12403

Abbate, A., & Dinarello, C. A. (2015). Anti-inflammatory therapies in acute coronary syndromes: is IL-1 blockade a solution?. EUROPEAN HEART JOURNAL, 36(6), 337-339. doi:10.1093/eurheartj/ehu369

Abbate, A., Kontos, M. C., Abouzaki, N. A., Melchior, R. D., Thomas, C., Van Tassell, B. W., . . . Biondi-Zoccai, G. (2015). Comparative Safety of Interleukin-1 Blockade With Anakinra in Patients With ST-Segment Elevation Acute Myocardial Infarction (from the VCU-ART and VCU-ART2 Pilot Studies). AMERICAN JOURNAL OF CARDIOLOGY, 115(3), 288-292. doi:10.1016/j.amjcard.2014.11.003

Shah, K. B., Mauro, A. G., Flattery, M., Toldo, S., & Abbate, A. (2015). Formation of the inflammasome during cardiac allograft rejection. INTERNATIONAL JOURNAL OF CARDIOLOGY, 201, 328-330. doi:10.1016/j.ijcard.2015.08.070

Abbate, A., Van Tassell, B. W., Christopher, S., Abouzaki, N. A., Sonnino, C., Oddi, C., . . . Dinarello, C. A. (2015). Effects of Prolastin C (Plasma-Derived Alpha-1 Antitrypsin) on the Acute Inflammatory Response in Patients With ST-Segment Elevation Myocardial Infarction (from the VCU-Alpha 1-RT Pilot Study). AMERICAN JOURNAL OF CARDIOLOGY, 115(1), 8-12. doi:10.1016/j.amjcard.2014.09.043

Abbate, A., Arena, R., Abouzaki, N., Van Tassell, B. W., Canada, J., Shah, K., . . . Voelkel, N. F. (2015). Heart failure with preserved ejection fraction: Refocusing on diastole. INTERNATIONAL JOURNAL OF CARDIOLOGY, 179, 430-440. doi:10.1016/j.ijcard.2014.11.106

Carbone, S., Mauro, A. G., Mezzaroma, E., Kraskauskas, D., Marchetti, C., Buzzetti, R., . . . Toldo, S. (2015). A high-sugar and high-fat diet impairs cardiac systolic and diastolic function in mice. INTERNATIONAL JOURNAL OF CARDIOLOGY, 198, 66-69. doi:10.1016/j.ijcard.2015.06.136

Abbate, A., Morton, A. C., & Crossman, D. C. (2015). Anti-inflammatory therapies in myocardial infarction. LANCET, 385(9987), 2573-2574. doi:10.1016/S0140-6736(15)61153-9

Dixon, D. L., & Abbate, A. (2015). Potassium levels in acute myocardial infarction: definitely worth paying attention to. EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY, 1(4), 252-253. doi:10.1093/ehjcvp/pvv029

Binder, A., Ali, A., Chawla, R., Aziz, H. A., Abbate, A., & Jovin, I. S. (2015). Myocardial protection from ischemia-reperfusion injury post coronary revascularization. EXPERT REVIEW OF CARDIOVASCULAR THERAPY, 13(9), 1045-1057. doi:10.1586/14779072.2015.1070669

Al-Husseini, A., Wijesinghe, D. S., Farkas, L., Kraskauskas, D., Drake, J. I., Van Tassel, B., . . . Voelkel, N. F. (2015). Increased Eicosanoid Levels in the Sugen/Chronic Hypoxia Model of Severe Pulmonary Hypertension. PLOS ONE, 10(3). doi:10.1371/journal.pone.0120157

2014

Toldo, S., Mezzaroma, E., McGeough, M. D., Pena, C. A., Marchetti, C., Sonnino, C., . . . Abbate, A. (2015). Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart. CARDIOVASCULAR RESEARCH, 105(2), 203-212. doi:10.1093/cvr/cvu259

Toldo, S., Mezzaroma, E., Mauro, A. G., Salloum, F., Van Tassell, B. W., & Abbate, A. (2015). The Inflammasome in Myocardial Injury and Cardiac Remodeling. ANTIOXIDANTS & REDOX SIGNALING, 22(13), 1146-1161. doi:10.1089/ars.2014.5989

Li, S., Fossati, G., Marchetti, C., Modena, D., Pozzi, P., Reznikov, L. L., . . . Dinarello, C. A. (2015). Specific Inhibition of Histone Deacetylase 8 Reduces Gene Expression and Production of Proinflammatory Cytokines in Vitro and in Vivo. JOURNAL OF BIOLOGICAL CHEMISTRY, 290(4), 2368-2378. doi:10.1074/jbc.M114.618454

Toldo, S., Mezzaroma, E., Bressi, E., Marchetti, C., Carbone, S., Sonnino, C., . . . Abbate, A. (2014). Interleukin-1β Blockade Improves Left Ventricular Systolic/Diastolic Function and Restores Contractility Reserve in Severe Ischemic Cardiomyopathy in the Mouse. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 64(1), 1-6.

