Research in Progress

Randall Schirra - Molecular Insights into Caveolae: Lessons from Structural Virology Skylar Loeb - A role for the lymphatic system in cardiometabolic heart failure Austin Hogwood - Interleukin-1 and Exercise Capacity in STEMI

Itaconate suppresses atherosclerosis by activating a Nrf2-dependent anti-inflammatory response in macrophages in mice. https://www.jci.org/articles/view/173034 Group 2 members:  Victoria MilosekKelsey WattsNareen Anwar

Trainees should prepare a 3-4 minute introduction about themselves and their project—no slides! Also, remember that the audience will be quiet diverse from 2nd year graduate students just getting into labs to faculty and also from very different areas. These … Read More

A trainee is randomly selected (by pulling a name from a jar) to give a 5-6 minute summary of their research project without slides indicating why their project is important, what has been done so far, what needs to be … Read More

Alex Clark - Systems analysis of gene regulatory networks driving cardiomyocyte identity Madeline Jackson - The role of Cx37 in lymphatic valve formation

Kelsey - Identification of sex dimorphisms in Endothelial-to-Mesenchymal Transition (endoMT) regulation in atherosclerotic disease Randall - Caveolin nanodiscs to investigate Cav-1 scaffolding Kaitlyn - Systems approaches identify drugs and genes regulating cardiomyocyte proliferation

Presenters - Katie Pavelec, Wyatt Schug, Maddie Jackson, and Skylar Loeb The paper is entitled: Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target https://www.sciencedirect.com/science/article/abs/pii/S0092867424010924?fr=RR-2&ref=pdf_download&rr=8d7d9c9dfbfbc97d

Gabrielle Largoza - Identifying Cellular Mechanisms of KRAS-driven bAVM Caitlin Pavelec - MYBPC3 W1082* Trucation Mutation Drives Hypertrophic Cardiomyopathy in a Murine Model Chase Binion - Characterization of Plaque-Targeted Peptide Amphiphile Nanoparticles in a Rodent Model of Atherosclerosis

Austin - The Brain-Heart Connection in Takotsubo Syndrome Abigayle - Microglia-Vasculature Association in Models of Immune Challenge

Wyatt - Basophil-Endothelium Interactions in Cardiometabolic Disease Rachel -Mechanosensitive Role of RBFOX2 in Alternative Splicing

Skylar Rodgers - Peptide Amphiphile Nanofibers as Targeted Therapy for Atherosclerosis  Skylar Loeb - Lymphatic regulation of cardiometabolic heart failure Sohel Shamsuzzaman - Role of Stem Cell Antigen-1 (Sca1) in Atherosclerosis Development and Late-Stage Pathogenesis