| Position: Professor
Office Phone: 434-924-9974
Office Address: Jordan 5240
Messenger Mail: PO Box 800735
PubMed listings for Patrice Guyenet
My research is a branch of Integrative Neuroscience, a discipline that seeks to understand how the brain processes specific types of information. The laboratory studies how the mammalian brain regulates respiration and blood pressure, two physiological processes that are dysfunctional in very common diseases (hypertension, obesity, apneic syndromes, heart failure, etc.). The work consists of identifying relevant neuronal networks in rodents using electrophysiologic and neuroanatomic methods. The main focus is on a region of the brainstem that provides the chemical drive to breathe and contains the neurons that maintain blood pressure.
PG Guyenet, DK Mulkey, RL Stornetta, DA. Bayliss (2005) Regulation of ventral surface chemoreceptors by the central respiratory pattern generator. J Neurosci 25: 8938-8947.
Guyenet, PG (2006) The sympathetic control of blood pressure. Nat Rev Neurosci 7: 335-346.
Takakura AC, Moreira TS, Colombari E, West GH, Stornetta RL, & Guyenet, PG (2006) Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in rats. J Physiol (London) 572: 503-523.
DK Mulkey, RL Stornetta, MC Weston, JR Simmons, A Parker, DA. Bayliss and PG Guyenet. (2004) Respiratory control by ventral surface chemoreceptors. Nature Neuroscience 7: 1360-1369.