Marchetti, C., Chojnacki, J., Toldo, S., Mezzaroma, E., Tranchida, N., Rose, S. W., . . . Abbate, A. (2014). A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia-Reperfusion in the Mouse. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 63(4), 316-322. doi:10.1097/FJC.0000000000000053

Canada, J. M., Van Tassell, B. W., Christopher, S., Oddi, C., Abouzaki, N. A., Gambill, M. L., . . . Arena, R. (2014). Clinical predictors of response to anakinra in patients with heart failure. INTERNATIONAL JOURNAL OF CARDIOLOGY, 173(3), 537-539. doi:10.1016/j.ijcard.2014.03.023

Seropian, I. M., Toldo, S., Van Tassell, B. W., & Abbate, A. (2014). Anti-Inflammatory Strategies for Ventricular Remodeling Following ST-Segment Elevation Acute Myocardial Infarction. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 63(16), 1593-1603. doi:10.1016/j.jacc.2014.01.014

Falcao, R. A., Christopher, S., Oddi, C., Reznikov, L., Grizzard, J. D., Abouzaki, N. A., . . . Abbate, A. (2014). Interleukin-10 in patients with ST-segment elevation myocardial infarction. INTERNATIONAL JOURNAL OF CARDIOLOGY, 172(1), E6-E8. doi:10.1016/j.ijcard.2013.12.126

Toldo, S., Kannan, H., Bussani, R., Anzini, M., Sonnino, C., Sinagra, G., . . . Abbate, A. (2014). Formation of the inflammasome in acute myocarditis. INTERNATIONAL JOURNAL OF CARDIOLOGY, 171(3), E119-E121. doi:10.1016/j.ijcard.2013.12.137

D'Ascenzo, F., Cerratoa, E., Appleton, D., Moretti, C., Calcagno, A., Abouzaki, N., . . . Zoccai, G. B. (2014). Prognostic Indicators for Recurrent Thrombotic Events in HIV-infected Patients with Acute Coronary Syndromes: Use of Registry Data From 12 sites in Europe, South Africa and the United States. THROMBOSIS RESEARCH, 134(3), 558-564. doi:10.1016/j.thromres.2014.05.037

Biondi-Zoccai, G., Abbate, A., Landoni, G., Zangrillo, A., Vincent, J. L., D'Ascenzo, F., & Frati, G. (2014). An updated systematic review and meta-analysis on impedance threshold devices in patients undergoing cardiopulmonary resuscitation. HEART LUNG AND VESSELS, 6(2), 105-113.

Biondi-Zoccai, G., Peruzzi, M., Abbate, A., Gertz, Z. M., Benedetto, U., Tonelli, E., . . . Frati, G. (2014). Network meta-analysis on the comparative effectiveness and safety of transcatheter aortic valve implantation with CoreValve or Sapien devices versus surgical replacement. HEART LUNG AND VESSELS, 6(4), 232-243.

Peruzzi, M., De Luca, L., Thomsen, H. S., Romagnoli, E., D'Ascenzo, F., Mancone, M., . . . Biondi-Zoccai, G. (2014). A Network Meta-Analysis on Randomized Trials Focusing on the Preventive Effect of Statins on Contrast-Induced Nephropathy. BIOMED RESEARCH INTERNATIONAL, 2014. doi:10.1155/2014/213239

Biondi-Zoccai, G., Abbate, A., Peruzzi, M., & Frati, G. (2014). Observations, Trials, and Meta-Analyses: The Life Cycle of Evidence-Based Endovascular Therapy COMMENTARY. JOURNAL OF ENDOVASCULAR THERAPY, 21(5), 693-696. doi:10.1583/14-4713C.1

Cerrato, E., D'Ascenzo, F., Biondi-Zoccai, G. G., & Abbate, A. (2014). Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation: When Is "Enough" Enough?. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 64(1), 38-40.

