Robert M. Strieter
- Email: rms4w@virginia.edu
- Phone: 982-6999
Primary Appointment
Professor, Medicine
Research Interests
Cytokine and Chemokine Biology As Related to Human Diseases
Research Description
Personal Statement
Selected Publications
Hou Y, Wu Y, Farooq SM, Guan X, Wang S, Liu Y, Oblak JJ, Holcomb J, Jiang Y, Strieter RM, Lasley RD, Arbab AS, Sun F, Li C, Yang Z, A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis., 2015; Stem cell research. 14(2) 133-43. PMID: 25622052
Choi YH, Burdick MD, Strieter BA, Mehrad B, Strieter RM, CXCR4, but not CXCR7, discriminates metastatic behavior in non-small cell lung cancer cells., 2013; Molecular cancer research : MCR. 12(1) 38-47. PMID: 24025971 | PMCID: PMC4262747
Mehrad B, Strieter RM, Fibrocytes and the pathogenesis of diffuse parenchymal lung disease., 2012; Fibrogenesis & tissue repair. 5() S22. PMID: 23259468 | PMCID: PMC3368792
Keeley EC, Mehrad B, Strieter RM, The role of fibrocytes in fibrotic diseases of the lungs and heart., 2011; Fibrogenesis Tissue Repair. 4(0) 2.0. PMID: | PMCID: PMC3027110
Dengel LT, Norrod AG, Gregory BL, Clancy-Thompson E, Burdick MD, Strieter RM, Slingluff Jr, Mullins DW, Interferons induce CXCR3-cognate chemokine production by human metastatic melanoma., 2010; J Immunother. 33(9) 965-74. PMID: | PMCID: NIHMS253549
Crawford MA, Burdick MD, Glomski IJ, Boyer AE, Barr JR, Mehrad B, Strieter RM, Hughes MA, Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection., 2010; PLoS Pathog. 6(11) e1001199. PMID: | PMCID: PMC2987825
Keeley EC, Mehrad B, Strieter RM, Chemokines as mediators of tumor angiogenesis and neovascularization., 2010; Exp Cell Res. 0(0) null. PMID:
Choi YH, Burdick MD, Strieter RM, Human circulating fibrocytes have the capacity to differentiate osteoblasts and chondrocytes., 2010; Int J Biochem Cell Biol. 42(5) 662-71. PMID: | PMCID: PMC2835809
Keeley EC, Mehrad B, Strieter RM, Fibrocytes: bringing new insights into mechanisms of inflammation and fibrosis., 2010; Int J Biochem Cell Biol. 42(4) 535-42. PMID: | PMCID: PMC2835833
Li L, Huang L, Vergis AL, Ye H, Bajwa A, Narayan V, Strieter RM, Rosin DL, Okusa MD, IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury., 2010; J Clin Invest. 120(1) 331-42. PMID: | PMCID: PMC2798679
Keeley EC, Mehrad B, Strieter RM, The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of fibrotic disorders., 2009; Thromb Haemost. 101(4) 613-8. PMID:
Mehrad B, Burdick MD, Strieter RM, Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis., 2009; Int J Biochem Cell Biol. 41(8) 1708-18. PMID: | PMCID: PMC2681415
Wallace KL, Marshall MA, Ramos SI, Lannigan JA, Field JJ, Strieter RM, Linden J, NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines., 2009; Blood. 114(3) 667-76. PMID: | PMCID: PMC2713467
Park SJ, Hughes MA, Burdick M, Strieter RM, Mehrad B, Early NK cell-derived IFN-{gamma} is essential to host defense in neutropenic invasive aspergillosis., 2009; J Immunol. 182(7) 4306-12. PMID:
Crawford MA, Zhu Y, Green CS, Burdick MD, Sanz P, Alem F, O'Brien AD, Mehrad B, Strieter RM, Hughes MA, Antimicrobial effects of interferon-inducible CXC chemokines against Bacillus anthracis spores and bacilli., 2009; Infect Immun. 77(4) 1664-78. PMID: | PMCID: PMC2663164
Keeley EC, Mehrad B, Strieter RM, Chemokines as mediators of neovascularization., 2008; Arterioscler Thromb Vasc Biol. 28(11) 1928-36. PMID: | PMCID: PMC2735456
Strieter RM, Out of the shadows: CXC chemokines in promoting aberrant lung cancer angiogenesis., 2008; Cancer Prev Res (Phila). 1(5) 305-7. PMID: | PMCID: PMC2614299
Strieter RM, What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis., 2008; Proc Am Thorac Soc. 5(3) 305-10. PMID: | PMCID: PMC2645241
Mehrad B, Keane MP, Gomperts BN, Strieter RM, Circulating progenitor cells in chronic lung disease., 2007; Expert Rev Respir Med. 1(1) 157-65. PMID:
Mehrad B, Keane MP, Strieter RM, Chemokines as mediators of angiogenesis., 2007; Thromb Haemost. 97(5) 755-62. PMID:
Strieter RM, Gomperts BN, Keane MP, The role of CXC chemokines in pulmonary fibrosis., 2007; J Clin Invest. 117(3) 549-56. PMID: | PMCID: PMC1804376
Mehrad B, Burdick MD, Zisman DA, Keane MP, Belperio JA, Strieter RM, Circulating peripheral blood fibrocytes in human fibrotic interstitial lung disease., 2007; Biochem Biophys Res Commun. 353(1) 104-8. PMID:
Strieter RM, Keeley EC, Burdick MD, Mehrad B, The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting pulmonary fibrosis., ; Trans Am Clin Climatol Assoc. 120(0) 49-59. PMID: | PMCID: PMC2744511
Lapar DJ, Burdick MD, Emaminia A, Harris DA, Strieter BA, Liu L, Robbins M, Kron IL, Strieter RM, Lau CL, Circulating fibrocytes correlate with bronchiolitis obliterans syndrome development after lung transplantation: a novel clinical biomarker., ; Ann Thorac Surg. 92(2) 470-7. PMID:
Keeley EC, Moorman JR, Liu L, Gimple LW, Lipson LC, Ragosta M, Taylor AM, Lake DE, Burdick MD, Mehrad B, Strieter RM, Plasma chemokine levels are associated with the presence and extent of angiographic coronary collaterals in chronic ischemic heart disease., ; PLoS One. 6(6) e21174. PMID: | PMCID: PMC3120847
Lapar DJ, Burdick MD, Emaminia A, Harris DA, Strieter BA, Liu L, Robbins M, Kron IL, Strieter RM, Lau CL, Circulating fibrocytes correlate with bronchiolitis obliterans syndrome development after lung transplantation: a novel clinical biomarker., ; Ann Thorac Surg. 92(2) 470-7. PMID:
Keeley EC, Mehrad B, Strieter RM, CXC chemokines in cancer angiogenesis and metastases., ; Adv Cancer Res. 106(0) 91-111. PMID: