<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"
	xmlns:content="http://purl.org/rss/1.0/modules/content/"
	xmlns:wfw="http://wellformedweb.org/CommentAPI/"
	xmlns:dc="http://purl.org/dc/elements/1.1/"
	xmlns:atom="http://www.w3.org/2005/Atom"
	xmlns:sy="http://purl.org/rss/1.0/modules/syndication/"
	xmlns:slash="http://purl.org/rss/1.0/modules/slash/"
	>

<channel>
	<title>Isakson Lab &#8211; Robert M. Berne Cardiovascular Research Center</title>
	<atom:link href="https://www.cvrc.virginia.edu/tag/isakson-lab/feed/" rel="self" type="application/rss+xml" />
	<link>https://www.cvrc.virginia.edu</link>
	<description>World-Class Research</description>
	<lastBuildDate>Fri, 31 Jul 2026 19:50:20 +0000</lastBuildDate>
	<language>en-US</language>
	<sy:updatePeriod>
	hourly	</sy:updatePeriod>
	<sy:updateFrequency>
	1	</sy:updateFrequency>
	<generator>https://wordpress.org/?v=7.0.2</generator>

<image>
	<url>https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2022/09/cropped-cropped-bernecvrclogo.jpg?fit=32%2C32&#038;ssl=1</url>
	<title>Isakson Lab &#8211; Robert M. Berne Cardiovascular Research Center</title>
	<link>https://www.cvrc.virginia.edu</link>
	<width>32</width>
	<height>32</height>
</image> 
<site xmlns="com-wordpress:feed-additions:1">212955449</site>	<item>
		<title>Five SRIP Fellows Join the CVRC for Summer Research</title>
		<link>https://www.cvrc.virginia.edu/srip2026/</link>
		
		<dc:creator><![CDATA[Chris Baryiames]]></dc:creator>
		<pubDate>Tue, 14 Jul 2026 15:51:16 +0000</pubDate>
				<category><![CDATA[News]]></category>
		<category><![CDATA[Abbate Lab]]></category>
		<category><![CDATA[Isakson Lab]]></category>
		<category><![CDATA[Outreach]]></category>
		<category><![CDATA[SRIP]]></category>
		<guid isPermaLink="false">https://www.cvrc.virginia.edu/?p=6435</guid>

					<description><![CDATA[As part of this year&#8217;s Summer Research internship Program (SRIP), five undergraduate students have joined CVRC labs to build research skills and gain lab experience. Participants live at UVA for ten weeks, are partnered with a student mentor, and complete &#8230; <a class="kt-excerpt-readmore more-link" href="https://www.cvrc.virginia.edu/srip2026/">Read More</a>]]></description>
										<content:encoded><![CDATA[
<p class="wp-block-paragraph">As part of this year&#8217;s Summer Research internship Program (SRIP), five undergraduate students have joined CVRC labs to build research skills and gain lab experience. Participants live at UVA for ten weeks, are partnered with a student mentor, and complete an intensive professional development series throughout the program. The internship is capped by an internal conference where the students present their research. </p>



<div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained">
<div class="wp-block-media-text is-stacked-on-mobile" style="grid-template-columns:23% auto"><figure class="wp-block-media-text__media"><img data-recalc-dims="1" fetchpriority="high" decoding="async" width="576" height="1024" src="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1383.jpg?resize=576%2C1024&#038;ssl=1" alt="" class="wp-image-6436 size-full" srcset="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1383-scaled.jpg?resize=576%2C1024&amp;ssl=1 576w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1383-scaled.jpg?resize=169%2C300&amp;ssl=1 169w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1383-scaled.jpg?resize=768%2C1366&amp;ssl=1 768w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1383-scaled.jpg?resize=863%2C1536&amp;ssl=1 863w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1383-scaled.jpg?resize=1151%2C2048&amp;ssl=1 1151w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1383-scaled.jpg?w=1439&amp;ssl=1 1439w" sizes="(max-width: 576px) 100vw, 576px" /></figure><div class="wp-block-media-text__content">
<p class="wp-block-paragraph">Ruthvik Jeenigiri is working in the Abbate Lab to identify age-based differences in heart failure. “I’m South Asian, and South Asians are very disproportionately affected by heart conditions, so I’m excited to work in a cardiology lab,” Ruthvik explained. “I want to be a physician, so I’m enjoying working for a physician researcher. I’ve been able to shadow Dr. Abbate in the clinic and understand what his work is like.” Ruthvik will leave the SRIP program with more confidence in his research skills, ability to solve problems independently, and cardiovascular knowledge. “I’m learning things I wouldn’t be exposed to until medical school,” he said.</p>
</div></div>
</div></div>