Sonnino, C., Christopher, S., Oddi, C., Toldo, S., Falcao, R. A., Melchior, R. D., . . . Abbate, A. (2014). Leukocyte Activity in Patients with ST-Segment Elevation Acute Myocardial Infarction Treated with Anakinra. MOLECULAR MEDICINE, 20, 486-489. doi:10.2119/molmed.2014.00121

Toldo, S., Das, A., Mezzaroma, E., Chau, V. Q., Marchetti, C., Durrant, D., . . . Salloum, F. N. (2014). Induction of MicroRNA-21 With Exogenous Hydrogen Sulfide Attenuates Myocardial Ischemic and Inflammatory Injury in Mice. CIRCULATION-CARDIOVASCULAR GENETICS, 7(3), 311-320. doi:10.1161/CIRCGENETICS.113.000381

Van Tassell, B. W., Toldo, S., Mezzaroma, E., & Abbate, A. (2014). Response to Letter Regarding Article, "Targeting Interleukin-1 in Heart Disease". CIRCULATION, 130(7), E63. doi:10.1161/CIRCULATIONAHA.114.010274

Grinnan, D., Bogaard, H. -J., Grizzard, J., Van Tassell, B., Abbate, A., DeWilde, C., . . . Voelkel, N. F. (2014). Treatment of Group I Pulmonary Arterial Hypertension with Carvedilol Is Safe. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 189(12), 1562-1564. doi:10.1164/rccm.201311-2025LE

Abbate, A., Canada, J. M., Van Tassell, B. W., Wise, C. M., & Dinarello, C. A. (2014). Interleukin-1 blockade in rheumatoid arthritis and heart failure: A missed opportunity?. INTERNATIONAL JOURNAL OF CARDIOLOGY, 171(3), E125-E126. doi:10.1016/j.ijcard.2013.12.078

Toldo, S., Mezzaroma, E., O'Brien, L., Marchetti, C., Seropian, I. M., Voelkel, N. F., . . . Abbate, A. (2014). Interleukin-18 mediates interleukin-1-induced cardiac dysfunction. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 306(7), H1025-H1031. doi:10.1152/ajpheart.00795.2013

Van Tassell, B., Canada, J., Arena, R., & Abbate, A. (2014). Colchicine in Stable Chronic Heart Failure. JACC-HEART FAILURE, 2(5), 538. doi:10.1016/j.jchf.2014.04.009

O'Brien, L. C., Mezzaroma, E., Van Tassell, B. W., Marchetti, C., Carbone, S., Abbate, A., & Toldo, S. (2014). Interleukin-18 as a Therapeutic Target in Acute Myocardial Infarction and Heart Failure. MOLECULAR MEDICINE, 20, 221-229. doi:10.2119/molmed.2014.00034

Abbate, A. (2014). Ethical Challenges in Treating Friends and Family. NEW ENGLAND JOURNAL OF MEDICINE, 371(25), 2436-2437. doi:10.1056/NEJMc1412844

Marchetti, C., Toldo, S., Chojnacki, J., Mezzaroma, E., Federici, M., Voelkel, N. F., . . . Abbate, A. (2014). AN INHIBITOR OF THE NLRP3 INFLAMMASOME 16673-34-0 REDUCES INFARCT SIZE IN A MOUSE MODEL OF MYOCARDIAL ISCHEMIA REPERFUSION INJURY. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 63(12), A37. doi:10.1016/S0735-1097(14)60037-1

Bottinor, W., Turlington, J., Raza, S., Roberts, C. S., Malhotra, R., Jovin, I. S., & Abbate, A. (2014). Life-Saving Systemic Thrombolysis in a Patient with Massive Pulmonary Embolism and a Recent Hemorrhagic Cerebrovascular Accident. TEXAS HEART INSTITUTE JOURNAL, 41(2), 174-176. doi:10.14503/THIJ-12-3010

2013

Van Tassell, B. W., Arena, R., Biondi-Zoccai, G., Canada, J. M., Oddi, C., Abouzaki, N. A., . . . Abbate, A. (2014). Effects of Interleukin-1 Blockade With Anakinra on Aerobic Exercise Capacity in Patients With Heart Failure and Preserved Ejection Fraction (from the D-HART Pilot Study). AMERICAN JOURNAL OF CARDIOLOGY, 113(2), 321-327. doi:10.1016/j.amjcard.2013.08.047

Abbate, A., Van Tassel, B. W., Biondi-Zoccai, G., Kontos, M. C., Grizzard, J. D., Spillman, D. W., . . . Vetrovec, G. W. (2013). Effects of Interleukin-1 Blockade With Anakinra on Adverse Cardiac "Remodeling and Heart Failure After Acute Myocardial Infarction [from the Virginia Commonwealth. University-Anakinra Remodeling Trial (2) (VCU-ART2) Pilot Study]. AMERICAN JOURNAL OF CARDIOLOGY, 111(10), 1394-1400. doi:10.1016/j.amjcard.2013.01.287

Zoccai, G. B., Abbate, A., D'Ascenzo, F., Presutti, D., Peruzzi, M., Cavarretta, E., . . . Frati, G. (2013). Percutaneous coronary intervention in nonagenarians: pros and cons. JOURNAL OF GERIATRIC CARDIOLOGY, 10(1), 82-90. doi:10.3724/SP.J.1263.2012.11231

Biondi-Zoccai, G., Malavasi, V., D'Ascenzo, F., Abbate, A., Agostoni, P., Lotrionte, M., . . . Frati, G. (2013). Comparative effectiveness of novel oral anticoagulants for atrial fibrillation: evidence from pair-wise and warfarin-controlled network meta-analyses. HEART LUNG AND VESSELS, 5(1), 40-54.

