Stuart S. Berr

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Primary Appointment

Professor, Radiology- Radiology Research

Education

  • BA, Chemistry, Grinnell College, Grinnell, IA
  • PhD, Physical Chemistry, Wake Forest University, Winston-Salem, NC, Oak Ridge National Laboratory, Oak Ridge, TN
  • Postdoc, Chemistry, University of Virginia
  • Postdoc, Cardiology and Radiology, University of Virginia

Research Disciplines

Biochemistry, Cancer Biology, Cell and Developmental Biology, Metabolism, Molecular Pharmacology, Translational Science

Research Interests

Developing Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) techniques as a tool for basic biomedical research.

Research Description

My laboratory is involved with developing Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) techniques as a tool for basic biomedical research. I am currently developing, fabricating, and testing novel PET scanners that can be used inside high-field MRI scanners for simultaneous acquisition of PET and MRI data.

Personal Statement

My laboratory is involved with developing Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) techniques as a tool for basic biomedical research. I am currently developing, fabricating, and testing novel PET scanners that can be used inside high-field MRI scanners for simultaneous acquisition of PET and MRI data.

Selected Publications

Banizs AB, Huang T, Dryden K, Berr SS, Stone JR, Nakamoto RK, Shi W, He J, In vitro evaluation of endothelial exosomes as carriers for small interfering ribonucleic acid delivery., 2014; International journal of nanomedicine. 9() 4223-30. PMID: 25214786 | PMCID: PMC4159392

Zhang Y, Wang Y, Zuo Z, Wang Z, Roy J, Hou Q, Tong E, Hoffmann A, Sperberg E, Bredno J, Berr SS, Xie M, Lee K, Wintermark M, Effects of tissue plasminogen activator timing on blood-brain barrier permeability and hemorrhagic transformation in rats with transient ischemic stroke., 2014; Journal of the neurological sciences. 347(1) 148-54. PMID: 25292413

Locke LW, Mayo MW, Yoo AD, Williams MB, Berr SS, PET imaging of tumor associated macrophages using mannose coated 64Cu liposomes., 2012; Biomaterials. 33(31) 7785-93. PMID: 22840225

Xiao L, Zhang Y, Berr SS, Chordia MD, Pramoonjago P, Pu L, Pan D, A novel near-infrared fluorescence imaging probe for in vivo neutrophil tracking., 2012; Molecular imaging. 11(5) 372-82. PMID: 22954181

West AM, Anderson JD, Epstein FH, Meyer CH, Hagspiel KD, Berr SS, Harthun NL, Weltman AL, Annex BH, Kramer CM, Percutaneous intervention in peripheral artery disease improves calf muscle phosphocreatine recovery kinetics: a pilot study., 2012; Vascular medicine (London, England). 17(1) 3-9. PMID: 22363013 | PMCID: PMC3306608

Locke LW, Williams MB, Fairchild KD, Zhong M, Kundu BK, Berr SS, FDG-PET Quantification of Lung Inflammation with Image-Derived Blood Input Function in Mice., 2011; International journal of molecular imaging. 2011() 356730. PMID: 22187641 | PMCID: PMC3236466

Jehle AB, Xu Y, Dimaria JM, French BA, Epstein FH, Berr SS, Roy RJ, Kemp BA, Carey RM, Kramer CM, A nonpeptide angiotensin II type 2 receptor agonist does not attenuate postmyocardial infarction left ventricular remodeling in mice., 2011; Journal of cardiovascular pharmacology. 59(4) 363-8. PMID: 22157261 | PMCID: PMC3322306

West AM, Anderson JD, Epstein FH, Meyer CH, Wang H, Hagspiel KD, Berr SS, Harthun NL, Weltman AL, Dimaria JM, Hunter JR, Christopher JM, Kramer CM, Low-density lipoprotein lowering does not improve calf muscle perfusion, energetics, or exercise performance in peripheral arterial disease., 2011; Journal of the American College of Cardiology. 58(10) 1068-76. PMID: 21867844 | PMCID: PMC3182461

Beyers RJ, Smith RS, Xu Y, Piras BA, Salerno M, Berr SS, Meyer CH, Kramer CM, French BA, Epstein FH, Tâ -weighted MRI of post-infarct myocardial edema in mice., 2011; Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 67(1) 201-9. PMID: 21630350 | PMCID: PMC3188362

West AM, Anderson JD, Meyer CH, Epstein FH, Wang H, Hagspiel KD, Berr SS, Harthun NL, DiMaria JM, Hunter JR, Christopher JM, Chew JD, Winberry GB, Kramer CM, The effect of ezetimibe on peripheral arterial atherosclerosis depends upon statin use at baseline., 2011; Atherosclerosis. 218(1) 156-62. PMID: 21570685 | PMCID: PMC3157540

Zhang Y, Xiao L, Chordia MD, Locke LW, Williams MB, Berr SS, Pan D, Neutrophil targeting heterobivalent SPECT imaging probe: cFLFLF-PEG-TKPPR-99mTc., 2010; Bioconjugate chemistry. 21(10) 1788-93. PMID: 20843030

Locke LW, Chordia MD, Zhang Y, Kundu B, Kennedy D, Landseadel J, Xiao L, Fairchild KD, Berr SS, Linden J, Pan D, A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu., 2009; Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 50(5) 790-7. PMID: 19372473 | PMCID: PMC3004780

Zhang Y, Kundu B, Fairchild KD, Locke L, Berr SS, Linden J, Pan D, Synthesis of novel neutrophil-specific imaging agents for Positron Emission Tomography (PET) imaging., 2007; Bioorganic & medicinal chemistry letters. 17(24) 6876-8. PMID: 17959381 | PMCID: PMC2612577

Wu Y, McRoberts K, Berr SS, Frierson HF, Conaway M, Theodorescu D, Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia., 2006; Oncogene. 26(5) 765-73. PMID: 16878152