Services
What We Offer
We provide comprehensive support across diverse -omics platforms and analytical needs:
Genomics (Transcriptomics & Genetic Variation)
- Single-cell RNA-seq (scRNA-seq) – clustering, differential expression, cell-type annotation, trajectory inference / pseudotime
- Single-cell Multiome (RNA + ATAC) – joint transcriptome + chromatin profiles
- CITE-seq (RNA + surface protein)
- Spatial transcriptomics – 10x Visium, Slide-seq, GeoMx DSP
- Spatial proteomics – IMC, CODEX, MIBI, DSP platforms
- Bulk & long-read RNA-seq – Illumina, PacBio, Oxford Nanopore
- Whole-genome & exome sequencing (WGS/WES) – variant calling & annotation
- GWAS, eQTL/sQTL analysis – linking variants to expression and splicing traits
Epigenomics & Chromatin Profiling
- ATAC-seq – open-chromatin landscapes
- ChIP-seq / CUT&RUN / CUT&TAG – histone marks & TF binding
- DNA methylation – 850 K array, WGBS, RRBS
Microbiome Analysis
- 16S rRNA sequencing – taxonomic profiling, diversity metrics
- Shotgun metagenomics – functional annotation, resistome, virome, strain-level analysis
Metabolomics & Lipidomics
- Targeted and untargeted workflows – peak detection, normalization, pathway mapping
- Integration with transcriptomics & proteomics
Multi-Omics & Advanced Analytics
- Cross-dataset integration (e.g., transcriptome + proteome + methylome)
- Pathway & functional enrichment (GO, KEGG, Reactome, MSigDB, IPA)
- Gene-regulatory networks & cell-cell communication (CellPhoneDB, NicheNet)
- Custom visualizations – heatmaps, volcano plots, UMAPs, dot plots
Cancer Genomics & Clinical Correlation
- TCGA, GTEx, TARGET analyses
- Survival analysis and Cox regression with clinical metadata
- Biomarker discovery & validation
Structural Bioinformatics
- Protein-structure prediction (AlphaFold, RoseTTAFold)
- Protein–protein docking (ClusPro, HADDOCK, ZDOCK)
- Interface analysis, mutation modeling, dynamics
Statistical & Machine-Learning Analytics
- Classical statistics – linear/mixed-effects models, generalized linear models, survival & competing-risk analyses, power & sample-size calculations
- High-dimensional methods – DESeq2/edgeR for bulk data; MAST, limma-voom, and pseudobulk for single-cell
- Feature selection & predictive modeling – LASSO/elastic net, random forest, gradient-boosting, SVM
- Deep learning – autoencoders, CNN/RNN architectures for sequencing, imaging, and multimodal data (TensorFlow/PyTorch)
- Unsupervised learning – PCA, ICA, NMF, t-SNE, UMAP, graph-based clustering, topic modeling
- Explainability tools – SHAP, LIME, permutation importance
- Reproducible workflows – tidyverse/targets (R); scikit-learn/Scanpy (Python); Docker/Singularity