Biondi-Zoccai, G., D'Ascenzo, F., Mancone, M., Romagnoli, E., Agostoni, P., Abbate, A., . . . Frati, G. (2013). Can we predict which patients with ST-elevation myocardial infarction benefit most from radial access? Evidence from frequentist and Bayesian meta-regressions of randomized trials. INTERNATIONAL JOURNAL OF CARDIOLOGY, 168(5), 4931-4934. doi:10.1016/j.ijcard.2013.07.087

D'Ascenzo, F., Cerrato, E., Moretti, C., Omede, P., Castagno, D., Gaita, F., . . . Biondi-Zoccai, G. (2013). Meta-analysis of coronary CT angiography in the emergency department: reply. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 14(6), 607-608. doi:10.1093/ehjci/jet028

Lotrionte, M., Biondi-Zoccai, G., Abbate, A., Lanzetta, G., D'Ascenzo, F., Malavasi, V., . . . Palazzoni, G. (2013). Review and Meta-Analysis of Incidence and Clinical Predictors of Anthracycline Cardiotoxicity. AMERICAN JOURNAL OF CARDIOLOGY, 112(12), 1980-1984. doi:10.1016/j.amjcard.2013.08.026

Chatterjee, S., Biondi-Zoccai, G., Abbate, A., D'Ascenzo, F., Castagno, D., Van Tassell, B., . . . Lichstein, E. (2013). Benefits of β blockers in patients with heart failure and reduced ejection fraction: network meta-analysis. BMJ-BRITISH MEDICAL JOURNAL, 346. doi:10.1136/bmj.f55

Abbate, A. (2013). The heart on fire: inflammasome and cardiomyopathy. EXPERIMENTAL PHYSIOLOGY, 98(2), 385. doi:10.1113/expphysiol.2012.069021

Lotrionte, M., Palazzoni, G., Abbate, A., De Marco, E., Mezzaroma, E., Di Persio, S., . . . Biondi-Zoccai, G. (2013). Cardiotoxicity of a non-pegylated liposomal doxorubicin-based regimen versus an epirubicin-based regimen for breast cancer: The LITE (Liposomal doxorubicin-Investigational chemotherapy-Tissue doppler imaging Evaluation) randomized pilot study. INTERNATIONAL JOURNAL OF CARDIOLOGY, 167(3), 1055-1057. doi:10.1016/j.ijcard.2012.10.079

Lotrionte, M., Cavarretta, E., Abbate, A., Mezzaroma, E., De Marco, E., Di Persio, S., . . . Palazzoni, G. (2013). Temporal Changes in Standard and Tissue Doppler Imaging Echocardiographic Parameters After Anthracycline Chemotherapy in Women With Breast Cancer. AMERICAN JOURNAL OF CARDIOLOGY, 112(7), 1005-1012. doi:10.1016/j.amjcard.2013.05.038

Seropian, I. M., Cerliani, J. P., Toldo, S., Van Tassell, B. W., Ilarregui, J. M., Gonzalez, G. E., . . . Rabinovich, G. A. (2013). Galectin-1 Controls Cardiac Inflammation and Ventricular Remodeling during Acute Myocardial Infarction. AMERICAN JOURNAL OF PATHOLOGY, 182(1), 29-40. doi:10.1016/j.ajpath.2012.09.022

Vecile, E., Dobrina, A., Salloum, F. N., Van Tassell, B. W., Falcione, A., Gustini, E., . . . Abbate, A. (2013). Intracellular Function of Interleukin-1 Receptor Antagonist in Ischemic Cardiomyocytes. PLOS ONE, 8(1). doi:10.1371/journal.pone.0053265

D'Ascenzo, F., Agostoni, P., Abbate, A., Castagno, D., Lipinski, M. J., Vetrovec, G. W., . . . Zoccai, G. B. (2013). Atherosclerotic coronary plaque regression and the risk of adverse cardiovascular events: A meta-regression of randomized clinical trials. ATHEROSCLEROSIS, 226(1), 178-185. doi:10.1016/j.atherosclerosis.2012.10.065

Al Husseini, A., Bagnato, G., Farkas, L., Gomez-Arroyo, J., Farkas, D., Mizuno, S., . . . Bogaard, H. J. (2013). Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats. EUROPEAN RESPIRATORY JOURNAL, 41(1), 104-114. doi:10.1183/09031936.00196511