<div class="wp-block-group"><div class="wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained">
<div class="wp-block-kadence-spacer aligncenter kt-block-spacer-6435_402de9-69"><div class="kt-block-spacer kt-block-spacer-halign-center"><hr class="kt-divider"/></div></div>
</div></div>



<div class="wp-block-media-text is-stacked-on-mobile" style="grid-template-columns:23% auto"><figure class="wp-block-media-text__media"><img data-recalc-dims="1" decoding="async" width="576" height="1024" src="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1190.jpg?resize=576%2C1024&#038;ssl=1" alt="" class="wp-image-6438 size-full" srcset="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1190-scaled.jpg?resize=576%2C1024&amp;ssl=1 576w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1190-scaled.jpg?resize=169%2C300&amp;ssl=1 169w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1190-scaled.jpg?resize=768%2C1366&amp;ssl=1 768w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1190-scaled.jpg?resize=863%2C1536&amp;ssl=1 863w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1190-scaled.jpg?resize=1151%2C2048&amp;ssl=1 1151w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1190-scaled.jpg?w=1439&amp;ssl=1 1439w" sizes="(max-width: 576px) 100vw, 576px" /></figure><div class="wp-block-media-text__content">
<p class="wp-block-paragraph">Gerardina Abbate, working under Antonio Abbate, MD, PhD, is searching for connections between the brain and heart in Takotsubo Syndrome. “Takotsubo Syndrome looks like a heart attack, but it isn’t,” she explained, “It’s triggered by an emotional or physical stressor, and we think the brain connection is overlooked. I’m interested in cardiology and neurology, so this project is a mix of both worlds that I like.” Gerardina hopes to become an expert who uses her specialist knowledge of this condition to raise awareness of it.</p>
</div></div>



<div class="wp-block-kadence-spacer aligncenter kt-block-spacer-6435_e9f784-a6"><div class="kt-block-spacer kt-block-spacer-halign-center"><hr class="kt-divider"/></div></div>



<div class="wp-block-media-text is-stacked-on-mobile" style="grid-template-columns:23% auto"><figure class="wp-block-media-text__media"><img data-recalc-dims="1" decoding="async" width="576" height="1024" src="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1174.jpg?resize=576%2C1024&#038;ssl=1" alt="" class="wp-image-6439 size-full" srcset="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1174-scaled.jpg?resize=576%2C1024&amp;ssl=1 576w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1174-scaled.jpg?resize=169%2C300&amp;ssl=1 169w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1174-scaled.jpg?resize=768%2C1366&amp;ssl=1 768w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1174-scaled.jpg?resize=863%2C1536&amp;ssl=1 863w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1174-scaled.jpg?resize=1151%2C2048&amp;ssl=1 1151w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1174-scaled.jpg?w=1439&amp;ssl=1 1439w" sizes="(max-width: 576px) 100vw, 576px" /></figure><div class="wp-block-media-text__content">
<p class="wp-block-paragraph">Dalma Kaszala is working in the Abbate Lab to understand the neurological underpinnings of Takotsubo Syndrome. The daughter of a cardiologist, Dalma’s interest in cardiology is grounded in understanding how the body’s different systems are networked. “Heart failure leads to the failure of so many other parts of the body—there’s a lot of variety in the cases and that’s really interesting,” she explained. SRIP provides opportunities to grow both as a researcher and communicator, especially important given her interest in clinical research.</p>
</div></div>



<div class="wp-block-kadence-spacer aligncenter kt-block-spacer-6435_140123-99"><div class="kt-block-spacer kt-block-spacer-halign-center"><hr class="kt-divider"/></div></div>



<div class="wp-block-media-text is-stacked-on-mobile" style="grid-template-columns:23% auto"><figure class="wp-block-media-text__media"><img data-recalc-dims="1" loading="lazy" decoding="async" width="576" height="1024" src="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1226.jpg?resize=576%2C1024&#038;ssl=1" alt="" class="wp-image-6440 size-full" srcset="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1226-scaled.jpg?resize=576%2C1024&amp;ssl=1 576w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1226-scaled.jpg?resize=169%2C300&amp;ssl=1 169w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1226-scaled.jpg?resize=768%2C1366&amp;ssl=1 768w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1226-scaled.jpg?resize=863%2C1536&amp;ssl=1 863w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1226-scaled.jpg?resize=1151%2C2048&amp;ssl=1 1151w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2026/07/DSCF1226-scaled.jpg?w=1439&amp;ssl=1 1439w" sizes="auto, (max-width: 576px) 100vw, 576px" /></figure><div class="wp-block-media-text__content">
<p class="wp-block-paragraph">Raegan Canada, mentored by Antonio Abbate, MD, PhD, is studying the brain structures in patients with Takotsubo Syndrome, a transient defect in the heart’s left ventricle, hoping to identify correlations that may explain the disease. “I am really interested in how the heart interacts with the rest of the body, and am very excited about Dr. Abbate&#8217;s work,” she said. Raegan’s work is exposing her to research’s “soft skills” – reading papers, assessing data, and presenting her findings.</p>
</div></div>



