Publications

Selected Publications

  1. Khetarpal SA, Li H, Vitale T, Rhee J, Challa S, Castro C, Pabel S, Sun Y, Liu J, Bogoslavski D, Vargas-Castillo A, Smythers AL, Blackmore KA, Grauvogel L, Mittenbühler MJ, Khandekar MJ, Curtin C, Narvaez-Paliza JM, Wang C, Houstis NE, Sprenger H-G, Jurgens SJ, Biddinger KJ, Kuznetsov A, Freeman R, Ellinor PT, Nahrendorf M, Paulo JA, Gygi SP, Dumesic PA, Asnani A, Aragam KG, Puigserver P, Roh JD, Spiegelman BM*, Rosenzweig A*. Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α. Nature Cardiovascular Research. In press. *Denotes equal co-authorship. PMID: 40993371.
  2. Khetarpal SA, Li H, Lerchenmüller C, Rhee J, Rosenzweig A. Molecular Mediators of the Cardiac Benefits of Exercise. Circulation Research. 2025 Jul 7;137(2):163-183. Review. PMID: 40608861.
  3. Khetarpal, SA, Zeng X, Millar JS, Vitali C, Somasundara AV, Zanoni P, Landro JA, Barucci N, Zavadoski WJ, Sun Z, de Haard H, Toth IV, Peloso GM, Natarajan P, Cuchel M, Lund-Katz S, Phillips MC, Tall AR, Kathiresan S, DaSilva-Jardine P, Yates NA, Rader DJ. A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels. Nature Medicine. 2017, Sep; 23(9): 1086-1094. PMCID: 28825717.
  4. Khetarpal SA*, Schjoldager KT*, Christoffersen C, Raghavan A, Edmondson AC, Reutter HM, Ahmed B, Ouazzani R, Peloso GM, Vitali C, Zhao W, Somasundara AV, Millar JS, Park Y, Fernando G, Livanov V, Choi S, Noé E, Patel P, Ho SP; Myocardial Infarction Exome Sequencing Study, Kirchgessner TG, Wandall HH, Hansen L, Bennett EP, Vakhrushev SY, Saleheen D, Kathiresan S, Brown CD, Abou Jamra R, LeGuern E, Clausen H, Rader DJ. Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents. Cell Metabolism. 2016 Aug 9;24(2):234-45. * Denotes equal co-authorship. PMCID: 27508872.
  5. Zanoni P*, Khetarpal SA*, Larach DB*, Hancock-Cerutti WF, Millar JS, Cuchel M, DerOhannessian S, Kontush A, Surendran P, Saleheen D, Trompet S, Jukema JW, De Craen A, Deloukas P, Sattar N, Ford I, Packard C, Majumder Aa, Alam DS, Di Angelantonio E, Abecasis G, Chowdhury R, Erdmann J, Nordestgaard BG, Nielsen SF, Tybjærg-Hansen A, Schmidt RF, Kuulasmaa K, Liu DJ, Perola M, Blankenberg S, Salomaa V, Männistö S, Amouyel P, Arveiler D, Ferrieres J, Müller-Nurasyid M, Ferrario M, Kee F, Willer CJ, Samani N, Schunkert H, Butterworth AS, Howson JM, Peloso GM, Stitziel NO, Danesh J, Kathiresan S, Rader DJ; CHD Exome+ Consortium; CARDIoGRAM Exome Consortium; Global Lipids Genetics Consortium. Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease. Science. 2016 Mar 11;351(6278):1166-71. * Denotes equal co-authorship. 26965621.

For more of Dr. Sumeet Khetarpal's publications, please see:
Pubmed: https://pubmed.ncbi.nlm.nih.gov/?term=Khetarpal+SA%5Bauthor+name%5D&sort=pubdate
Google Scholar: https://scholar.google.com/citations?user=J5RasHoAAAAJ&hl=en