Van Tassell, B. W., Seropian, I. M., Toldo, S., Mezzaroma, E., & Abbate, A. (2013). Interleukin-1β induces a reversible cardiomyopathy in the mouse. INFLAMMATION RESEARCH, 62(7), 637-640. doi:10.1007/s00011-013-0625-0

Voelkel, N. F., Gomez-Arroyo, J., Abbate, A., & Bogaard, H. J. (2013). Mechanisms of right heart failure-A work in progress and a plea for failure prevention. PULMONARY CIRCULATION, 3(1), 137-143. doi:10.4103/2045-8932.109957

Toldo, S., Goehe, R. W., Lotrionte, M., Mezzaroma, E., Sumner, E. T., Biondi-Zoccai, G. G. L., . . . Gewirtz, D. A. (2013). Comparative Cardiac Toxicity of Anthracyclines In Vitro and In Vivo in the Mouse. PLOS ONE, 8(3). doi:10.1371/journal.pone.0058421

Thanavaro, K. L., Shafi, S., Roberts, C., Cowley, M., Arrowood, J., Cassano, A., & Abbate, A. (2013). An unusual presentation of chest pain: Needle perforation of the right ventricle. HEART & LUNG, 42(3), 218-220. doi:10.1016/j.hrtlng.2013.02.002

Toldo, S., Mezzaroma, E., Van Tassell, B. W., Farkas, D., Marchetti, C., Voelkel, N. F., & Abbate, A. (2013). Interleukin-1 blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouse. EXPERIMENTAL PHYSIOLOGY, 98(3), 734-745. doi:10.1113/expphysiol.2012.069831

Van Tassell, B. W., Toldo, S., Mezzaroma, E., & Abbate, A. (2013). Targeting Interleukin-1 in Heart Disease. CIRCULATION, 128(17), 1910-1923. doi:10.1161/CIRCULATIONAHA.113.003199

Mezzaroma, E., Toldo, S., & Abbate, A. (2013). Role of NLRP3 (cryopyrin) in acute myocardial infarction. CARDIOVASCULAR RESEARCH, 99(1), 225-226. doi:10.1093/cvr/cvt123

Gomez-Arroyo, J., Mizuno, S., Szczepanek, K., Van Tassell, B., Natarajan, R., dos Remedios, C. G., . . . Voelkel, N. F. (2013). Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension. CIRCULATION-HEART FAILURE, 6(1), 136-+. doi:10.1161/CIRCHEARTFAILURE.111.966127

2012

Toldo, S., Breckenridge, D. G., Mezzaroma, E., Van Tassell, B. W., Shryock, J., Kannan, H., . . . Abbate, A. (2012). Inhibition of Apoptosis Signal-Regulating Kinase 1 Reduces Myocardial Ischemia-Reperfusion Injury in the Mouse. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 1(5). doi:10.1161/JAHA.112.002360

Abbate, A., Van Tassell, B. W., & Biondi-Zoccai, G. G. L. (2012). Blocking Interleukin-1 as a Novel Therapeutic Strategy for Secondary Prevention of Cardiovascular Events. BIODRUGS, 26(4), 217-233.

Biondi-Zoccai, G., Abbate, A., D'Ascenzo, F., Lotrionte, M., & Modena, M. G. (2012). Prasugrel During Primary Percutaneous Coronary Intervention: Evidence from Clinical Data. CURRENT VASCULAR PHARMACOLOGY, 10(4), 454-457. doi:10.2174/157016112800812782

Toldo, S., Schatz, A. M., Mezzaroma, E., Chawla, R., Stallard, T. W., Stallard, W. C., . . . Abbate, A. (2012). Recombinant Human Interleukin-1 Receptor Antagonist Provides Cardioprotection During Myocardial Ischemia Reperfusion in the Mouse. CARDIOVASCULAR DRUGS AND THERAPY, 26(3), 273-276. doi:10.1007/s10557-012-6389-x

Abbate, A., Hamza, M., Cassano, A. D., Melchior, R., Roberts, C., Grizzard, J., . . . Vetrovec, G. W. (2012). Sympathectomy as a treatment for refractory coronary artery spasm. INTERNATIONAL JOURNAL OF CARDIOLOGY, 161(1), E7-E9. doi:10.1016/j.ijcard.2012.03.006

Mezzaroma, E., Di, X., Graves, P., Toldo, S., Van Tassell, B. W., Kannan, H., . . . Abbate, A. (2012). A mouse model of radiation-induced cardiomyopathy. INTERNATIONAL JOURNAL OF CARDIOLOGY, 156(2), 231-233. doi:10.1016/j.ijcard.2012.01.038

Gomez-Arroyo, J., Saleem, S. J., Mizuno, S., Syed, A. A., Bogaard, H. J., Abbate, A., . . . Voelkel, N. F. (2012). A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 302(10), L977-L991. doi:10.1152/ajplung.00362.2011

