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Karen Reue, PhD
Hosted by: Mete Civelek, PhD
March 9, 2023 @ 11:00 am – 12:00 pm
Sex-biased genetic factors influence obesity, lipid absorption, and statin adverse effects
We are investigating sex differences in cardiometabolism to identify genetic factors that influence adiposity and lipid metabolism. We have identified histone demethylase enzymes that are encoded on the sex chromosomes as key determinants of sex-biased gene expression that contributes to white and brown adipose tissue function, postprandial lipid metabolism, and adverse responses to statin drugs.
Affiliation: Associate Director, UCLA/Caltech Medical Scientist (MD-PhD)Training Program, Professor and Vice Chair, Departments of Human Genetics and Medicine, UCLA, California