<p class="wp-block-paragraph"></p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">6435</post-id>	</item>
		<item>
		<title>Dr. Brant Isakson of the CVRC Awarded a $2.6 Million Grant to Study the Role of Renin in Hypertension</title>
		<link>https://www.cvrc.virginia.edu/dr-brant-isakson-of-the-cvrc-awarded-a-2-6-million-grant-to-study-the-role-of-renin-in-hypertension/</link>
		
		<dc:creator><![CDATA[sc3et]]></dc:creator>
		<pubDate>Tue, 18 Jun 2024 14:12:16 +0000</pubDate>
				<category><![CDATA[News]]></category>
		<category><![CDATA[Isakson]]></category>
		<category><![CDATA[Isakson Lab]]></category>
		<guid isPermaLink="false">https://www.cvrc.virginia.edu/?p=5225</guid>

					<description><![CDATA[Hypertension is the most common pathological indicator for cardiovascular diseases. The key biological system that regulates blood pressure is the renin-angiotensin-aldosterone system (RAAS); its dysregulation at almost any level can precipitate hypertension. For this reason, pathways in the RAAS can &#8230; <a class="kt-excerpt-readmore more-link" href="https://www.cvrc.virginia.edu/dr-brant-isakson-of-the-cvrc-awarded-a-2-6-million-grant-to-study-the-role-of-renin-in-hypertension/">Read More</a>]]></description>
										<content:encoded><![CDATA[<div class="wp-block-image">
<figure class="alignright size-full is-resized"><img data-recalc-dims="1" loading="lazy" decoding="async" width="642" height="800" src="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2023/03/brant.jpg?resize=642%2C800&#038;ssl=1" alt="" class="wp-image-4518" style="width:250px" srcset="https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2023/03/brant.jpg?w=642&amp;ssl=1 642w, https://i0.wp.com/www.cvrc.virginia.edu/wp-content/uploads/2023/03/brant.jpg?resize=241%2C300&amp;ssl=1 241w" sizes="auto, (max-width: 642px) 100vw, 642px" /><figcaption class="wp-element-caption">Brant Isakson, PhD</figcaption></figure>
</div>


<p class="wp-block-paragraph">Hypertension is the most common pathological indicator for cardiovascular diseases. The key biological system that regulates blood pressure is the renin-angiotensin-aldosterone system (RAAS); its dysregulation at almost any level can precipitate hypertension. For this reason, pathways in the RAAS can be manipulated for pharmacological interventions (e.g., ACE inhibitors).</p>



<p class="wp-block-paragraph">New research by Brant Isakson, PhD, a professor in the Department of Molecular Physiology and Biological Physics, will interrogate the release of renin, the rate limiting step of activation of the RAAS, from juxtaglomerular (JG) cells in the afferent arterioles. Specifically, the application is focused on his recent work involving Pannexin1 channels in JG cells, as well as how Pannexin1 channels may be coupled to PIEZO1 channels.</p>



<p class="wp-block-paragraph">Dr. Isakson’s research will be supported by a $2.6 million grant from the National Heart, Lung, and Blood Institute. The long-term outcome from the studies may be a novel pharmacological target for treatment of hypertension.</p>



<p class="wp-block-paragraph">As an emerging leader in cardiovascular research, he was awarded the <a href="https://news.med.virginia.edu/honors-awards/brant-isakson-phd-receives-prestigious-2024-robert-m-berne-distinguished-lectureship-of-the-american-physiological-society/" target="_blank" rel="noreferrer noopener">2024 Robert M. Berne Distinguished Lectureship</a> last year.</p>



<p class="wp-block-paragraph"><a href="https://news.med.virginia.edu/research/brant-isakson-phd-awarded-2-6-million-to-study-the-role-of-renin-in-hypertension/" target="_blank" rel="noreferrer noopener">View the article at the SOM website</a></p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">5225</post-id>	</item>
	</channel>
</rss>