Biondi-Zoccai, G., Agostoni, P., Abbate, A., D'Ascenzo, F., & Modena, M. G. (2012). Potential Pitfalls of Meta-Analyses of Observational Studies in Cardiovascular Research. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 59(3), 292-293. doi:10.1016/j.jacc.2011.09.053

Rocchiccioli, S., Andreassi, M. G., Cecchettini, A., Carpeggiani, C., Abbate, A. L., & Citti, L. (2012). Correlation between vitamin D binding protein expression and angiographic-proven coronary artery disease. CORONARY ARTERY DISEASE, 23(7), 426-431. doi:10.1097/MCA.0b013e328358781c

De-Giorgio, F., Grassi, V. M., Abbate, A., d'Aloja, E., & Arena, V. (2012). Causation or coincidence? A case of sudden death due to spontaneous coronary artery dissection in presence of myocardial bridging. INTERNATIONAL JOURNAL OF CARDIOLOGY, 159(2), E32-E34. doi:10.1016/j.ijcard.2011.11.056

Abbate, A., & Narula, J. (2012). Role of Apoptosis in Adverse Ventricular Remodeling. HEART FAILURE CLINICS, 8(1), 79-+. doi:10.1016/j.hfc.2011.08.010

Voelkel, N. F., Gomez-Arroyo, J., Abbate, A., Bogaard, H. J., & Nicolls, M. R. (2012). Pathobiology of pulmonary arterial hypertension and right ventricular failure. EUROPEAN RESPIRATORY JOURNAL, 40(6), 1555-1565. doi:10.1183/09031936.00046612

Gomez-Arroyo, J., Bogaard, H. J., Farkas, L., Abbate, A., & Voelkel, N. F. (2012). Pulmonary Hypertension and Right Ventricular Dysfunction in Chronic Lung Diseases: New Pathobiologic Concepts. CURRENT RESPIRATORY MEDICINE REVIEWS, 8(2), 116-122. doi:10.2174/157339812799859798

Toldo, S., Zhong, H., Mezzaroma, E., Van Tassell, B. W., Kannan, H., Zeng, D., . . . Abbate, A. (2012). GS-6201, a Selective Blocker of the A2B Adenosine Receptor, Attenuates Cardiac Remodeling after Acute Myocardial Infarction in the Mouse. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 343(3), 587-595. doi:10.1124/jpet.111.191288

Van Tassell, B. W., Bhardwaj, H. L., Grizzard, J. D., Kontos, M. C., Bogaard, H., Gomez-Arroyo, J., . . . Abbate, A. (2012). Right ventricular systolic dysfunction in patients with reperfused ST-segment elevation acute myocardial infarction. INTERNATIONAL JOURNAL OF CARDIOLOGY, 155(2), 314-316. doi:10.1016/j.ijcard.2011.12.004

Van Tassell, B. W., Arena, R. A., Toldo, S., Mezzaroma, E., Azam, T., Seropian, I. M., . . . Abbate, A. (2012). Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure. PLOS ONE, 7(3). doi:10.1371/journal.pone.0033438

2011

Mezzaroma, E., Toldo, S., Farkas, D., Seropian, I. M., Van Tassell, B. W., Salloum, F. N., . . . Abbate, A. (2011). The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(49), 19725-19730. doi:10.1073/pnas.1108586108

Stribling, W. K., Kontos, M. C., Abbate, A., Cooke, R., Vetrovec, G. W., Dai, D., . . . Lotun, K. (2011). Left Circumflex Occlusion in Acute Myocardial Infarction (from the National Cardiovascular Data Registry). AMERICAN JOURNAL OF CARDIOLOGY, 108(7), 959-963. doi:10.1016/j.amjcard.2011.05.027

Biondi-Zoccai, G., Lotrionte, M., Agostoni, P., Abbate, A., Romagnoli, E., Sangiorgi, G., . . . Sheiban, I. (2011). Adjusted indirect comparison meta-analysis of prasugrel versus ticagrelor for patients with acute coronary syndromes. INTERNATIONAL JOURNAL OF CARDIOLOGY, 150(3), 325-331. doi:10.1016/j.ijcard.2010.08.035

Van Tassell, B., Seropian, I., Toldo, S., Salloum, F., Smithson, L., Varma, A., . . . Abbate, A. (2011). Pharmocologic Inhibition of Myeloid Differentiation Factor 88 (MyD88) Prevents Left Ventricular Dilation and Hypertrophy After Experimental Acute Myocardial Infarction in the Mouse (vol 55, pg 385, 2010). JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 57(2), 272. doi:10.1097/FJC.0b013e31820a8de0

