Our mission is to understand the calcium signalling pathways that control the diameter of small blood vessels, with special focus on calcium entry channels in endothelial cells. We utilize high-speed imaging of localized calcium signals, patch clamp electrophysiology and functional studies coupled with transgenic mouse models. The ultimate goals are to understand how the networks of ion channels control local blood flow and vascular resistance and to use this information for unraveling pathological mechanisms and therapeutic approaches for vascular disorders.
For our most current list of publications, please click here.
Robert M. Berne Cardiovascular Research Center (aka CVRC)
Department of Molecular Physiology and Biological Physics
Cardiovascular Training Grant (CVTG and Facebook)