Biondi-Zoccai, G., D'Ascenzo, F., Abbate, A., Agostoni, P., & Modena, M. G. (2011). Agreement between adjusted indirect comparison and simplified network meta-analyses on prasugrel and ticagrelor (Reply to Passaro et al. - Int J Cardiol 2011). INTERNATIONAL JOURNAL OF CARDIOLOGY, 151(2), 228-229. doi:10.1016/j.ijcard.2011.06.036

Biondi-Zoccai, G., Abbate, A., & Sangiorgi, G. (2011). It's never too early! Evidence for rushing your acute coronary patients to the cath lab. EUROPEAN HEART JOURNAL, 32(1), 13-15. doi:10.1093/eurheartj/ehq346

Toldo, S., Boccellino, M., Rinaldi, B., Seropian, I. M., Mezzaroma, E., Severino, A., . . . Baldi, A. (2011). Altered Oxido-Reductive State in the Diabetic Heart: Loss of Cardioprotection due to Protein Disulfide Isomerase. MOLECULAR MEDICINE, 17(9-10), 1012-1021. doi:10.2119/molmed.2011.00100

Mazza, M., Romagnoli, E., Lotrionte, M., Abbate, A., Sheiban, I., & Biondi-Zoccai, G. (2011). A meta-analysis of selective serotonin reuptake inhibitors in acute coronary syndrome: cause for concern Reply. JOURNAL OF PSYCHOPHARMACOLOGY, 25(12), 1732-1733. doi:10.1177/0269881111413758

Marano, G., Traversi, G., Romagnoli, E., Catalano, V., Lotrionte, M., Abbate, A., . . . Mazza, M. (2011). Cardiologic side effects of psychotropic drugs. JOURNAL OF GERIATRIC CARDIOLOGY, 8(4), 243-253. doi:10.3724/SP.J.1263.2011.00243

Bogaard, H. J., Mizuno, S., Al Hussaini, A. A., Toldo, S., Abbate, A., Kraskauskas, D., . . . Voelkel, N. F. (2011). Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 183(10), 1402-1410. doi:10.1164/rccm.201007-1106OC

Shetty, R., Biondi-Zoccai, G. G. L., Abbate, A., Amin, M. S., & Jovin, I. S. (2011). Percutaneous renal artery intervention versus medical therapy in patients with renal artery stenosis: a meta-analysis. EUROINTERVENTION, 7(7), 844-851. doi:10.4244/EIJV7I7A132

Chau, V. Q., Salloum, F. N., Hoke, N. N., Abbate, A., & Kukreja, R. C. (2011). Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 300(6), H2272-H2279. doi:10.1152/ajpheart.00654.2010

Appleton, D., Abbate, A., & Biondi-Zoccai, G. (2011). Percutaneous Coronary Intervention for Persistent Occlusion of the Infarct-Related Artery: An Expanded View of the Evidence. ARCHIVES OF INTERNAL MEDICINE, 171(21), 1960-1961.

Toldo, S., Seropian, I. M., Mezzaroma, E., Van Tassell, B. W., Salloum, F. N., Lewis, E. C., . . . Abbate, A. (2011). Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 51(2), 244-251. doi:10.1016/j.yjmcc.2011.05.003

Abbate, A., Salloum, F. N., Van Tassell, B. W., Vecile, E., Toldo, S., Seropian, I., . . . Dobrina, A. (2011). Alterations in the Interleukin-1/Interleukin-1 Receptor Antagonist Balance Modulate Cardiac Remodeling following Myocardial Infarction in the Mouse. PLOS ONE, 6(11). doi:10.1371/journal.pone.0027923

Toldo, S., Bogaard, H. J., Van Tassell, B. W., Mezzaroma, E., Seropian, I. M., Robati, R., . . . Abbate, A. (2011). Right Ventricular Dysfunction following Acute Myocardial Infarction in the Absence of Pulmonary Hypertension in the Mouse. PLOS ONE, 6(3). doi:10.1371/journal.pone.0018102

Stribling, W. K., Kontos, M. C., Abbate, A., Cooke, R., Vetrovec, G. W., & Lotun, K. (2011). Clinical Outcomes in Patients with Acute Left Circumflex/Obtuse Marginal Occlusion Presenting with Myocardial Infarction. JOURNAL OF INTERVENTIONAL CARDIOLOGY, 24(1), 27-33. doi:10.1111/j.1540-8183.2010.00599.x

Zhu, Q., Wang, Z., Xia, M., Li, P. -L., Van Tassell, B. W., Abbate, A., . . . Li, N. (2011). Silencing of Hypoxia-Inducible Factor-1α Gene Attenuated Angiotensin II-Induced Renal Injury in Sprague-Dawley Rats. HYPERTENSION, 58(4), 657-664. doi:10.1161/HYPERTENSIONAHA.111.177626

Huizar, J. F., Kaszala, K., Potfay, J., Minisi, A. J., Lesnefsky, E. J., Abbate, A., . . . Wood, M. A. (2011). Left Ventricular Systolic Dysfunction Induced by Ventricular Ectopy A Novel Model for Premature Ventricular Contraction-Induced Cardiomyopathy. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 4(4), 543-U231. doi:10.1161/CIRCEP.111.962381

2010

Zardi, E. M., Abbate, A., Zardi, D. M., Dobrina, A., Margiotta, D., Van Tassel, B. W., . . . Sanyal, A. J. (2010). Cirrhotic Cardiomyopathy. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 56(7), 539-549. doi:10.1016/j.jacc.2009.12.075

Bogaard, H. J., Natarajan, R., Mizuno, S., Abbate, A., Chang, P. J., Chau, V. Q., . . . Voelkel, N. F. (2010). Adrenergic Receptor Blockade Reverses Right Heart Remodeling and Dysfunction in Pulmonary Hypertensive Rats. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 182(5), 652-660. doi:10.1164/rccm.201003-0335OC

Piro, M., Della Bona, R., Abbate, A., Biasucci, L. M., & Crea, F. (2010). Sex-Related Differences in Myocardial Remodeling. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 55(11), 1057-1065. doi:10.1016/j.jacc.2009.09.065

Varma, A., Appleton, D. L., Nusca, A., Lipinski, M. J., Goudreau, E., Cowley, M. J., . . . Abbate, A. (2010). Iron deficiency anemia and cardiac mortality in patients with left ventricular systolic dysfunction undergoing coronary stenting. MINERVA CARDIOANGIOLOGICA, 58(1), 1-10.

Patel, M. R., Peterson, E. D., Dai, D., Brennan, J. M., Redberg, R. F., Anderson, H. V., . . . Douglas, P. S. (2010). Low Diagnostic Yield of Elective Coronary Angiography. NEW ENGLAND JOURNAL OF MEDICINE, 362(10), 886-895. doi:10.1056/NEJMoa0907272

Lotrionte, M., Biondi-Zoccai, G., Imazio, M., Castagno, D., Moretti, C., Abbate, A., . . . Gaita, F. (2010). International collaborative systematic review of controlled clinical trials on pharmacologic treatments for acute pericarditis and its recurrences. AMERICAN HEART JOURNAL, 160(4), 662-670. doi:10.1016/j.ahj.2010.06.015

Zardi, E. M., Abbate, A., & Zardi, D. M. (2010). Cirrhotic Cardiomyopathy (vol 56, pg 539, 2010). JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 56(12), 1000. doi:10.1016/j.jacc.2010.08.003

Biondi-Zoccai, G., Moretti, C., Abbate, A., & Sheiban, I. (2010). Percutaneous coronary intervention for small vessel coronary artery disease. CARDIOVASCULAR REVASCULARIZATION MEDICINE, 11(3), 189-198. doi:10.1016/j.carrev.2009.04.007

Bollati, M., Tizzani, E., Moretti, C., Sciuto, F., Omede, P., Zoccai, G. B., . . . Sheiban, I. (2010). The future of new aortic valve replacement approaches. FUTURE CARDIOLOGY, 6(3), 351-360. doi:10.2217/FCA.10.14

Mazza, M., Lotrionte, M., Biondi-Zoccai, G., Abbate, A., Sheiban, I., & Romagnoli, E. (2010). Selective serotonin reuptake inhibitors provide significant lower re-hospitalization rates in patients recovering from acute coronary syndromes: evidence from a meta-analysis. JOURNAL OF PSYCHOPHARMACOLOGY, 24(12), 1785-1792. doi:10.1177/0269881109348176

Ghosh, S. S., Salloum, F. N., Abbate, A., Krieg, R., Sica, D. A., Gehr, T. W., & Kukreja, R. C. (2010). Curcumin prevents cardiac remodeling secondary to chronic renal failure through deactivation of hypertrophic signaling in rats. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 299(4), H975-H984. doi:10.1152/ajpheart.00154.2010

Binder, A., Seropian, I. M., Kontos, M. C., Van Tassell, B. W., Biondi-Zoccai, G. G. L., & Abbate, A. (2010). Limited value of brain natriuretic peptide as a prognostic marker in acute heart failure - A meta-analysis. INTERNATIONAL JOURNAL OF CARDIOLOGY, 145(3), 540-541. doi:10.1016/j.ijcard.2010.04.074

Abbate, A., Van Tassell, B. W., Seropian, I. M., Toldo, S., Robati, R., Varma, A., . . . Dinarello, C. A. (2010). Interleukin-1β modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse. EUROPEAN JOURNAL OF HEART FAILURE, 12(4), 319-322. doi:10.1093/eurjhf/hfq017

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